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Items: 1 to 20 of 105

1.
2.

The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation.

Dembitz V, Lalic H, Ostojic A, Vrhovac R, Banfic H, Visnjic D.

Int J Hematol. 2015 Jul;102(1):12-24. doi: 10.1007/s12185-015-1776-2.

PMID:
25758096
3.
4.

5-Aminoimidazole-4-carboxamide ribonucleoside induces differentiation of acute myeloid leukemia cells.

Lalic H, Dembitz V, Lukinovic-Skudar V, Banfic H, Visnjic D.

Leuk Lymphoma. 2014 Oct;55(10):2375-83. doi: 10.3109/10428194.2013.876633.

PMID:
24359245
5.

Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase.

Al-Moujahed A, Nicolaou F, Brodowska K, Papakostas TD, Marmalidou A, Ksander BR, Miller JW, Gragoudas E, Vavvas DG.

Invest Ophthalmol Vis Sci. 2014 Apr 29;55(7):4175-85. doi: 10.1167/iovs.13-12856.

6.

Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells.

Wang R, Xia L, Gabrilove J, Waxman S, Jing Y.

Leukemia. 2013 Feb;27(2):315-24. doi: 10.1038/leu.2012.180.

7.

Apoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic trioxide and glycolytic inhibitors, and regulation by oxidative stress and protein kinase activities.

Estañ MC, Calviño E, Calvo S, Guillén-Guío B, Boyano-Adánez Mdel C, de Blas E, Rial E, Aller P.

PLoS One. 2014 Dec 15;9(12):e115250. doi: 10.1371/journal.pone.0115250.

8.
9.

The influence of the BRAF V600E mutation in thyroid cancer cell lines on the anticancer effects of 5-aminoimidazole-4-carboxamide-ribonucleoside.

Choi HJ, Kim TY, Chung N, Yim JH, Kim WG, Kim JA, Kim WB, Shong YK.

J Endocrinol. 2011 Oct;211(1):79-85. doi: 10.1530/JOE-11-0260.

10.

2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.

Estañ MC, Calviño E, de Blas E, Boyano-Adánez Mdel C, Mena ML, Gómez-Gómez M, Rial E, Aller P.

Biochem Pharmacol. 2012 Dec 15;84(12):1604-16. doi: 10.1016/j.bcp.2012.09.022.

PMID:
23041229
11.
13.

AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells.

Agarwal S, Bell CM, Rothbart SB, Moran RG.

J Biol Chem. 2015 Nov 13;290(46):27473-86. doi: 10.1074/jbc.M115.665133.

14.

Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.

Ozpolat B, Akar U, Zorrilla-Calancha I, Vivas-Mejia P, Acevedo-Alvarez M, Lopez-Berestein G.

Apoptosis. 2008 Jul;13(7):915-28. doi: 10.1007/s10495-008-0222-9.

PMID:
18491231
15.

Synergistic antiproliferative effect of arsenic trioxide combined with bortezomib in HL60 cell line and primary blasts from patients affected by myeloproliferative disorders.

Canestraro M, Galimberti S, Savli H, Palumbo GA, Tibullo D, Nagy B, Guerrini F, Piaggi S, Cine N, Metelli MR, Petrini M.

Cancer Genet Cytogenet. 2010 Jun;199(2):110-20. doi: 10.1016/j.cancergencyto.2010.02.010.

PMID:
20471514
16.

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.

Guo D, Hildebrandt IJ, Prins RM, Soto H, Mazzotta MM, Dang J, Czernin J, Shyy JY, Watson AD, Phelps M, Radu CG, Cloughesy TF, Mischel PS.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12932-7. doi: 10.1073/pnas.0906606106.

17.

AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia.

Kuznetsov JN, Leclerc GJ, Leclerc GM, Barredo JC.

Mol Cancer Ther. 2011 Mar;10(3):437-47. doi: 10.1158/1535-7163.MCT-10-0777.

19.

Src family kinase inhibitor PP2 enhances differentiation of acute promyelocytic leukemia cell line induced by combination of all-trans-retinoic acid and arsenic trioxide.

Jung YS, Cheong HJ, Kim SJ, Kim KH, Lee N, Park HS, Won JH.

Leuk Res. 2014 Aug;38(8):977-82. doi: 10.1016/j.leukres.2014.05.019.

PMID:
24953245
20.

Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.

Beauchamp EM, Kosciuczuk EM, Serrano R, Nanavati D, Swindell EP, Viollet B, O'Halloran TV, Altman JK, Platanias LC.

Mol Cancer Ther. 2015 Jan;14(1):202-12. doi: 10.1158/1535-7163.MCT-14-0665-T.

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