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Toll-like receptor 4 mutation protects obese mice against endothelial dysfunction by decreasing NADPH oxidase isoforms 1 and 4.

Liang CF, Liu JT, Wang Y, Xu A, Vanhoutte PM.

Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):777-84. doi: 10.1161/ATVBAHA.112.301087. Epub 2013 Feb 14.


Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress.

Zhang H, Zhang J, Ungvari Z, Zhang C.

Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1164-71. doi: 10.1161/ATVBAHA.109.187146. Epub 2009 May 28.


Endothelial nitric oxide synthase enhancer reduces oxidative stress and restores endothelial function in db/db mice.

Cheang WS, Wong WT, Tian XY, Yang Q, Lee HK, He GW, Yao X, Huang Y.

Cardiovasc Res. 2011 Nov 1;92(2):267-75. doi: 10.1093/cvr/cvr233. Epub 2011 Aug 29.


Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.

Bitar MS, Wahid S, Mustafa S, Al-Saleh E, Dhaunsi GS, Al-Mulla F.

Eur J Pharmacol. 2005 Mar 21;511(1):53-64.


Gene deletion of protein tyrosine phosphatase 1B protects against sepsis-induced cardiovascular dysfunction and mortality.

Coquerel D, Neviere R, Delile E, Mulder P, Marechal X, Montaigne D, Renet S, Remy-Jouet I, Gomez E, Henry JP, do Rego JC, Richard V, Tamion F.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):1032-44. doi: 10.1161/ATVBAHA.114.303450. Epub 2014 Feb 27.


Type 2 diabetes severely impairs structural and functional adaptation of rat resistance arteries to chronic changes in blood flow.

Belin de Chantemèle EJ, Vessières E, Guihot AL, Toutain B, Maquignau M, Loufrani L, Henrion D.

Cardiovasc Res. 2009 Mar 1;81(4):788-96. doi: 10.1093/cvr/cvn334. Epub 2008 Dec 2.


Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition.

Schlüter T, Steinbach AC, Steffen A, Rettig R, Grisk O.

Cardiovasc Res. 2008 Nov 1;80(2):271-9. doi: 10.1093/cvr/cvn185. Epub 2008 Jul 2.


The PPARgamma ligand, rosiglitazone, reduces vascular oxidative stress and NADPH oxidase expression in diabetic mice.

Hwang J, Kleinhenz DJ, Rupnow HL, Campbell AG, Thulé PM, Sutliff RL, Hart CM.

Vascul Pharmacol. 2007 Jun;46(6):456-62. Epub 2007 Feb 8.


Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice.

Chataigneau T, Félétou M, Huang PL, Fishman MC, Duhault J, Vanhoutte PM.

Br J Pharmacol. 1999 Jan;126(1):219-26.


Saxagliptin prevents vascular remodeling and oxidative stress in db/db mice. Role of endothelial nitric oxide synthase uncoupling and cyclooxygenase.

Solini A, Rossi C, Duranti E, Taddei S, Natali A, Virdis A.

Vascul Pharmacol. 2016 Jan;76:62-71. doi: 10.1016/j.vph.2015.10.002. Epub 2015 Oct 8.


IL-6 deficiency protects against angiotensin II induced endothelial dysfunction and hypertrophy.

Schrader LI, Kinzenbaw DA, Johnson AW, Faraci FM, Didion SP.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2576-81. Epub 2007 Oct 25.


Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice.

Ketonen J, Pilvi T, Mervaala E.

Heart Vessels. 2010 May;25(3):254-62. doi: 10.1007/s00380-009-1182-x. Epub 2010 May 29.


Involvement of cyclo-oxygenase-1-mediated prostacyclin synthesis in the vasoconstrictor activity evoked by ACh in mouse arteries.

Liu B, Luo W, Zhang Y, Li H, Zhu N, Huang D, Zhou Y.

Exp Physiol. 2012 Feb;97(2):277-89. doi: 10.1113/expphysiol.2011.062034. Epub 2011 Nov 11.


NADPH oxidase accounts for enhanced superoxide production and impaired endothelium-dependent smooth muscle relaxation in BKbeta1-/- mice.

Oelze M, Warnholtz A, Faulhaber J, Wenzel P, Kleschyov AL, Coldewey M, Hink U, Pongs O, Fleming I, Wassmann S, Meinertz T, Ehmke H, Daiber A, Münzel T.

Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1753-9. Epub 2006 Jun 8.


Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension.

Bagnost T, Ma L, da Silva RF, Rezakhaniha R, Houdayer C, Stergiopulos N, André C, Guillaume Y, Berthelot A, Demougeot C.

Cardiovasc Res. 2010 Aug 1;87(3):569-77. doi: 10.1093/cvr/cvq081. Epub 2010 Mar 10.


Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice.

Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo J, Cheang WS, Lau CW, Kwan KM, Wang N, Yao X, Huang Y.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):152-9. doi: 10.1161/ATVBAHA.113.302696. Epub 2013 Nov 7.


Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5' adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor δ pathway.

Cheang WS, Tian XY, Wong WT, Lau CW, Lee SS, Chen ZY, Yao X, Wang N, Huang Y.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):830-6. doi: 10.1161/ATVBAHA.113.301938. Epub 2014 Jan 30.


Lipocalin-2 deficiency prevents endothelial dysfunction associated with dietary obesity: role of cytochrome P450 2C inhibition.

Liu JT, Song E, Xu A, Berger T, Mak TW, Tse HF, Law IK, Huang B, Liang Y, Vanhoutte PM, Wang Y.

Br J Pharmacol. 2012 Jan;165(2):520-31. doi: 10.1111/j.1476-5381.2011.01587.x.


Exercise training improves endothelial function via adiponectin-dependent and independent pathways in type 2 diabetic mice.

Lee S, Park Y, Dellsperger KC, Zhang C.

Am J Physiol Heart Circ Physiol. 2011 Aug;301(2):H306-14. doi: 10.1152/ajpheart.01306.2010. Epub 2011 May 20.

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