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Items: 1 to 20 of 139

2.

GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.

White DT, McShea KM, Attar MA, Santy LC.

Mol Biol Cell. 2010 Feb 15;21(4):562-71. doi: 10.1091/mbc.E09-03-0217. Epub 2009 Dec 16.

3.

The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1.

Santy LC, Ravichandran KS, Casanova JE.

Curr Biol. 2005 Oct 11;15(19):1749-54.

4.

ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation.

Koubek EJ, Santy LC.

Small GTPases. 2016 Aug 12:1-18. doi: 10.1080/21541248.2016.1219186. [Epub ahead of print]

PMID:
27562622
5.

CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration.

Attar MA, Salem JC, Pursel HS, Santy LC.

Exp Cell Res. 2012 Feb 1;318(3):228-37. doi: 10.1016/j.yexcr.2011.10.018. Epub 2011 Nov 7.

PMID:
22085542
6.

ARL4D recruits cytohesin-2/ARNO to modulate actin remodeling.

Li CC, Chiang TC, Wu TS, Pacheco-Rodriguez G, Moss J, Lee FJ.

Mol Biol Cell. 2007 Nov;18(11):4420-37. Epub 2007 Sep 5.

7.
8.

The ADP-ribosylation factor (ARF)-related GTPase ARF-related protein binds to the ARF-specific guanine nucleotide exchange factor cytohesin and inhibits the ARF-dependent activation of phospholipase D.

Schürmann A, Schmidt M, Asmus M, Bayer S, Fliegert F, Koling S, Massmann S, Schilf C, Subauste MC, Voss M, Jakobs KH, Joost HG.

J Biol Chem. 1999 Apr 2;274(14):9744-51.

9.

RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo.

Katoh H, Negishi M.

Nature. 2003 Jul 24;424(6947):461-4.

PMID:
12879077
10.

Dock180-ELMO cooperation in Rac activation.

Lu M, Ravichandran KS.

Methods Enzymol. 2006;406:388-402.

PMID:
16472672
11.
12.

The N-terminal coiled-coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with Galphaq.

Laroche G, Giguère PM, Dupré E, Dupuis G, Parent JL.

Mol Cell Biochem. 2007 Dec;306(1-2):141-52. Epub 2007 Sep 6.

PMID:
17846866
13.

C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF.

Akakura S, Kar B, Singh S, Cho L, Tibrewal N, Sanokawa-Akakura R, Reichman C, Ravichandran KS, Birge RB.

J Cell Physiol. 2005 Jul;204(1):344-51.

PMID:
15700267
14.
15.

The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.

Patel M, Chiang TC, Tran V, Lee FJ, Côté JF.

J Biol Chem. 2011 Nov 11;286(45):38969-79. doi: 10.1074/jbc.M111.274191. Epub 2011 Sep 19.

16.

Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells.

Vallés AM, Beuvin M, Boyer B.

J Biol Chem. 2004 Oct 22;279(43):44490-6. Epub 2004 Aug 12.

17.

The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration.

Lee S, Wurtzel JG, Goldfinger LE.

Biochem Biophys Res Commun. 2014 Nov 28;454(4):560-5. doi: 10.1016/j.bbrc.2014.10.114. Epub 2014 Oct 30.

18.

Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activity.

Venkateswarlu K.

J Biol Chem. 2003 Oct 31;278(44):43460-9. Epub 2003 Aug 14.

19.

An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells.

Nishiya N, Kiosses WB, Han J, Ginsberg MH.

Nat Cell Biol. 2005 Apr;7(4):343-52. Epub 2005 Mar 27. Erratum in: Nat Cell Biol. 2005 May;7(5):531.

PMID:
15793570
20.

Cytohesin-2/ARNO, through its interaction with focal adhesion adaptor protein paxillin, regulates preadipocyte migration via the downstream activation of Arf6.

Torii T, Miyamoto Y, Sanbe A, Nishimura K, Yamauchi J, Tanoue A.

J Biol Chem. 2010 Jul 30;285(31):24270-81. doi: 10.1074/jbc.M110.125658. Epub 2010 Jun 4.

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