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Items: 1 to 20 of 115

1.

Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters.

Hasegawa N, Abei M, Yokoyama KK, Fukuda K, Seo E, Kawashima R, Nakano Y, Yamada T, Nakade K, Hamada H, Obata Y, Hyodo I.

Int J Cancer. 2013 Sep 15;133(6):1479-88. doi: 10.1002/ijc.28132. Epub 2013 Apr 4.

2.

Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase: significance of timing of 5-fluorouracil administration.

Seo E, Abei M, Wakayama M, Fukuda K, Ugai H, Murata T, Todoroki T, Matsuzaki Y, Tanaka N, Hamada H, Yokoyama KK.

Cancer Res. 2005 Jan 15;65(2):546-52.

3.

Effect of preexisting immunity on oncolytic adenovirus vector INGN 007 antitumor efficacy in immunocompetent and immunosuppressed Syrian hamsters.

Dhar D, Spencer JF, Toth K, Wold WS.

J Virol. 2009 Mar;83(5):2130-9. doi: 10.1128/JVI.02127-08. Epub 2008 Dec 10.

4.
5.

Enhanced therapeutic effect using sequential administration of antigenically distinct oncolytic viruses expressing oncostatin M in a Syrian hamster orthotopic pancreatic cancer model.

Nistal-Villan E, Bunuales M, Poutou J, Gonzalez-Aparicio M, Bravo-Perez C, Quetglas JI, Carte B, Gonzalez-Aseguinolaza G, Prieto J, Larrea E, Hernandez-Alcoceba R.

Mol Cancer. 2015 Dec 16;14:210. doi: 10.1186/s12943-015-0479-x.

6.

Gene therapy for intraperitoneally disseminated pancreatic cancers by Escherichia coli uracil phosphoribosiltransferase (UPRT) gene mediated by restricted replication-competent adenoviral vectors.

Oonuma M, Sunamura M, Motoi F, Fukuyama S, Shimamura H, Yamauchi J, Shibuya K, Egawa S, Hamada H, Takeda K, Matsuno S.

Int J Cancer. 2002 Nov 1;102(1):51-9.

7.

A novel therapeutic regimen to eradicate established solid tumors with an effective induction of tumor-specific immunity.

Tysome JR, Li X, Wang S, Wang P, Gao D, Du P, Chen D, Gangeswaran R, Chard LS, Yuan M, Alusi G, Lemoine NR, Wang Y.

Clin Cancer Res. 2012 Dec 15;18(24):6679-89. doi: 10.1158/1078-0432.CCR-12-0979. Epub 2012 Oct 22.

8.

The role of cyclophosphamide in enhancing antitumor efficacy of an adenovirus oncolytic vector in subcutaneous Syrian hamster tumors.

Young BA, Spencer JF, Ying B, Tollefson AE, Toth K, Wold WS.

Cancer Gene Ther. 2013 Sep;20(9):521-30. doi: 10.1038/cgt.2013.49. Epub 2013 Aug 9.

9.

Adenovirus-mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene increases the sensitivity of esophageal cancer cells to 5-fluorouracil.

Nakamura H, Sekiguchi H, Akiyama S, Hamada H, Fujiwara M, Kasai Y, Ito K, Nakao A.

Surg Today. 2001;31(9):785-90.

PMID:
11686556
10.

Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression.

Rodríguez-García A, Giménez-Alejandre M, Rojas JJ, Moreno R, Bazan-Peregrino M, Cascalló M, Alemany R.

Clin Cancer Res. 2015 Mar 15;21(6):1406-18. doi: 10.1158/1078-0432.CCR-14-2213. Epub 2014 Nov 12.

11.

Immunosuppression enhances oncolytic adenovirus replication and antitumor efficacy in the Syrian hamster model.

Thomas MA, Spencer JF, Toth K, Sagartz JE, Phillips NJ, Wold WS.

Mol Ther. 2008 Oct;16(10):1665-73. doi: doi:10.1038/mt.2008.162. Epub 2008 Jul 29.

12.

Potent antitumor effect of neurotensin receptor-targeted oncolytic adenovirus co-expressing decorin and Wnt antagonist in an orthotopic pancreatic tumor model.

Na Y, Choi JW, Kasala D, Hong J, Oh E, Li Y, Jung SJ, Kim SW, Yun CO.

J Control Release. 2015 Dec 28;220(Pt B):766-82. doi: 10.1016/j.jconrel.2015.10.015. Epub 2015 Oct 22.

PMID:
26471393
13.
14.

Chemo-radio-gene therapy for colorectal cancer cells using Escherichia coli uracil phosphoribosyltransferase gene.

Koyama F, Fujii H, Mukogawa T, Ueno M, Hamada H, Ishikawa H, Doi S, Nakao T, Matsumoto H, Shimatani H, Takeuchi T, Nakajima Y.

Anticancer Res. 2003 Mar-Apr;23(2B):1343-8.

PMID:
12820392
15.

Use of the Syrian hamster as an animal model for oncolytic adenovirus vectors.

Thomas MA, Spencer JF, Wold WS.

Methods Mol Med. 2007;130:169-83.

PMID:
17401172
16.
18.

Gene therapy for pancreatic cancer targeting the genomic alterations of tumor suppressor genes using replication-selective oncolytic adenovirus.

Sunamura M, Oonuma M, Motoi F, Abe H, Saitoh Y, Hoshida T, Ottomo S, Horii A, Matsuno S.

Hum Cell. 2002 Sep;15(3):138-50. Review.

PMID:
12703544
19.

Adenovirus-mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil.

Kanai F, Kawakami T, Hamada H, Sadata A, Yoshida Y, Tanaka T, Ohashi M, Tateishi K, Shiratori Y, Omata M.

Cancer Res. 1998 May 1;58(9):1946-51.

20.

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