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Items: 1 to 20 of 168

1.

ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement.

Choi HJ, Sanders TA, Tormos KV, Ameri K, Tsai JD, Park AM, Gonzalez J, Rajah AM, Liu X, Quinonez DM, Rinaudo PF, Maltepe E.

PLoS One. 2013;8(2):e56949. doi: 10.1371/journal.pone.0056949. Epub 2013 Feb 21.

2.

LIMK1 regulates human trophoblast invasion/differentiation and is down-regulated in preeclampsia.

Zhou Y, Yuge A, Rajah AM, Unek G, Rinaudo PF, Maltepe E.

Am J Pathol. 2014 Dec;184(12):3321-31. doi: 10.1016/j.ajpath.2014.08.013. Epub 2014 Oct 13.

3.

Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation.

Cowden Dahl KD, Fryer BH, Mack FA, Compernolle V, Maltepe E, Adelman DM, Carmeliet P, Simon MC.

Mol Cell Biol. 2005 Dec;25(23):10479-91.

4.

Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor-Dependent Manner.

Wakeland AK, Soncin F, Moretto-Zita M, Chang CW, Horii M, Pizzo D, Nelson KK, Laurent LC, Parast MM.

Am J Pathol. 2017 Apr;187(4):767-780. doi: 10.1016/j.ajpath.2016.11.018. Epub 2017 Feb 4.

5.

Hypoxia induced HIF-1/HIF-2 activity alters trophoblast transcriptional regulation and promotes invasion.

Highet AR, Khoda SM, Buckberry S, Leemaqz S, Bianco-Miotto T, Harrington E, Ricciardelli C, Roberts CT.

Eur J Cell Biol. 2015 Dec;94(12):589-602. doi: 10.1016/j.ejcb.2015.10.004. Epub 2015 Oct 24.

PMID:
26531845
6.

Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency.

Xie Y, Zhou S, Jiang Z, Dai J, Puscheck EE, Lee I, Parker G, Hüttemann M, Rappolee DA.

Stem Cell Res. 2014 Nov;13(3 Pt A):478-91. doi: 10.1016/j.scr.2014.07.007. Epub 2014 Jul 30.

7.

Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses.

Adelman DM, Gertsenstein M, Nagy A, Simon MC, Maltepe E.

Genes Dev. 2000 Dec 15;14(24):3191-203.

8.

Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta.

Maltepe E, Krampitz GW, Okazaki KM, Red-Horse K, Mak W, Simon MC, Fisher SJ.

Development. 2005 Aug;132(15):3393-403. Epub 2005 Jun 29.

9.

The maternally expressed gene Tssc3 regulates the expression of MASH2 transcription factor in mouse trophoblast stem cells through the AKT-Sp1 signaling pathway.

Takao T, Asanoma K, Tsunematsu R, Kato K, Wake N.

J Biol Chem. 2012 Dec 14;287(51):42685-94. doi: 10.1074/jbc.M112.388777. Epub 2012 Oct 15.

10.

Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsia.

Caniggia I, Winter J, Lye SJ, Post M.

Placenta. 2000 Mar-Apr;21 Suppl A:S25-30.

PMID:
10831118
11.

Essential role of the ERK/MAPK pathway in blood-placental barrier formation.

Nadeau V, Charron J.

Development. 2014 Jul;141(14):2825-37. doi: 10.1242/dev.107409. Epub 2014 Jun 19.

12.

Adrenomedullin promotes rat trophoblast stem cell differentiation.

Gao H, Liebenthal DA, Yallampalli U, Yallampalli C.

Biol Reprod. 2014 Sep;91(3):65. doi: 10.1095/biolreprod.114.120378. Epub 2014 Jul 24.

14.

Hypoxia represses the differentiation of Rcho-1 rat trophoblast giant cells.

Takeda T, Sakata M, Isobe A, Yamamoto T, Nishimoto F, Minekawa R, Okamoto Y, Tasaka K, Murata Y.

Gynecol Obstet Invest. 2007;63(4):188-94. Epub 2006 Nov 30.

PMID:
17139180
15.

Hypoxia and trophoblast differentiation: a key role for PPARγ.

Tache V, Ciric A, Moretto-Zita M, Li Y, Peng J, Maltepe E, Milstone DS, Parast MM.

Stem Cells Dev. 2013 Nov 1;22(21):2815-24. doi: 10.1089/scd.2012.0596. Epub 2013 Jul 12.

16.

Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.

Li S, Moore AK, Zhu J, Li X, Zhou H, Lin J, He Y, Xing F, Pan Y, Bohler HC, Ding J, Cooney AJ, Lan Z, Lei Z.

Biol Reprod. 2016 Feb;94(2):41. doi: 10.1095/biolreprod.115.136358. Epub 2016 Jan 13.

18.

Gene Expression Profiling Reveals a Novel Regulatory Role for Sox21 Protein in Mouse Trophoblast Stem Cell Differentiation.

Moretto Zita M, Soncin F, Natale D, Pizzo D, Parast M.

J Biol Chem. 2015 Dec 11;290(50):30152-62. doi: 10.1074/jbc.M115.659094. Epub 2015 Oct 21.

19.

HIF-2α/ARNT complex regulates hair development via induction of p21(Waf1/Cip1) and p27(Kip1).

Imamura Y, Tomita S, Imanishi M, Kihira Y, Ikeda Y, Ishizawa K, Tsuchiya K, Tamaki T.

FASEB J. 2014 Jun;28(6):2517-24. doi: 10.1096/fj.13-244079. Epub 2014 Mar 5.

PMID:
24599965
20.

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

Covello KL, Kehler J, Yu H, Gordan JD, Arsham AM, Hu CJ, Labosky PA, Simon MC, Keith B.

Genes Dev. 2006 Mar 1;20(5):557-70.

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