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Items: 1 to 20 of 101

1.

Rational design, synthesis and QSAR study of vasorelaxant active 3-pyridinecarbonitriles incorporating 1H-benzimidazol-2-yl function.

Nofal ZM, Srour AM, El-Eraky WI, Saleh DO, Girgis AS.

Eur J Med Chem. 2013 May;63:14-21. doi: 10.1016/j.ejmech.2013.01.042.

PMID:
23454530
2.

Synthesis and vasodilation activity of some novel bis(3-pyridinecarbonitrile) derivatives.

Barsoum FF.

Eur J Med Chem. 2010 Nov;45(11):5176-82. doi: 10.1016/j.ejmech.2010.08.032.

PMID:
20828883
3.

Facile synthesis, vasorelaxant properties and molecular modeling studies of 2-amino-8a-methoxy-4H-pyrano[3,2-c]pyridine-3-carbonitriles.

Girgis AS, Ismail NS, Farag H.

Eur J Med Chem. 2011 Jun;46(6):2397-407. doi: 10.1016/j.ejmech.2011.03.023.

PMID:
21489662
4.

Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties.

Girgis AS, Mishriky N, Farag AM, El-Eraky WI, Farag H.

Eur J Med Chem. 2008 Sep;43(9):1818-27. doi: 10.1016/j.ejmech.2007.11.025.

PMID:
18241958
5.

Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives.

George RF, Saleh DO.

Eur J Med Chem. 2016 Jan 27;108:663-73. doi: 10.1016/j.ejmech.2015.12.015.

PMID:
26735908
6.
7.

Identification of SVM-based classification model, synthesis and evaluation of prenylated flavonoids as vasorelaxant agents.

Dong X, Liu Y, Yan J, Jiang C, Chen J, Liu T, Hu Y.

Bioorg Med Chem. 2008 Sep 1;16(17):8151-60. doi: 10.1016/j.bmc.2008.07.031.

PMID:
18678502
8.

Design, synthesis and vasodilative activity of tanshinone IIA derivatives.

Bi YF, Wang ZJ, Guan RF, Ye YT, Chen YY, Zhang YB, Liu HM.

Bioorg Med Chem Lett. 2012 Aug 1;22(15):5141-3. doi: 10.1016/j.bmcl.2012.05.014.

PMID:
22765898
9.

Design, synthesis, and biological evaluation of prenylated chalcones as vasorelaxant agents.

Dong X, Chen J, Jiang C, Liu T, Hu Y.

Arch Pharm (Weinheim). 2009 Jul;342(7):428-32. doi: 10.1002/ardp.200800229.

PMID:
19544479
10.

Vasorelaxant effects of Acer nikoense extract and isolated coumarinolignans on rat aortic rings.

Iizuka T, Nagumo S, Yotsumoto H, Moriyama H, Nagai M.

Biol Pharm Bull. 2007 Jun;30(6):1164-6.

11.

Synthesis, biological evaluation and structure-activity relationships of new phthalazinedione derivatives with vasorelaxant activity.

Munín J, Quezada E, Cuiñas A, Campos-Toimil M, Uriarte E, Santana L, Viña D.

Eur J Med Chem. 2014 Jul 23;82:407-17. doi: 10.1016/j.ejmech.2014.05.052.

PMID:
24929291
12.

Regioselective synthesis and molecular modeling study of vasorelaxant active 7,9-dioxa-1,2-diaza-spiro[4.5]dec-2-ene-6,10-diones.

Girgis AS, Ismail NS, Farag H, el-Eraky WI, Saleh DO, Tala SR, Katritzky AR.

Eur J Med Chem. 2010 Sep;45(9):4229-38. doi: 10.1016/j.ejmech.2010.06.018.

PMID:
20615586
13.

Relaxant activity of 2-(substituted phenyl)-1H-benzimidazoles on isolated rat aortic rings: design and synthesis of 5-nitro derivatives.

Estrada-Soto S, Villalobos-Molina R, Aguirre-Crespo F, Vergara-Galicia J, Moreno-Díaz H, Torres-Piedra M, Navarrete-Vázquez G.

Life Sci. 2006 Jun 27;79(5):430-5.

PMID:
16487544
14.

Design, synthesis and vasorelaxant evaluation of novel coumarin-pyrimidine hybrids.

Amin KM, Awadalla FM, Eissa AA, Abou-Seri SM, Hassan GS.

Bioorg Med Chem. 2011 Oct 15;19(20):6087-97. doi: 10.1016/j.bmc.2011.08.037.

PMID:
21908192
15.

Synthesis and quantitative structure activity relationship (QSAR) of arylidene (benzimidazol-1-yl)acetohydrazones as potential antibacterial agents.

El-Kilany Y, Nahas NM, Al-Ghamdi MA, Badawy ME, El Ashry el SH.

World J Microbiol Biotechnol. 2015 Jan;31(1):145-52. doi: 10.1007/s11274-014-1755-4.

PMID:
25304024
16.

[Vasorelaxant effect of sulfur dioxide derivatives on isolated aortic rings of rats and its mechanisms].

Du SX, Zhang CY, Jin HF, Du JB, Tang CS.

Beijing Da Xue Xue Bao. 2006 Dec 18;38(6):581-5. Chinese.

17.

Vasodilatory activity and antihypertensive profile mediated by inhibition of phosphodiesterase type 1 induced by a novel sulfonamide compound.

Pontes LB, Antunes F, Sudo RT, Raimundo JM, Lima LM, Barreiro EJ, Zapata-Sudo G.

Fundam Clin Pharmacol. 2012 Dec;26(6):690-700. doi: 10.1111/j.1472-8206.2011.00999.x.

PMID:
22066694
18.
19.

Synthesis and vasorelaxant activity of 4-(cyclic amido)-2H-naphtho[1,2-b]pyrans.

Chiou WF, Li SY, Ho LK, Hsien ML, Don MJ.

Eur J Med Chem. 2002 Jan;37(1):69-75.

PMID:
11841876
20.

A new isoquinolinone derivative with noble vasorelaxation activity.

Lin CH, Lin MS, Lin YH, Chen IM, Lin PR, Cheng CY, Tsai MC.

Pharmacology. 2003 Apr;67(4):202-10.

PMID:
12595751

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