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Items: 1 to 20 of 97

1.

A potent antioxidant small molecule aimed at targeting metal-based oxidative stress in neurodegenerative disorders.

Lincoln KM, Gonzalez P, Richardson TE, Julovich DA, Saunders R, Simpkins JW, Green KN.

Chem Commun (Camb). 2013 Apr 4;49(26):2712-4. doi: 10.1039/c2cc36808k.

2.

How can we target oxidative stress in the treatment of neurodegenerative diseases?

Akasaka H, Ruan KH.

Future Med Chem. 2016 May;8(8):835-9. doi: 10.4155/fmc-2016-0065. Epub 2016 May 13. No abstract available.

PMID:
27173453
4.

Design, synthesis, stereochemistry and antioxidant properties of various 7-alkylated 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones.

Park DH, Venkatesan J, Kim SK, Parthiban P.

Bioorg Med Chem Lett. 2012 Sep 15;22(18):6004-9. doi: 10.1016/j.bmcl.2012.06.071. Epub 2012 Jun 30.

PMID:
22884407
5.

Transition metal complexes with N, S donor ligands as synthetic antioxidants: synthesis, characterization and antioxidant activity.

Choudhary A, Sharma R, Nagar M, Mohsin M.

J Enzyme Inhib Med Chem. 2011 Jun;26(3):394-403. doi: 10.3109/14756366.2010.518966. Epub 2010 Oct 13.

PMID:
20939764
6.

Low molecular weight compounds with transition metals as free radical scavengers and novel therapeutic agents.

Bencini A, Failli P, Valtancoli B, Bani D.

Cardiovasc Hematol Agents Med Chem. 2010 Jul;8(3):128-46. Review.

PMID:
20438441
7.

Synthesis and antioxidant potential of novel synthetic benzophenone analogues.

Tzanova T, Gerova M, Petrov O, Karaivanova M, Bagrel D.

Eur J Med Chem. 2009 Jun;44(6):2724-30. doi: 10.1016/j.ejmech.2008.09.010. Epub 2008 Sep 19.

PMID:
18950902
8.

Transition metal complexes of 2, 6-di ((phenazonyl-4-imino) methyl)-4-methylphenol: structure and biological evaluation.

Liu H, Shi X, Xu M, Li Z, Huang L, Bai D, Zeng Z.

Eur J Med Chem. 2011 May;46(5):1638-47. doi: 10.1016/j.ejmech.2011.02.012. Epub 2011 Feb 15.

PMID:
21371788
9.

Multitarget trehalose-carnosine conjugates inhibit Aβ aggregation, tune copper(II) activity and decrease acrolein toxicity.

Grasso GI, Bellia F, Arena G, Satriano C, Vecchio G, Rizzarelli E.

Eur J Med Chem. 2017 Jul 28;135:447-457. doi: 10.1016/j.ejmech.2017.04.060. Epub 2017 Apr 24.

PMID:
28475972
10.

Synthesis and evaluation of antioxidant activity of new quinoline-2-carbaldehyde hydrazone derivatives: bioisosteric melatonin analogues.

Puskullu MO, Shirinzadeh H, Nenni M, Gurer-Orhan H, Suzen S.

J Enzyme Inhib Med Chem. 2016;31(1):121-5. doi: 10.3109/14756366.2015.1005012. Epub 2015 May 5.

PMID:
25942363
11.

Synthesis, physicochemical properties and antioxidant activity of deferiprone-cyclodextrin conjugates and their iron(III) complexes.

Puglisi A, Spencer J, Oliveri V, Vecchio G, Kong X, Clarke J, Milton J.

Dalton Trans. 2012 Mar 14;41(10):2877-83. doi: 10.1039/c1dt11677k. Epub 2011 Nov 30.

PMID:
22130677
12.

A novel dicyclodextrinyl ditelluride compound with antioxidant activity.

Ren X, Xue Y, Zhang K, Liu J, Luo G, Zheng J, Mu Y, Shen J.

FEBS Lett. 2001 Nov 2;507(3):377-80.

13.

New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection.

Buendia I, Navarro E, Michalska P, Gameiro I, Egea J, Abril S, López A, González-Lafuente L, López MG, León R.

Future Med Chem. 2015;7(15):1961-9. doi: 10.4155/fmc.15.99. Epub 2015 Oct 23.

PMID:
26496465
14.

Potential antitumour and pro-oxidative effects of (E)-methyl 2-(7-chloroquinolin-4-ylthio)-3-(4-hydroxyphenyl) acrylate (QNACR).

Rodrigues JR, Ferrer R, Gamboa N, Charris J, Antunes F.

J Enzyme Inhib Med Chem. 2013 Dec;28(6):1300-6. doi: 10.3109/14756366.2012.736385. Epub 2012 Nov 9.

PMID:
23137315
15.

Dibenzo[1,4,5]thiadiazepine: a hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases.

González-Muñoz GC, Arce MP, Pérez C, Romero A, Villarroya M, López MG, Conde S, Rodríguez-Franco MI.

Eur J Med Chem. 2014 Jun 23;81:350-8. doi: 10.1016/j.ejmech.2014.04.075. Epub 2014 May 12.

PMID:
24858540
16.

Antioxidant action of 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity.

Han X, Zhu S, Wang B, Chen L, Li R, Yao W, Qu Z.

Neurochem Int. 2014 Jan;64:18-23. doi: 10.1016/j.neuint.2013.10.018. Epub 2013 Nov 9.

PMID:
24220540
17.
18.

New concepts to fight oxidative stress: nanosized three-dimensional supramolecular antioxidant assemblies.

Richard PU, Duskey JT, Stolarov S, Spulber M, Palivan CG.

Expert Opin Drug Deliv. 2015;12(9):1527-45. doi: 10.1517/17425247.2015.1036738. Epub 2015 Apr 16. Review.

PMID:
25882382
19.

Redox catalysts as sensitisers towards oxidative stress.

Giles NM, Gutowski NJ, Giles GI, Jacob C.

FEBS Lett. 2003 Jan 30;535(1-3):179-82.

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