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Items: 1 to 20 of 105


Establishment of a cell-type-specific genetic network by the mediator complex component Med1.

Pope NJ, Bresnick EH.

Mol Cell Biol. 2013 May;33(10):1938-55. doi: 10.1128/MCB.00141-13. Epub 2013 Mar 4.


Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci.

Pope NJ, Bresnick EH.

Nucleic Acids Res. 2010 Apr;38(7):2190-200. doi: 10.1093/nar/gkp1159. Epub 2010 Jan 4.


Establishing a hematopoietic genetic network through locus-specific integration of chromatin regulators.

DeVilbiss AW, Boyer ME, Bresnick EH.

Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3398-407. doi: 10.1073/pnas.1302771110. Epub 2013 Aug 19.


The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220.

Stumpf M, Waskow C, Krötschel M, van Essen D, Rodriguez P, Zhang X, Guyot B, Roeder RG, Borggrefe T.

Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18504-9. Epub 2006 Nov 28. Erratum in: Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1442.


CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function.

Mizuta S, Minami T, Fujita H, Kaminaga C, Matsui K, Ishino R, Fujita A, Oda K, Kawai A, Hasegawa N, Urahama N, Roeder RG, Ito M.

Genes Cells. 2014 Jan;19(1):28-51. doi: 10.1111/gtc.12104. Epub 2013 Nov 19.


Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1.

Stumpf M, Yue X, Schmitz S, Luche H, Reddy JK, Borggrefe T.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21541-6. doi: 10.1073/pnas.1005794107. Epub 2010 Nov 23.


A regulatory circuit comprising GATA1/2 switch and microRNA-27a/24 promotes erythropoiesis.

Wang F, Zhu Y, Guo L, Dong L, Liu H, Yin H, Zhang Z, Li Y, Liu C, Ma Y, Song W, He A, Wang Q, Wang L, Zhang J, Li J, Yu J.

Nucleic Acids Res. 2014 Jan;42(1):442-57. doi: 10.1093/nar/gkt848. Epub 2013 Sep 18.


A regulatory network governing Gata1 and Gata2 gene transcription orchestrates erythroid lineage differentiation.

Moriguchi T, Yamamoto M.

Int J Hematol. 2014 Nov;100(5):417-24. doi: 10.1007/s12185-014-1568-0. Epub 2014 Mar 18. Review.


The mediator complex subunit 1 enhances transcription of genes needed for adrenal androgen production.

Nakamura Y, Xing Y, Sasano H, Rainey WE.

Endocrinology. 2009 Sep;150(9):4145-53. doi: 10.1210/en.2009-0006. Epub 2009 Jun 4.


The transcriptional mediator subunit MED1/TRAP220 in stromal cells is involved in hematopoietic stem/progenitor cell support through osteopontin expression.

Sumitomo A, Ishino R, Urahama N, Inoue K, Yonezawa K, Hasegawa N, Horie O, Matsuoka H, Kondo T, Roeder RG, Ito M.

Mol Cell Biol. 2010 Oct;30(20):4818-27. doi: 10.1128/MCB.01348-09. Epub 2010 Aug 16.


Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation.

Tanimura N, Miller E, Igarashi K, Yang D, Burstyn JN, Dewey CN, Bresnick EH.

EMBO Rep. 2016 Feb;17(2):249-65. doi: 10.15252/embr.201541465. Epub 2015 Dec 23.


The exosome complex establishes a barricade to erythroid maturation.

McIver SC, Kang YA, DeVilbiss AW, O'Driscoll CA, Ouellette JN, Pope NJ, Camprecios G, Chang CJ, Yang D, Bouhassira EE, Ghaffari S, Bresnick EH.

Blood. 2014 Oct 2;124(14):2285-97. doi: 10.1182/blood-2014-04-571083. Epub 2014 Aug 12.


Epigenetic Determinants of Erythropoiesis: Role of the Histone Methyltransferase SetD8 in Promoting Erythroid Cell Maturation and Survival.

DeVilbiss AW, Sanalkumar R, Hall BD, Katsumura KR, de Andrade IF, Bresnick EH.

Mol Cell Biol. 2015 Jun;35(12):2073-87. doi: 10.1128/MCB.01422-14. Epub 2015 Apr 8.


Relocalizing genetic loci into specific subnuclear neighborhoods.

Lee HY, Johnson KD, Boyer ME, Bresnick EH.

J Biol Chem. 2011 May 27;286(21):18834-44. doi: 10.1074/jbc.M111.221481. Epub 2011 Mar 11.


Building multifunctionality into a complex containing master regulators of hematopoiesis.

Fujiwara T, Lee HY, Sanalkumar R, Bresnick EH.

Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20429-34. doi: 10.1073/pnas.1007804107. Epub 2010 Nov 8.


The transcriptional coactivator DRIP/mediator complex is involved in vitamin D receptor function and regulates keratinocyte proliferation and differentiation.

Oda Y, Chalkley RJ, Burlingame AL, Bikle DD.

J Invest Dermatol. 2010 Oct;130(10):2377-88. doi: 10.1038/jid.2010.148. Epub 2010 Jun 3.


GATA factor switching during erythroid differentiation.

Kaneko H, Shimizu R, Yamamoto M.

Curr Opin Hematol. 2010 May;17(3):163-8. doi: 10.1097/MOH.0b013e32833800b8. Review.


FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment.

Gregory GD, Miccio A, Bersenev A, Wang Y, Hong W, Zhang Z, Poncz M, Tong W, Blobel GA.

Blood. 2010 Mar 18;115(11):2156-66. doi: 10.1182/blood-2009-10-251280. Epub 2010 Jan 11.


GATA-1 directly regulates p21 gene expression during erythroid differentiation.

Papetti M, Wontakal SN, Stopka T, Skoultchi AI.

Cell Cycle. 2010 May 15;9(10):1972-80. Epub 2010 May 15.

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