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Items: 1 to 20 of 362

1.

Synthesis of indazole based diarylurea derivatives and their antiproliferative activity against tumor cell lines.

Zhao CR, Wang RQ, Li G, Xue XX, Sun CJ, Qu XJ, Li WB.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):1989-92. doi: 10.1016/j.bmcl.2013.02.034. Epub 2013 Feb 15.

PMID:
23454017
2.

Rational drug design of indazole-based diarylurea derivatives as anticancer agents.

Chu YY, Cheng HJ, Tian ZH, Zhao JC, Li G, Chu YY, Sun CJ, Li WB.

Chem Biol Drug Des. 2017 Oct;90(4):609-617. doi: 10.1111/cbdd.12984. Epub 2017 May 2.

PMID:
28338292
3.

Design, synthesis and evaluation of novel diaryl urea derivatives as potential antitumor agents.

Lu C, Tang K, Li Y, Li P, Lin Z, Yin D, Chen X, Huang H.

Eur J Med Chem. 2014 Apr 22;77:351-60. doi: 10.1016/j.ejmech.2014.03.020. Epub 2014 Mar 12.

PMID:
24675135
4.

Synthesis and antiproliferative assay of 1,3,4-oxadiazole and 1,2,4-triazole derivatives in cancer cells.

Tu G, Yan Y, Chen X, Lv Q, Wang J, Li S.

Drug Discov Ther. 2013 Apr;7(2):58-65.

5.

Synthesis and antiproliferative activity of novel diaryl ureas possessing a 4H-pyrido[1,2-a]pyrimidin-4-one group.

Yao P, Zhai X, Liu D, Qi BH, Tan HL, Jin YC, Gong P.

Arch Pharm (Weinheim). 2010 Jan;343(1):17-23. doi: 10.1002/ardp.200900130.

PMID:
19927308
6.

Synthesis and in vitro antitumor activities of novel benzyl urea analogues of sorafenib.

Lu CS, Tang K, Li Y, Jin B, Yin DL, Ma C, Chen XG, Huang HH.

Yao Xue Xue Bao. 2013 May;48(5):709-17.

PMID:
23888694
7.

Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.

Jung MH, Kim H, Choi WK, El-Gamal MI, Park JH, Yoo KH, Sim TB, Lee SH, Baek D, Hah JM, Cho JH, Oh CH.

Bioorg Med Chem Lett. 2009 Dec 1;19(23):6538-43. doi: 10.1016/j.bmcl.2009.10.051. Epub 2009 Oct 15.

PMID:
19857963
8.

Design and synthesis of 2-iminothiazolidin-4-one moiety-containing compounds as potent antiproliferative agents.

Zhai X, Li W, Chen D, Lai R, Liu J, Gong P.

Arch Pharm (Weinheim). 2012 May;345(5):360-7. doi: 10.1002/ardp.201100064. Epub 2012 Jan 2.

PMID:
22223396
9.

Synthesis and broad-spectrum antiproliferative activity of diarylamides and diarylureas possessing 1,3,4-oxadiazole derivatives.

Gamal El-Din MM, El-Gamal MI, Abdel-Maksoud MS, Yoo KH, Oh CH.

Bioorg Med Chem Lett. 2015 Apr 15;25(8):1692-1699. doi: 10.1016/j.bmcl.2015.03.001. Epub 2015 Mar 7.

PMID:
25801936
10.

Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents.

Arafa RK, Hegazy GH, Piazza GA, Abadi AH.

Eur J Med Chem. 2013 May;63:826-32. doi: 10.1016/j.ejmech.2013.03.008. Epub 2013 Mar 16.

PMID:
23584545
11.

Design, synthesis and biological activities of sorafenib derivatives as antitumor agents.

Yao J, He Z, Chen J, Sun W, Fang H, Xu W.

Bioorg Med Chem Lett. 2012 Nov 1;22(21):6549-53. doi: 10.1016/j.bmcl.2012.09.031. Epub 2012 Sep 19.

