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Kinetics of IL-23 and IL-12 secretion in response to Toxoplasma gondii antigens from THP-1 monocytic cells.

Quan JH, Zhou W, Cha GH, Choi IW, Shin DW, Lee YH.

Korean J Parasitol. 2013 Feb;51(1):85-92. doi: 10.3347/kjp.2013.51.1.85. Epub 2013 Feb 18.


Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15.

Gov L, Karimzadeh A, Ueno N, Lodoen MB.

MBio. 2013 Jul 9;4(4). pii: e00255-13. doi: 10.1128/mBio.00255-13.


Toxoplasma gondii triggers secretion of interleukin-12 but low level of interleukin-10 from the THP-1 human monocytic cell line.

Aldebert D, Durand F, Mercier C, Brenier-Pinchart MP, Cesbron-Delauw MF, Pelloux H.

Cytokine. 2007 Mar;37(3):206-11. Epub 2007 May 23.


HIV infection suppresses type 1 lymphokine and IL-12 responses to Toxoplasma gondii but fails to inhibit the synthesis of other parasite-induced monokines.

Gazzinelli RT, Bala S, Stevens R, Baseler M, Wahl L, Kovacs J, Sher A.

J Immunol. 1995 Aug 1;155(3):1565-74.


Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells.

Quan JH, Chu JQ, Kwon J, Choi IW, Ismail HA, Zhou W, Cha GH, Zhou Y, Yuk JM, Jo EK, Lee YH.

PLoS One. 2015 Nov 3;10(11):e0141550. doi: 10.1371/journal.pone.0141550. eCollection 2015.


Trophoblast cells are able to regulate monocyte activity to control Toxoplasma gondii infection.

Castro AS, Alves CM, Angeloni MB, Gomes AO, Barbosa BF, Franco PS, Silva DA, Martins-Filho OA, Mineo JR, Mineo TW, Ferro EA.

Placenta. 2013 Mar;34(3):240-7. doi: 10.1016/j.placenta.2012.12.006. Epub 2013 Jan 5.


The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion.

Tosh KW, Mittereder L, Bonne-Annee S, Hieny S, Nutman TB, Singer SM, Sher A, Jankovic D.

J Immunol. 2016 Jan 1;196(1):345-56. doi: 10.4049/jimmunol.1501558. Epub 2015 Nov 23.


Role of CD80 (B7.1) and CD86 (B7.2) in the immune response to an intracellular pathogen.

Subauste CS, de Waal Malefyt R, Fuh F.

J Immunol. 1998 Feb 15;160(4):1831-40.


Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A.

J Immunol. 2002 Jun 15;168(12):5997-6001.


Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses.

Morgado P, Sudarshana DM, Gov L, Harker KS, Lam T, Casali P, Boyle JP, Lodoen MB.

Infect Immun. 2014 Oct;82(10):4047-55. doi: 10.1128/IAI.01615-14. Epub 2014 Jul 14.


Toxoplasma gondii: proteomic analysis of antigenicity of soluble tachyzoite antigen.

Ma GY, Zhang JZ, Yin GR, Zhang JH, Meng XL, Zhao F.

Exp Parasitol. 2009 May;122(1):41-6. doi: 10.1016/j.exppara.2009.01.011. Epub 2009 Jan 30.


Immunization with excreted/secreted proteins in AS/n mice activating cellular and humoral response against Toxoplasma gondii infection.

Costa-Silva TA, Borges MM, Galhardo CS, Pereira-Chioccola VL.

Acta Trop. 2012 Dec;124(3):203-9. doi: 10.1016/j.actatropica.2012.08.013. Epub 2012 Aug 23.


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