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Items: 1 to 20 of 114

1.

Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina.

Gramlich OW, Beck S, von Thun Und Hohenstein-Blaul N, Boehm N, Ziegler A, Vetter JM, Pfeiffer N, Grus FH.

PLoS One. 2013;8(2):e57557. doi: 10.1371/journal.pone.0057557. Epub 2013 Feb 25.

2.

Does autoimmunity play a part in the pathogenesis of glaucoma?

Bell K, Gramlich OW, Von Thun Und Hohenstein-Blaul N, Beck S, Funke S, Wilding C, Pfeiffer N, Grus FH.

Prog Retin Eye Res. 2013 Sep;36:199-216. doi: 10.1016/j.preteyeres.2013.02.003. Epub 2013 Mar 27. Review.

PMID:
23541978
3.

Biomarkers for glaucoma: from the lab to the clinic.

Von Thun Und Hohenstein-Blaul N, Kunst S, Pfeiffer N, Grus FH.

Eye (Lond). 2017 Feb;31(2):225-231. doi: 10.1038/eye.2016.300. Epub 2017 Jan 13.

PMID:
28085137
4.

Serum autoantibodies to alpha-fodrin are present in glaucoma patients from Germany and the United States.

Grus FH, Joachim SC, Bruns K, Lackner KJ, Pfeiffer N, Wax MB.

Invest Ophthalmol Vis Sci. 2006 Mar;47(3):968-76.

PMID:
16505031
6.

Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmune glaucoma.

Joachim SC, Reinehr S, Kuehn S, Laspas P, Gramlich OW, Kuehn M, Tischoff I, von Pein HD, Dick HB, Grus FH.

Mol Vis. 2013 Aug 6;19:1804-14. eCollection 2013.

7.

Analysis of autoantibodies against human retinal antigens in sera of patients with glaucoma and ocular hypertension.

Reichelt J, Joachim SC, Pfeiffer N, Grus FH.

Curr Eye Res. 2008 Mar;33(3):253-61. doi: 10.1080/02713680701871157.

PMID:
18350436
8.

Immune response after intermittent minimally invasive intraocular pressure elevations in an experimental animal model of glaucoma.

Gramlich OW, Teister J, Neumann M, Tao X, Beck S, von Pein HD, Pfeiffer N, Grus FH.

J Neuroinflammation. 2016 Apr 18;13(1):82. doi: 10.1186/s12974-016-0542-6.

9.

Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand.

Wax MB, Tezel G, Yang J, Peng G, Patil RV, Agarwal N, Sappington RM, Calkins DJ.

J Neurosci. 2008 Nov 12;28(46):12085-96. doi: 10.1523/JNEUROSCI.3200-08.2008.

10.

New insights into autoantibody profiles from immune privileged sites in the eye: a glaucoma study.

Boehm N, Wolters D, Thiel U, Lossbrand U, Wiegel N, Pfeiffer N, Grus FH.

Brain Behav Immun. 2012 Jan;26(1):96-102. doi: 10.1016/j.bbi.2011.07.241. Epub 2011 Aug 6.

PMID:
21843631
11.

Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens.

Joachim SC, Gramlich OW, Laspas P, Schmid H, Beck S, von Pein HD, Dick HB, Pfeiffer N, Grus FH.

PLoS One. 2012;7(7):e40616. doi: 10.1371/journal.pone.0040616. Epub 2012 Jul 26.

12.

Autoreactive antibodies and loss of retinal ganglion cells in rats induced by immunization with ocular antigens.

Laspas P, Gramlich OW, Müller HD, Cuny CS, Gottschling PF, Pfeiffer N, Dick HB, Joachim SC, Grus FH.

Invest Ophthalmol Vis Sci. 2011 Nov 11;52(12):8835-48. doi: 10.1167/iovs.10-6889.

PMID:
22003114
13.

Analysis of autoantibody repertoires in sera of patients with glaucoma.

Joachim SC, Grus FH, Pfeiffer N.

Eur J Ophthalmol. 2003 Nov-Dec;13(9-10):752-8.

PMID:
14700094
14.

Modulation of the immune system for the treatment of glaucoma.

Bell K, Und Hohenstein-Blaul NVT, Teister J, Grus FH.

Curr Neuropharmacol. 2017 Jul 19. doi: 10.2174/1570159X15666170720094529. [Epub ahead of print]

PMID:
28730968
15.

Serum autoantibody biomarkers for age-related macular degeneration and possible regulators of neovascularization.

Morohoshi K, Patel N, Ohbayashi M, Chong V, Grossniklaus HE, Bird AC, Ono SJ.

Exp Mol Pathol. 2012 Feb;92(1):64-73. doi: 10.1016/j.yexmp.2011.09.017. Epub 2011 Oct 6.

PMID:
22001380
16.

Autoimmune aspects in glaucoma.

Von Thun Und Hohenstein-Blaul N, Bell K, Pfeiffer N, Grus FH.

Eur J Pharmacol. 2016 Sep 15;787:105-18. doi: 10.1016/j.ejphar.2016.04.031. Epub 2016 Apr 14. Review.

PMID:
27090926
17.

Complex autoantibody repertoires in patients with glaucoma.

Grus FH, Joachim SC, Hoffmann EM, Pfeiffer N.

Mol Vis. 2004 Feb 25;10:132-7.

18.

IgG antibody patterns in aqueous humor of patients with primary open angle glaucoma and pseudoexfoliation glaucoma.

Joachim SC, Wuenschig D, Pfeiffer N, Grus FH.

Mol Vis. 2007 Sep 5;13:1573-9.

PMID:
17893658
19.

Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina.

Yang X, Luo C, Cai J, Powell DW, Yu D, Kuehn MH, Tezel G.

Invest Ophthalmol Vis Sci. 2011 Oct 31;52(11):8442-54. doi: 10.1167/iovs.11-8152.

20.

Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes.

Stasi K, Nagel D, Yang X, Wang RF, Ren L, Podos SM, Mittag T, Danias J.

Invest Ophthalmol Vis Sci. 2006 Mar;47(3):1024-9.

PMID:
16505037

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