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Items: 1 to 20 of 95

1.

Using fluorescent post-labeling to probe the subcellular localization of DNA-targeted platinum anticancer agents.

Ding S, Qiao X, Suryadi J, Marrs GS, Kucera GL, Bierbach U.

Angew Chem Int Ed Engl. 2013 Mar 18;52(12):3350-4. doi: 10.1002/anie.201210079. Epub 2013 Feb 20. No abstract available.

2.

Investigating the cellular fate of a DNA-targeted platinum-based anticancer agent by orthogonal double-click chemistry.

Qiao X, Ding S, Liu F, Kucera GL, Bierbach U.

J Biol Inorg Chem. 2014 Mar;19(3):415-26. doi: 10.1007/s00775-013-1086-1. Epub 2014 Jan 10.

3.

Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents.

Ding S, Qiao X, Kucera GL, Bierbach U.

J Med Chem. 2012 Nov 26;55(22):10198-203. doi: 10.1021/jm301278c. Epub 2012 Oct 25.

4.

Selective aggregation of a platinum-gadolinium complex within a tumor-cell nucleus.

Crossley EL, Aitken JB, Vogt S, Harris HH, Rendina LM.

Angew Chem Int Ed Engl. 2010 Feb 8;49(7):1231-3. doi: 10.1002/anie.200902309. No abstract available.

PMID:
20077549
5.

Cytotoxic activities, cellular uptake, gene regulation, and optical imaging of novel platinum(II) complexes.

Gao J, Liu YG, Zingaro RA.

Chem Res Toxicol. 2009 Oct;22(10):1705-12. doi: 10.1021/tx900180v.

PMID:
19694485
6.

A targeted theranostic platinum(IV) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation.

Yuan Y, Chen Y, Tang BZ, Liu B.

Chem Commun (Camb). 2014 Apr 14;50(29):3868-70. doi: 10.1039/c3cc49516g. Epub 2014 Mar 4.

PMID:
24589580
7.

Analysis of the DNA damage produced by a platinum-acridine antitumor agent and its effects in NCI-H460 lung cancer cells.

Qiao X, Zeitany AE, Wright MW, Essader AS, Levine KE, Kucera GL, Bierbach U.

Metallomics. 2012 Jul;4(7):645-52. doi: 10.1039/c2mt20031g. Epub 2012 Mar 29.

8.

Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines.

Ma Z, Saluta G, Kucera GL, Bierbach U.

Bioorg Med Chem Lett. 2008 Jul 1;18(13):3799-801. doi: 10.1016/j.bmcl.2008.05.043. Epub 2008 May 16.

9.

Isoquino[4,5-bc]acridines: design, synthesis and evaluation of DNA binding, anti-tumor and DNA photo-damaging ability.

Yang P, Yang Q, Qian X, Tong L, Li X.

J Photochem Photobiol B. 2006 Sep 1;84(3):221-6. Epub 2006 May 22.

PMID:
16714120
10.

Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer.

Ding S, Qiao X, Kucera GL, Bierbach U.

Chem Commun (Camb). 2013 Mar 25;49(24):2415-7. doi: 10.1039/c3cc38957j.

11.

A fluorescent probe for investigating the activation of anticancer platinum(IV) prodrugs based on the cisplatin scaffold.

Montagner D, Yap SQ, Ang WH.

Angew Chem Int Ed Engl. 2013 Nov 4;52(45):11785-9. doi: 10.1002/anie.201305734. Epub 2013 Sep 17. No abstract available.

PMID:
24105908
12.

Structural studies of interactions between anticancer platinum drugs and DNA.

Yang D, Wang AH.

Prog Biophys Mol Biol. 1996;66(1):81-111. Review. No abstract available.

PMID:
9107133
14.

Fluorescent platinum nanoclusters: synthesis, purification, characterization, and application to bioimaging.

Tanaka S, Miyazaki J, Tiwari DK, Jin T, Inouye Y.

Angew Chem Int Ed Engl. 2011 Jan 10;50(2):431-5. doi: 10.1002/anie.201004907. No abstract available.

PMID:
21154543
15.

Amphiphilic Cyanine-Platinum Conjugates as Fluorescent Nanodrugs.

Sun T, Li Z, Xie Z, Jing X.

Chem Asian J. 2016 Jan;11(2):221-5. doi: 10.1002/asia.201501163. Epub 2015 Dec 3.

PMID:
26556434
16.

PT-ACRAMTU, a platinum-acridine anticancer agent, lengthens and aggregates, but does not stiffen or soften DNA.

Dutta S, Snyder MJ, Rosile D, Binz KL, Roll EH, Suryadi J, Bierbach U, Guthold M.

Cell Biochem Biophys. 2013;67(3):1103-13. doi: 10.1007/s12013-013-9614-8.

17.

A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer.

Ma Z, Choudhury JR, Wright MW, Day CS, Saluta G, Kucera GL, Bierbach U.

J Med Chem. 2008 Dec 11;51(23):7574-80. doi: 10.1021/jm800900g.

18.

A new way to detect the interaction of DNA and anticancer drugs based on the decreased resonance light scattering signal and its potential application.

Chen Z, Song T, Peng Y, Chen X, Chen J, Zhang G, Qian S.

Analyst. 2011 Oct 7;136(19):3927-33. doi: 10.1039/c1an15507e. Epub 2011 Aug 19.

PMID:
21858274
19.

Convenient detection of metal-DNA, metal-RNA, and metal-protein adducts with a click-modified Pt(II) complex.

Moghaddam AD, White JD, Cunningham RM, Loes AN, Haley MM, DeRose VJ.

Dalton Trans. 2015 Feb 28;44(8):3536-9. doi: 10.1039/c4dt02649g.

PMID:
25338004
20.

Comparative chemogenomics to examine the mechanism of action of dna-targeted platinum-acridine anticancer agents.

Cheung-Ong K, Song KT, Ma Z, Shabtai D, Lee AY, Gallo D, Heisler LE, Brown GW, Bierbach U, Giaever G, Nislow C.

ACS Chem Biol. 2012 Nov 16;7(11):1892-901. doi: 10.1021/cb300320d. Epub 2012 Sep 5.

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