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Items: 1 to 20 of 96

1.

Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study.

Choquet H, Joslyn G, Lee A, Kasberger J, Robertson M, Brush G, Schuckit MA, White R, Jorgenson E.

Alcohol Clin Exp Res. 2013 Aug;37(8):1311-6. doi: 10.1111/acer.12099. Epub 2013 Mar 4.

PMID:
23458267
2.

The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

Lubke GH, Stephens SH, Lessem JM, Hewitt JK, Ehringer MA.

Behav Genet. 2012 Jul;42(4):636-46. doi: 10.1007/s10519-012-9529-y. Epub 2012 Mar 1.

3.

Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.

Li MD, Yoon D, Lee JY, Han BG, Niu T, Payne TJ, Ma JZ, Park T.

PLoS One. 2010 Aug 16;5(8):e12183. doi: 10.1371/journal.pone.0012183.

4.

An association study on the CHRNA5/A3/B4 gene cluster, smoking and psoriasis vulgaris.

Zhu KJ, Liu Z, Liu H, Li SJ, Zhu CY, Li KS, Fan YM.

Arch Dermatol Res. 2014 Dec;306(10):939-44. doi: 10.1007/s00403-014-1510-6. Epub 2014 Oct 9.

PMID:
25297392
5.

Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.

Li MD, Xu Q, Lou XY, Payne TJ, Niu T, Ma JZ.

Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 5;153B(3):745-56. doi: 10.1002/ajmg.b.31043.

6.

CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users.

Zhu AZ, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF.

Addiction. 2013 Oct;108(10):1818-28. doi: 10.1111/add.12250. Epub 2013 Jul 5.

7.

Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism.

Wen L, Jiang K, Yuan W, Cui W, Li MD.

Mol Neurobiol. 2016 Jan;53(1):472-484. doi: 10.1007/s12035-014-8997-x. Epub 2014 Dec 5. Review.

PMID:
25471942
8.

Association of CHRNA5-A3-B4 variation with esophageal squamous cell carcinoma risk and smoking behaviors in a Chinese population.

Wang Y, Wu H, Liu Q, Wang C, Fu L, Wang H, Zhu W, Fu W, Lv Y, Wang S, Hu L.

PLoS One. 2013 Jul 2;8(7):e67664. doi: 10.1371/journal.pone.0067664. Print 2013.

9.

Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.

Gallego X, Molas S, Amador-Arjona A, Marks MJ, Robles N, Murtra P, Armengol L, Fernández-Montes RD, Gratacòs M, Pumarola M, Cabrera R, Maldonado R, Sabrià J, Estivill X, Dierssen M.

Amino Acids. 2012 Aug;43(2):897-909. doi: 10.1007/s00726-011-1149-y. Epub 2011 Nov 19.

PMID:
22101982
10.

Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes.

Chen LS, Xian H, Grucza RA, Saccone NL, Wang JC, Johnson EO, Breslau N, Hatsukami D, Bierut LJ.

Drug Alcohol Depend. 2012 Jun;123 Suppl 1:S42-51. doi: 10.1016/j.drugalcdep.2012.01.014. Epub 2012 Feb 13.

11.

Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking.

Tyndale RF, Zhu AZ, George TP, Cinciripini P, Hawk LW Jr, Schnoll RA, Swan GE, Benowitz NL, Heitjan DF, Lerman C; PGRN-PNAT Research Group.

PLoS One. 2015 May 26;10(5):e0128109. doi: 10.1371/journal.pone.0128109. eCollection 2015.

12.

Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance.

Winterer G, Mittelstrass K, Giegling I, Lamina C, Fehr C, Brenner H, Breitling LP, Nitz B, Raum E, Müller H, Gallinat J, Gal A, Heim K, Prokisch H, Meitinger T, Hartmann AM, Möller HJ, Gieger C, Wichmann HE, Illig T, Dahmen N, Rujescu D.

Am J Med Genet B Neuropsychiatr Genet. 2010 Dec 5;153B(8):1448-58. doi: 10.1002/ajmg.b.31126. Epub 2010 Sep 30.

PMID:
20886544
13.

Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk.

Wassenaar CA, Dong Q, Wei Q, Amos CI, Spitz MR, Tyndale RF.

J Natl Cancer Inst. 2011 Sep 7;103(17):1342-6. doi: 10.1093/jnci/djr237. Epub 2011 Jul 11.

14.

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.

Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, Budde JP, Fox L, Goldstein E, Reyes O, Saccone N, Saccone S, Xuei X, Bucholz K, Kuperman S, Nurnberger J Jr, Rice JP, Schuckit M, Tischfield J, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate AM.

Mol Psychiatry. 2009 May;14(5):501-10. doi: 10.1038/mp.2008.42. Epub 2008 Apr 15.

15.

Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence.

Haller G, Druley T, Vallania FL, Mitra RD, Li P, Akk G, Steinbach JH, Breslau N, Johnson E, Hatsukami D, Stitzel J, Bierut LJ, Goate AM.

Hum Mol Genet. 2012 Feb 1;21(3):647-55. doi: 10.1093/hmg/ddr498. Epub 2011 Oct 31.

16.

Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans.

Olfson E, Saccone NL, Johnson EO, Chen LS, Culverhouse R, Doheny K, Foltz SM, Fox L, Gogarten SM, Hartz S, Hetrick K, Laurie CC, Marosy B, Amin N, Arnett D, Barr RG, Bartz TM, Bertelsen S, Borecki IB, Brown MR, Chasman DI, van Duijn CM, Feitosa MF, Fox ER, Franceschini N, Franco OH, Grove ML, Guo X, Hofman A, Kardia SL, Morrison AC, Musani SK, Psaty BM, Rao DC, Reiner AP, Rice K, Ridker PM, Rose LM, Schick UM, Schwander K, Uitterlinden AG, Vojinovic D, Wang JC, Ware EB, Wilson G, Yao J, Zhao W, Breslau N, Hatsukami D, Stitzel JA, Rice J, Goate A, Bierut LJ.

Mol Psychiatry. 2016 May;21(5):601-7. doi: 10.1038/mp.2015.105. Epub 2015 Aug 4.

17.

Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility.

Zhang H, Kranzler HR, Poling J, Gelernter J.

Neuropsychopharmacology. 2010 Oct;35(11):2211-24. doi: 10.1038/npp.2010.95. Epub 2010 Jul 14.

18.

The CHRNA5-A3-B4 Gene Cluster and Smoking: From Discovery to Therapeutics.

Lassi G, Taylor AE, Timpson NJ, Kenny PJ, Mather RJ, Eisen T, Munafò MR.

Trends Neurosci. 2016 Dec;39(12):851-861. doi: 10.1016/j.tins.2016.10.005. Epub 2016 Nov 18. Review.

19.

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes.

Baker TB, Weiss RB, Bolt D, von Niederhausern A, Fiore MC, Dunn DM, Piper ME, Matsunami N, Smith SS, Coon H, McMahon WM, Scholand MB, Singh N, Hoidal JR, Kim SY, Leppert MF, Cannon DS.

Nicotine Tob Res. 2009 Jul;11(7):785-96. doi: 10.1093/ntr/ntp064. Epub 2009 May 12.

20.

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF, Grucza RA, Sun L, Duan W, Budde J, Culverhouse RC, Fox L, Hinrichs AL, Steinbach JH, Wu M, Rice JP, Goate AM, Bierut LJ.

Cancer Res. 2009 Sep 1;69(17):6848-56. doi: 10.1158/0008-5472.CAN-09-0786. Epub 2009 Aug 25.

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