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Items: 1 to 20 of 142

1.

A facile synthesis of deaza-analogues of the bisindole marine alkaloid topsentin.

Carbone A, Spanò V, Parrino B, Ciancimino C, Attanasi OA, Favi G.

Molecules. 2013 Feb 26;18(3):2518-27. doi: 10.3390/molecules18032518.

2.

3,5-bis(3'-indolyl)pyrazoles, analogues of marine alkaloid nortopsentin: synthesis and antitumor properties.

Diana P, Carbone A, Barraja P, Martorana A, Gia O, DallaVia L, Cirrincione G.

Bioorg Med Chem Lett. 2007 Nov 15;17(22):6134-7. Epub 2007 Sep 14.

PMID:
17911018
3.

Bisindole alkaloids of the topsentin and hamacanthin classes from a marine sponge Spongosorites sp.

Bao B, Sun Q, Yao X, Hong J, Lee CO, Cho HY, Jung JH.

J Nat Prod. 2007 Jan;70(1):2-8.

PMID:
17253840
4.

Synthesis and antiproliferative activity of [1,2,3,5]tetrazino[5,4-a]indoles, a new class of azolo-tetrazinones.

Barraja P, Diana P, Lauria A, Montalbano A, Almerico AM, Dattolo G, Cirrincione G.

Bioorg Med Chem. 2005 Jan 17;13(2):295-300.

PMID:
15598552
5.

Antimicrobial activity and cytotoxicity of bis(indole) alkaloids from the sponge Spongosorites sp.

Oh KB, Mar W, Kim S, Kim JY, Lee TH, Kim JG, Shin D, Sim CJ, Shin J.

Biol Pharm Bull. 2006 Mar;29(3):570-3.

6.

Synthesis and in vitro antiproliferative activity of amido and amino analogues of the marine alkaloid isogranulatimide.

Lavrard H, Salvetti B, Mathieu V, Rodriguez F, Kiss R, Delfourne E.

ChemMedChem. 2015 Apr;10(4):607-9. doi: 10.1002/cmdc.201500025. Epub 2015 Mar 3.

PMID:
25735892
8.

Synthesis and antitumor properties of 2,5-bis(3'-indolyl)thiophenes: analogues of marine alkaloid nortopsentin.

Diana P, Carbone A, Barraja P, Montalbano A, Martorana A, Dattolo G, Gia O, Dalla Via L, Cirrincione G.

Bioorg Med Chem Lett. 2007 Apr 15;17(8):2342-6. Epub 2007 Jan 26.

PMID:
17306531
9.

Total synthesis of marine sponge bis(indole) alkaloids of the topsentin class.

Guinchard X, Vallée Y, Denis JN.

J Org Chem. 2007 May 11;72(10):3972-5. Epub 2007 Apr 20.

PMID:
17444688
10.

Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.

Berry JM, Bradshaw TD, Fichtner I, Ren R, Schwalbe CH, Wells G, Chew EH, Stevens MF, Westwell AD.

J Med Chem. 2005 Jan 27;48(2):639-44.

PMID:
15658878
11.

Novel synthetic bis-indolic derivatives with antistaphylococcal activity, including against MRSA and VISA strains.

Caspar Y, Jeanty M, Blu J, Burchak O, Le Pihive E, Maigre L, Schneider D, Jolivalt C, Paris JM, Hequet A, Minassian F, Denis JN, Maurin M.

J Antimicrob Chemother. 2015;70(6):1727-37. doi: 10.1093/jac/dkv015. Epub 2015 Feb 16.

PMID:
25691323
12.

Cytotoxic bisindole alkaloids from a marine sponge Spongosorites sp.

Bao B, Sun Q, Yao X, Hong J, Lee CO, Sim CJ, Im KS, Jung JH.

J Nat Prod. 2005 May;68(5):711-5.

PMID:
15921415
13.

Marine Bacteria, XLVII - Psychrotolerant Bacteria from Extreme Antarctic Habitats as Producers of Rare Bis- and Trisindole Alkaloids.

Nair V, Schuhmann I, Anke H, Kelter G, Fiebig HH, Helmke E, Laatsch H.

Planta Med. 2016 Jun;82(9-10):910-8. doi: 10.1055/s-0042-108204. Epub 2016 Jun 10.

PMID:
27286331
14.

Synthesis and antiproliferative activity of 2,5-bis(3'-indolyl)pyrroles, analogues of the marine alkaloid nortopsentin.

Carbone A, Parrino B, Barraja P, Spanò V, Cirrincione G, Diana P, Maier A, Kelter G, Fiebig HH.

Mar Drugs. 2013 Mar 1;11(3):643-54. doi: 10.3390/md11030643.

15.

2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazoles: search for anticancer agents.

Noolvi MN, Patel HM, Kamboj S, Kaur A, Mann V.

Eur J Med Chem. 2012 Oct;56:56-69. doi: 10.1016/j.ejmech.2012.08.012. Epub 2012 Aug 16.

PMID:
22960694
16.

Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure-activity relationships of neocryptolepines and 6-methyl congeners.

Wang L, Switalska M, Mei ZW, Lu WJ, Takahara Y, Feng XW, El-Sayed Iel-T, Wietrzyk J, Inokuchi T.

Bioorg Med Chem. 2012 Aug 1;20(15):4820-9. doi: 10.1016/j.bmc.2012.05.054. Epub 2012 Jun 12.

PMID:
22748378
17.

Synthesis and anticancer activity of 2,4-disubstituted furo[3,2-b]indole derivatives.

Zhuang SH, Lin YC, Chou LC, Hsu MH, Lin HY, Huang CH, Lien JC, Kuo SC, Huang LJ.

Eur J Med Chem. 2013 Aug;66:466-79. doi: 10.1016/j.ejmech.2013.06.012. Epub 2013 Jun 18.

PMID:
23831809
18.

New bisindole alkaloids of the topsentin and hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei.

Casapullo A, Bifulco G, Bruno I, Riccio R.

J Nat Prod. 2000 Apr;63(4):447-51.

PMID:
10785411
19.

Synthesis and antitumor activity of 3-(2-phenyl-1,3-thiazol-4-yl)-1H-indoles and 3-(2-phenyl-1,3-thiazol-4-yl)-1H-7-azaindoles.

Diana P, Carbone A, Barraja P, Montalbano A, Parrino B, Lopergolo A, Pennati M, Zaffaroni N, Cirrincione G.

ChemMedChem. 2011 Jul 4;6(7):1300-9. doi: 10.1002/cmdc.201100078. Epub 2011 Apr 26.

PMID:
21523912
20.

Microwave assisted synthesis and in vitro cytotoxicities of substituted (Z)-2-amino-5-(1-benzyl-1H-indol-3-yl)methylene-1-methyl-1H-imidazol-4(5H)-ones against human tumor cell lines.

Penthala NR, Yerramreddy TR, Crooks PA.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):591-3. doi: 10.1016/j.bmcl.2009.11.083. Epub 2009 Nov 22.

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