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Items: 1 to 20 of 95

1.

Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor.

Suzuki M, Takaishi S, Nagasaki M, Onozawa Y, Iino I, Maeda H, Komai T, Oda T.

J Biol Chem. 2013 Apr 12;288(15):10684-91. doi: 10.1074/jbc.M112.420042. Epub 2013 Feb 28.

2.

Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84.

Wang J, Wu X, Simonavicius N, Tian H, Ling L.

J Biol Chem. 2006 Nov 10;281(45):34457-64. Epub 2006 Sep 11.

3.

Inflammatory changes in adipose tissue enhance expression of GPR84, a medium-chain fatty acid receptor: TNFα enhances GPR84 expression in adipocytes.

Nagasaki H, Kondo T, Fuchigami M, Hashimoto H, Sugimura Y, Ozaki N, Arima H, Ota A, Oiso Y, Hamada Y.

FEBS Lett. 2012 Feb 17;586(4):368-72. doi: 10.1016/j.febslet.2012.01.001. Epub 2012 Jan 10.

4.

Discovery and Characterization of a Novel Small-Molecule Agonist for Medium-Chain Free Fatty Acid Receptor G Protein-Coupled Receptor 84.

Zhang Q, Yang H, Li J, Xie X.

J Pharmacol Exp Ther. 2016 May;357(2):337-44. doi: 10.1124/jpet.116.232033. Epub 2016 Mar 9.

5.

Mutation analysis and molecular modeling for the investigation of ligand-binding modes of GPR84.

Nikaido Y, Koyama Y, Yoshikawa Y, Furuya T, Takeda S.

J Biochem. 2015 May;157(5):311-20. doi: 10.1093/jb/mvu075. Epub 2014 Nov 25.

PMID:
25425658
6.

A medium-chain fatty acid receptor Gpr84 in zebrafish: expression pattern and roles in immune regulation.

Huang Q, Feng D, Liu K, Wang P, Xiao H, Wang Y, Zhang S, Liu Z.

Dev Comp Immunol. 2014 Aug;45(2):252-8. doi: 10.1016/j.dci.2014.03.017. Epub 2014 Apr 1.

PMID:
24704214
7.

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

Pillaiyar T, Köse M, Sylvester K, Weighardt H, Thimm D, Borges G, Förster I, von Kügelgen I, Müller CE.

J Med Chem. 2017 May 11;60(9):3636-3655. doi: 10.1021/acs.jmedchem.6b01593. Epub 2017 May 1.

PMID:
28406627
8.

Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses.

Means TK, Jones BW, Schromm AB, Shurtleff BA, Smith JA, Keane J, Golenbock DT, Vogel SN, Fenton MJ.

J Immunol. 2001 Mar 15;166(6):4074-82.

11.

A benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor alpha production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation.

Mourey RJ, Burnette BL, Brustkern SJ, Daniels JS, Hirsch JL, Hood WF, Meyers MJ, Mnich SJ, Pierce BS, Saabye MJ, Schindler JF, South SA, Webb EG, Zhang J, Anderson DR.

J Pharmacol Exp Ther. 2010 Jun;333(3):797-807. doi: 10.1124/jpet.110.166173. Epub 2010 Mar 17.

12.

Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice.

Nagase M, Kurihara H, Aiba A, Young MJ, Sakai T.

PLoS One. 2016 Mar 3;11(3):e0150886. doi: 10.1371/journal.pone.0150886. eCollection 2016.

13.

Structural basis for inflammation-driven shedding of CD163 ectodomain and tumor necrosis factor-α in macrophages.

Etzerodt A, Rasmussen MR, Svendsen P, Chalaris A, Schwarz J, Galea I, Møller HJ, Moestrup SK.

J Biol Chem. 2014 Jan 10;289(2):778-88. doi: 10.1074/jbc.M113.520213. Epub 2013 Nov 25.

14.

Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction.

Kim J, Kwak HJ, Cha JY, Jeong YS, Rhee SD, Kim KR, Cheon HG.

J Biol Chem. 2014 Aug 15;289(33):23246-55. doi: 10.1074/jbc.M114.577908. Epub 2014 Jun 27.

15.

Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis.

Iwahashi M, Yamamura M, Aita T, Okamoto A, Ueno A, Ogawa N, Akashi S, Miyake K, Godowski PJ, Makino H.

Arthritis Rheum. 2004 May;50(5):1457-67.

16.

In vivo and in vitro roles of IL-21 in inflammation.

Pelletier M, Bouchard A, Girard D.

J Immunol. 2004 Dec 15;173(12):7521-30.

17.

Purinergic receptor regulation of LPS-induced signaling and pathophysiology.

Guerra AN, Fisette PL, Pfeiffer ZA, Quinchia-Rios BH, Prabhu U, Aga M, Denlinger LC, Guadarrama AG, Abozeid S, Sommer JA, Proctor RA, Bertics PJ.

J Endotoxin Res. 2003;9(4):256-63.

PMID:
12935357
18.

G protein-coupled receptor 84, a microglia-associated protein expressed in neuroinflammatory conditions.

Bouchard C, Pagé J, Bédard A, Tremblay P, Vallières L.

Glia. 2007 Jun;55(8):790-800.

PMID:
17390309
19.

Zinc finger protein 64 promotes Toll-like receptor-triggered proinflammatory and type I interferon production in macrophages by enhancing p65 subunit activation.

Wang C, Liu X, Liu Y, Zhang Q, Yao Z, Huang B, Zhang P, Li N, Cao X.

J Biol Chem. 2013 Aug 23;288(34):24600-8. doi: 10.1074/jbc.M113.473397. Epub 2013 Jul 15.

20.

Dialyzable leukocyte extract differentially regulates the production of TNFalpha, IL-6, and IL-8 in bacterial component-activated leukocytes and endothelial cells.

Ojeda MO, van't Veer C, Fernández Ortega CB, Araña Rosainz Mde J, Buurman WA.

Inflamm Res. 2005 Feb;54(2):74-81.

PMID:
15750714

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