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Items: 1 to 20 of 101

1.

Role of the Toll Like receptor (TLR) radical cycle in chronic inflammation: possible treatments targeting the TLR4 pathway.

Lucas K, Maes M.

Mol Neurobiol. 2013 Aug;48(1):190-204. doi: 10.1007/s12035-013-8425-7. Epub 2013 Feb 26. Review.

PMID:
23436141
2.

The Toll-Like Receptor Radical Cycle Pathway: A New Drug Target in Immune-Related Chronic Fatigue.

Lucas K, Morris G, Anderson G, Maes M.

CNS Neurol Disord Drug Targets. 2015;14(7):838-54. Review.

PMID:
25801843
3.

The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.

Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc A, Kodys K, Kurt-Jones E, Szabo G.

Hepatology. 2008 Oct;48(4):1224-31. doi: 10.1002/hep.22470.

PMID:
18792393
4.

Activation of Toll-like receptors by Burkholderia pseudomallei.

West TE, Ernst RK, Jansson-Hutson MJ, Skerrett SJ.

BMC Immunol. 2008 Aug 8;9:46. doi: 10.1186/1471-2172-9-46.

5.

Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation.

Li J, Csakai A, Jin J, Zhang F, Yin H.

ChemMedChem. 2016 Jan 19;11(2):154-65. doi: 10.1002/cmdc.201500188. Epub 2015 Jul 1. Review.

6.

Inducible Toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue.

Vitseva OI, Tanriverdi K, Tchkonia TT, Kirkland JL, McDonnell ME, Apovian CM, Freedman J, Gokce N.

Obesity (Silver Spring). 2008 May;16(5):932-7. doi: 10.1038/oby.2008.25. Epub 2008 Feb 21.

7.
8.

Suppression of Toll-like receptor 4 activation by caffeic acid phenethyl ester is mediated by interference of LPS binding to MD2.

Kim SY, Koo JE, Seo YJ, Tyagi N, Jeong E, Choi J, Lim KM, Park ZY, Lee JY.

Br J Pharmacol. 2013 Apr;168(8):1933-45. doi: 10.1111/bph.12091.

9.

Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule.

Lysakova-Devine T, Keogh B, Harrington B, Nagpal K, Halle A, Golenbock DT, Monie T, Bowie AG.

J Immunol. 2010 Oct 1;185(7):4261-71. doi: 10.4049/jimmunol.1002013. Epub 2010 Aug 27.

10.

The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation.

Molteni M, Gemma S, Rossetti C.

Mediators Inflamm. 2016;2016:6978936. doi: 10.1155/2016/6978936. Epub 2016 May 18. Review.

11.

Toll-like receptors 2 and 4 mediate hyperglycemia induced macrovascular aortic endothelial cell inflammation and perturbation of the endothelial glycocalyx.

Pahwa R, Nallasamy P, Jialal I.

J Diabetes Complications. 2016 May-Jun;30(4):563-72. doi: 10.1016/j.jdiacomp.2016.01.014. Epub 2016 Jan 22.

PMID:
26908090
12.

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.

Rallabhandi P, Phillips RL, Boukhvalova MS, Pletneva LM, Shirey KA, Gioannini TL, Weiss JP, Chow JC, Hawkins LD, Vogel SN, Blanco JC.

MBio. 2012 Aug 7;3(4). pii: e00218-12. doi: 10.1128/mBio.00218-12. Print 2012.

13.

Saturated fatty acids trigger TLR4-mediated inflammatory response.

Rocha DM, Caldas AP, Oliveira LL, Bressan J, Hermsdorff HH.

Atherosclerosis. 2016 Jan;244:211-5. doi: 10.1016/j.atherosclerosis.2015.11.015. Epub 2015 Dec 2. Review.

PMID:
26687466
14.

The TRIPS (Toll-like receptors in immuno-inflammatory pathogenesis) Hypothesis: a novel postulate to understand schizophrenia.

Venkatasubramanian G, Debnath M.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 1;44:301-11. doi: 10.1016/j.pnpbp.2013.04.001. Epub 2013 Apr 12.

PMID:
23587629
15.
16.

Decoding cell death signals in liver inflammation.

Brenner C, Galluzzi L, Kepp O, Kroemer G.

J Hepatol. 2013 Sep;59(3):583-94. doi: 10.1016/j.jhep.2013.03.033. Epub 2013 Apr 6. Review.

17.
18.

Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells.

Xia MZ, Liang YL, Wang H, Chen X, Huang YY, Zhang ZH, Chen YH, Zhang C, Zhao M, Xu DX, Song LH.

J Pineal Res. 2012 Nov;53(4):325-34. doi: 10.1111/j.1600-079X.2012.01002.x. Epub 2012 Apr 27.

PMID:
22537289
19.

Loss of Toll-like receptor 2 and 4 leads to differential induction of endoplasmic reticulum stress and proapoptotic responses in the intestinal epithelium under conditions of chronic inflammation.

Messlik A, Schmechel S, Kisling S, Bereswill S, Heimesaat MM, Fischer A, Göbel U, Haller D.

J Proteome Res. 2009 Oct;8(10):4406-17. doi: 10.1021/pr9000465.

PMID:
19681597
20.

Innate immune receptor Toll-like receptor 4 signalling in neuropsychiatric diseases.

García Bueno B, Caso JR, Madrigal JL, Leza JC.

Neurosci Biobehav Rev. 2016 May;64:134-47. doi: 10.1016/j.neubiorev.2016.02.013. Epub 2016 Feb 19. Review.

PMID:
26905767

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