PMID:
23021967
12.

Synthesis of substituted 3-amino-N-phenyl-1H-indazole-1-carboxamides endowed with antiproliferative activity.

Maggio B, Raimondi MV, Raffa D, Plescia F, Cascioferro S, Plescia S, Tolomeo M, Di Cristina A, Pipitone RM, Grimaudo S, Daidone G.

Eur J Med Chem. 2011 Jan;46(1):168-74. doi: 10.1016/j.ejmech.2010.10.032. Epub 2010 Nov 10.

PMID:
21130540
13.

Design, synthesis and structure-activity relationships of antiproliferative 1,3-disubstituted urea derivatives.

Li HQ, Zhu TT, Yan T, Luo Y, Zhu HL.

Eur J Med Chem. 2009 Feb;44(2):453-9. doi: 10.1016/j.ejmech.2008.04.011. Epub 2008 Apr 30.

PMID:
18514972
14.

Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives.

Fu W, Wang J, Yu L, Zhao L, Lu N, You Q, Guo Q, Li Z.

Bioorg Med Chem Lett. 2012 Jan 15;22(2):1118-21. doi: 10.1016/j.bmcl.2011.11.117. Epub 2011 Dec 6.

PMID:
22196122
15.

Synthesis of 1H-pyrazole-1-carboxamide derivatives and their antiproliferative activity against melanoma cell line.

El-Gamal MI, Sim TB, Hong JH, Cho JH, Yoo KH, Oh CH.

Arch Pharm (Weinheim). 2011 Mar;344(3):197-204. doi: 10.1002/ardp.201000057. Epub 2010 Dec 27.

PMID:
21384419
16.

Design, synthesis and antiproliferative activity studies of novel 1,2,3-triazole-dithiocarbamate-urea hybrids.

Duan YC, Zheng YC, Li XC, Wang MM, Ye XW, Guan YY, Liu GZ, Zheng JX, Liu HM.

Eur J Med Chem. 2013 Jun;64:99-110. doi: 10.1016/j.ejmech.2013.03.058. Epub 2013 Apr 6.

PMID:
23644193
17.

Synthesis and biological evaluation of novel 6-hydrazinyl-2,4-bismorpholino pyrimidine and 1,3,5-triazine derivatives as potential antitumor agents.

Zhu W, Liu Y, Zhao Y, Wang H, Tan L, Fan W, Gong P.

Arch Pharm (Weinheim). 2012 Oct;345(10):812-21. doi: 10.1002/ardp.201200074. Epub 2012 Jun 18.

PMID:
22707438
18.

Design, synthesis, and antiproliferative activity of new 1H-pyrrolo[3,2-c]pyridine derivatives against melanoma cell lines.

El-Gamal MI, Jung MH, Lee WS, Sim T, Yoo KH, Oh CH.

Eur J Med Chem. 2011 Aug;46(8):3218-26. doi: 10.1016/j.ejmech.2011.04.031. Epub 2011 Apr 16.

PMID:
21592628
19.

Design and synthesis of new RAF kinase-inhibiting antiproliferative quinoline derivatives. Part 2: Diarylurea derivatives.

El-Gamal MI, Khan MA, Tarazi H, Abdel-Maksoud MS, Gamal El-Din MM, Yoo KH, Oh CH.

Eur J Med Chem. 2017 Feb 15;127:413-423. doi: 10.1016/j.ejmech.2017.01.006. Epub 2017 Jan 5.

PMID:
28088086
20.

Design, synthesis and evaluation of novel rhodanine-containing sorafenib analogs as potential antitumor agents.

Li W, Zhai X, Zhong Z, Li G, Pu Y, Gong P.

Arch Pharm (Weinheim). 2011 Jun;344(6):349-57. doi: 10.1002/ardp.201000326. Epub 2011 Mar 24.

PMID:
21433057

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