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Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins down regulate both DC-SIGN and DC-SIGNR.

Lang SM, Bynoe MO, Karki R, Tartell MA, Means RE.

PLoS One. 2013;8(2):e58056. doi: 10.1371/journal.pone.0058056. Epub 2013 Feb 27.


Molecular mechanism of BST2/tetherin downregulation by K5/MIR2 of Kaposi's sarcoma-associated herpesvirus.

Mansouri M, Viswanathan K, Douglas JL, Hines J, Gustin J, Moses AV, Früh K.

J Virol. 2009 Oct;83(19):9672-81. doi: 10.1128/JVI.00597-09. Epub 2009 Jul 15.


[The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway].

Bénichou S, Benmerah A.

Med Sci (Paris). 2003 Jan;19(1):100-6. Review. French.


Downregulation of gamma interferon receptor 1 by Kaposi's sarcoma-associated herpesvirus K3 and K5.

Li Q, Means R, Lang S, Jung JU.

J Virol. 2007 Mar;81(5):2117-27. Epub 2006 Dec 13.


Human herpesvirus 8 infects and replicates in primary cultures of activated B lymphocytes through DC-SIGN.

Rappocciolo G, Hensler HR, Jais M, Reinhart TA, Pegu A, Jenkins FJ, Rinaldo CR.

J Virol. 2008 May;82(10):4793-806. doi: 10.1128/JVI.01587-07. Epub 2008 Mar 12.


Kaposi's sarcoma-associated herpesvirus K3 and K5 ubiquitin E3 ligases have stage-specific immune evasion roles during lytic replication.

Brulois K, Toth Z, Wong LY, Feng P, Gao SJ, Ensser A, Jung JU.

J Virol. 2014 Aug;88(16):9335-49. doi: 10.1128/JVI.00873-14. Epub 2014 Jun 4.


The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the Toll-like receptor-induced proinflammatory cytokine response.

Bussey KA, Reimer E, Todt H, Denker B, Gallo A, Konrad A, Ottinger M, Adler H, Stürzl M, Brune W, Brinkmann MM.

J Virol. 2014 Aug;88(16):9245-59. doi: 10.1128/JVI.00841-14. Epub 2014 Jun 4.


Immune evasion by a novel family of viral PHD/LAP-finger proteins of gamma-2 herpesviruses and poxviruses.

Früh K, Bartee E, Gouveia K, Mansouri M.

Virus Res. 2002 Sep;88(1-2):55-69. Review.


DC-SIGN is a receptor for human herpesvirus 8 on dendritic cells and macrophages.

Rappocciolo G, Jenkins FJ, Hensler HR, Piazza P, Jais M, Borowski L, Watkins SC, Rinaldo CR Jr.

J Immunol. 2006 Feb 1;176(3):1741-9.


A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I.

Parkinson MD, Piper SC, Bright NA, Evans JL, Boname JM, Bowers K, Lehner PJ, Luzio JP.

Biochem J. 2015 Oct 1;471(1):79-88. doi: 10.1042/BJ20150336. Epub 2015 Jul 28.


The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells.

Greene W, Zhang W, He M, Witt C, Ye F, Gao SJ.

PLoS Pathog. 2012;8(5):e1002703. doi: 10.1371/journal.ppat.1002703. Epub 2012 May 17.


Major histocompatibility complex class I molecules are down-regulated at the cell surface by the K5 protein encoded by Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8.

Haque M, Ueda K, Nakano K, Hirata Y, Parravicini C, Corbellino M, Yamanishi K.

J Gen Virol. 2001 May;82(Pt 5):1175-80.


Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR.

Pöhlmann S, Zhang J, Baribaud F, Chen Z, Leslie GJ, Lin G, Granelli-Piperno A, Doms RW, Rice CM, McKeating JA.

J Virol. 2003 Apr;77(7):4070-80.


The Kaposi's sarcoma-associated herpesvirus ORF34 protein binds to HIF-1α and causes its degradation via the proteasome pathway.

Haque M, Kousoulas KG.

J Virol. 2013 Feb;87(4):2164-73. doi: 10.1128/JVI.02460-12. Epub 2012 Dec 5.


Characterization of entry and infection of monocytic THP-1 cells by Kaposi's sarcoma associated herpesvirus (KSHV): role of heparan sulfate, DC-SIGN, integrins and signaling.

Kerur N, Veettil MV, Sharma-Walia N, Sadagopan S, Bottero V, Paul AG, Chandran B.

Virology. 2010 Oct 10;406(1):103-16. doi: 10.1016/j.virol.2010.07.012. Epub 2010 Aug 1.


Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function.

Rappocciolo G, Jais M, Piazza PA, DeLucia DC, Jenkins FJ, Rinaldo CR.

J Virol. 2017 Sep 27;91(20). pii: e00909-17. doi: 10.1128/JVI.00909-17. Print 2017 Oct 15.


Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation.

Rhodes DA, Boyle LH, Boname JM, Lehner PJ, Trowsdale J.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16240-5. doi: 10.1073/pnas.1003421107. Epub 2010 Aug 30.


Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone.

Brulois KF, Chang H, Lee AS, Ensser A, Wong LY, Toth Z, Lee SH, Lee HR, Myoung J, Ganem D, Oh TK, Kim JF, Gao SJ, Jung JU.

J Virol. 2012 Sep;86(18):9708-20. doi: 10.1128/JVI.01019-12. Epub 2012 Jun 27.

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