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Items: 1 to 20 of 1088

1.

Antioxidant effects of diallyl trisulfide on high glucose-induced apoptosis are mediated by the PI3K/Akt-dependent activation of Nrf2 in cardiomyocytes.

Tsai CY, Wang CC, Lai TY, Tsu HN, Wang CH, Liang HY, Kuo WW.

Int J Cardiol. 2013 Sep 30;168(2):1286-97. doi: 10.1016/j.ijcard.2012.12.004. Epub 2013 Feb 27.

PMID:
23453443
2.

Diallyl trisufide (DATS) suppresses high glucose-induced cardiomyocyte apoptosis by inhibiting JNK/NFκB signaling via attenuating ROS generation.

Kuo WW, Wang WJ, Tsai CY, Way CL, Hsu HH, Chen LM.

Int J Cardiol. 2013 Sep 20;168(1):270-80. doi: 10.1016/j.ijcard.2012.09.080. Epub 2012 Nov 13.

PMID:
23158927
3.

Diallyl trisufide protects against oxygen glucose deprivation -induced apoptosis by scavenging free radicals via the PI3K/Akt -mediated Nrf2/HO-1 signaling pathway in B35 neural cells.

Xu XH, Li GL, Wang BA, Qin Y, Bai SR, Rong J, Deng T, Li Q.

Brain Res. 2015 Jul 21;1614:38-50. doi: 10.1016/j.brainres.2015.04.014. Epub 2015 Apr 17.

PMID:
25896937
4.

Diallyl trisulfide protects against high glucose-induced cardiac apoptosis by stimulating the production of cystathionine gamma-lyase-derived hydrogen sulfide.

Tsai CY, Wen SY, Shibu MA, Yang YC, Peng H, Wang B, Wei YM, Chang HY, Lee CY, Huang CY, Kuo WW.

Int J Cardiol. 2015 Sep 15;195:300-10. doi: 10.1016/j.ijcard.2015.05.111. Epub 2015 May 20.

PMID:
26056963
5.

Keap1 cysteine 288 as a potential target for diallyl trisulfide-induced Nrf2 activation.

Kim S, Lee HG, Park SA, Kundu JK, Keum YS, Cha YN, Na HK, Surh YJ.

PLoS One. 2014 Jan 28;9(1):e85984. doi: 10.1371/journal.pone.0085984. eCollection 2014.

6.

Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals.

Chen C, Pung D, Leong V, Hebbar V, Shen G, Nair S, Li W, Kong AN.

Free Radic Biol Med. 2004 Nov 15;37(10):1578-90.

PMID:
15477009
7.

Diallyl trisulfide-induced apoptosis of bladder cancer cells is caspase-dependent and regulated by PI3K/Akt and JNK pathways.

Shin DY, Kim GY, Hwang HJ, Kim WJ, Choi YH.

Environ Toxicol Pharmacol. 2014 Jan;37(1):74-83. doi: 10.1016/j.etap.2013.11.002. Epub 2013 Nov 9.

PMID:
24309133
8.

The protective effects of endogenous hydrogen sulfide modulator, S-propargyl-cysteine, on high glucose-induced apoptosis in cardiomyocytes: A novel mechanism mediated by the activation of Nrf2.

Yang H, Mao Y, Tan B, Luo S, Zhu Y.

Eur J Pharmacol. 2015 Aug 15;761:135-43. doi: 10.1016/j.ejphar.2015.05.001. Epub 2015 May 12.

PMID:
25979858
9.

The involvement of Nrf2 in the protective effects of diallyl disulfide on carbon tetrachloride-induced hepatic oxidative damage and inflammatory response in rats.

Lee IC, Kim SH, Baek HS, Moon C, Kang SS, Kim SH, Kim YB, Shin IS, Kim JC.

Food Chem Toxicol. 2014 Jan;63:174-85. doi: 10.1016/j.fct.2013.11.006. Epub 2013 Nov 15.

PMID:
24246655
11.

Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1.

Na HK, Kim EH, Choi MA, Park JM, Kim DH, Surh YJ.

Biochem Pharmacol. 2012 Nov 15;84(10):1241-50. doi: 10.1016/j.bcp.2012.08.024. Epub 2012 Sep 6.

PMID:
22981381
12.

Diallyl trisulfide induces osteosarcoma cell apoptosis through reactive oxygen species-mediated downregulation of the PI3K/Akt pathway.

Wang H, Sun N, Li X, Li K, Tian J, Li J.

Oncol Rep. 2016 Jun;35(6):3648-58. doi: 10.3892/or.2016.4722. Epub 2016 Apr 1.

PMID:
27035545
13.

Effect of diallyl sulfide on in vitro and in vivo Nrf2-mediated pulmonic antioxidant enzyme expression via activation ERK/p38 signaling pathway.

Ho CY, Cheng YT, Chau CF, Yen GC.

J Agric Food Chem. 2012 Jan 11;60(1):100-7. doi: 10.1021/jf203800d. Epub 2011 Dec 13.

PMID:
22118872
14.

Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2.

Xiao D, Choi S, Johnson DE, Vogel VG, Johnson CS, Trump DL, Lee YJ, Singh SV.

Oncogene. 2004 Jul 22;23(33):5594-606.

PMID:
15184882
15.

Myricitrin Attenuates High Glucose-Induced Apoptosis through Activating Akt-Nrf2 Signaling in H9c2 Cardiomyocytes.

Zhang B, Chen Y, Shen Q, Liu G, Ye J, Sun G, Sun X.

Molecules. 2016 Jul 5;21(7). pii: E880. doi: 10.3390/molecules21070880.

16.

Antioxidant effects of hydrogen sulfide on left ventricular remodeling in smoking rats are mediated via PI3K/Akt-dependent activation of Nrf2.

Zhou X, Zhao L, Mao J, Huang J, Chen J.

Toxicol Sci. 2015 Mar;144(1):197-203. doi: 10.1093/toxsci/kfu272. Epub 2014 Dec 16.

PMID:
25516494
18.

Apoptosis induction in human lung adenocarcinoma cells by oil-soluble allyl sulfides: triggers, pathways, and modulators.

Wu XJ, Hu Y, Lamy E, Mersch-Sundermann V.

Environ Mol Mutagen. 2009 Apr;50(3):266-75. doi: 10.1002/em.20467.

PMID:
19197990
19.

Diallyl trisulfide and diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats.

Huang YT, Yao CH, Way CL, Lee KW, Tsai CY, Ou HC, Kuo WW.

J Appl Physiol (1985). 2013 Feb;114(3):402-10. doi: 10.1152/japplphysiol.00672.2012. Epub 2012 Nov 8.

20.

Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.

Fisher CD, Augustine LM, Maher JM, Nelson DM, Slitt AL, Klaassen CD, Lehman-McKeeman LD, Cherrington NJ.

Drug Metab Dispos. 2007 Jun;35(6):995-1000. Epub 2007 Mar 12.

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