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Methyl Antcinate A suppresses the population of cancer stem-like cells in MCF7 human breast cancer cell line.

Peng CY, Fong PC, Yu CC, Tsai WC, Tzeng YM, Chang WW.

Molecules. 2013 Feb 26;18(3):2539-48. doi: 10.3390/molecules18032539.


Neuropilin-1 is expressed by breast cancer stem-like cells and is linked to NF-κB activation and tumor sphere formation.

Glinka Y, Mohammed N, Subramaniam V, Jothy S, Prud'homme GJ.

Biochem Biophys Res Commun. 2012 Sep 7;425(4):775-80. doi: 10.1016/j.bbrc.2012.07.151. Epub 2012 Aug 2.


Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway.

Hsieh YC, Rao YK, Wu CC, Huang CY, Geethangili M, Hsu SL, Tzeng YM.

Chem Res Toxicol. 2010 Jul 19;23(7):1256-67. doi: 10.1021/tx100116a.


Inhibition of heat shock protein (Hsp) 27 potentiates the suppressive effect of Hsp90 inhibitors in targeting breast cancer stem-like cells.

Lee CH, Hong HM, Chang YY, Chang WW.

Biochimie. 2012 Jun;94(6):1382-9. doi: 10.1016/j.biochi.2012.02.034. Epub 2012 Mar 15.


Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines.

Cao L, Zhou Y, Zhai B, Liao J, Xu W, Zhang R, Li J, Zhang Y, Chen L, Qian H, Wu M, Yin Z.

BMC Gastroenterol. 2011 Jun 14;11:71. doi: 10.1186/1471-230X-11-71.


Ovatodiolide Inhibits Breast Cancer Stem/Progenitor Cells through SMURF2-Mediated Downregulation of Hsp27.

Lu KT, Wang BY, Chi WY, Chang-Chien J, Yang JJ, Lee HT, Tzeng YM, Chang WW.

Toxins (Basel). 2016 Apr 28;8(5). pii: E127. doi: 10.3390/toxins8050127.


Reduction of the putative CD44+CD24- breast cancer stem cell population by targeting the polyamine metabolic pathway with PG11047.

Cirenajwis H, Smiljanic S, Honeth G, Hegardt C, Marton LJ, Oredsson SM.

Anticancer Drugs. 2010 Nov;21(10):897-906. doi: 10.1097/CAD.0b013e32833f2f77.


Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner.

Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J.

BMC Cancer. 2015 May 13;15:401. doi: 10.1186/s12885-015-1394-7.


Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells.

Qiu M, Peng Q, Jiang I, Carroll C, Han G, Rymer I, Lippincott J, Zachwieja J, Gajiwala K, Kraynov E, Thibault S, Stone D, Gao Y, Sofia S, Gallo J, Li G, Yang J, Li K, Wei P.

Cancer Lett. 2013 Jan 28;328(2):261-70. doi: 10.1016/j.canlet.2012.09.023. Epub 2012 Oct 3.


Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs.

Guttilla IK, Phoenix KN, Hong X, Tirnauer JS, Claffey KP, White BA.

Breast Cancer Res Treat. 2012 Feb;132(1):75-85. doi: 10.1007/s10549-011-1534-y. Epub 2011 May 7.


Tumor selective cytotoxic action of a thiomorpholin hydroxamate inhibitor (TMI-1) in breast cancer.

Mezil L, Berruyer-Pouyet C, Cabaud O, Josselin E, Combes S, Brunel JM, Viens P, Collette Y, Birnbaum D, Lopez M.

PLoS One. 2012;7(9):e43409. doi: 10.1371/journal.pone.0043409. Epub 2012 Sep 18.


Anticancer effects of eleven triterpenoids derived from Antrodia camphorata.

Lee YP, Tsai WC, Ko CJ, Rao YK, Yang CR, Chen DR, Yang MH, Yang CC, Tzeng YM.

Anticancer Res. 2012 Jul;32(7):2727-34.


Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.

Grudzien P, Lo S, Albain KS, Robinson P, Rajan P, Strack PR, Golde TE, Miele L, Foreman KE.

Anticancer Res. 2010 Oct;30(10):3853-67.


Frondoside A has an anti-invasive effect by inhibiting TPA-induced MMP-9 activation via NF-κB and AP-1 signaling in human breast cancer cells.

Park SY, Kim YH, Kim Y, Lee SJ.

Int J Oncol. 2012 Sep;41(3):933-40. doi: 10.3892/ijo.2012.1518. Epub 2012 Jun 14.


Strigolactones: a novel class of phytohormones that inhibit the growth and survival of breast cancer cells and breast cancer stem-like enriched mammosphere cells.

Pollock CB, Koltai H, Kapulnik Y, Prandi C, Yarden RI.

Breast Cancer Res Treat. 2012 Aug;134(3):1041-55. doi: 10.1007/s10549-012-1992-x. Epub 2012 Mar 29.


NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells.

Zhou J, Zhang H, Gu P, Bai J, Margolick JB, Zhang Y.

Breast Cancer Res Treat. 2008 Oct;111(3):419-27. Epub 2007 Oct 27.


Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme.

Broadley KW, Hunn MK, Farrand KJ, Price KM, Grasso C, Miller RJ, Hermans IF, McConnell MJ.

Stem Cells. 2011 Mar;29(3):452-61. doi: 10.1002/stem.582.


Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment.

Rausch V, Liu L, Apel A, Rettig T, Gladkich J, Labsch S, Kallifatidis G, Kaczorowski A, Groth A, Gross W, Gebhard MM, Schemmer P, Werner J, Salnikov AV, Zentgraf H, Büchler MW, Herr I.

J Pathol. 2012 Jul;227(3):325-35. doi: 10.1002/path.3994. Epub 2012 Apr 18.


MiR-21 regulates epithelial-mesenchymal transition phenotype and hypoxia-inducible factor-1α expression in third-sphere forming breast cancer stem cell-like cells.

Han M, Wang Y, Liu M, Bi X, Bao J, Zeng N, Zhu Z, Mo Z, Wu C, Chen X.

Cancer Sci. 2012 Jun;103(6):1058-64. doi: 10.1111/j.1349-7006.2012.02281.x. Epub 2012 Apr 23.

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