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Items: 1 to 20 of 99

1.

Spiro heterocycles as potential inhibitors of SIRT1: Pd/C-mediated synthesis of novel N-indolylmethyl spiroindoline-3,2'-quinazolines.

Rambabu D, Raja G, Yogi Sreenivas B, Seerapu GP, Lalith Kumar K, Deora GS, Haldar D, Rao MV, Pal M.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1351-7. doi: 10.1016/j.bmcl.2012.12.089. Epub 2013 Jan 5.

PMID:
23410798
2.

Synthesis and evaluation as NOP ligands of some spiro[piperidine-4,2'(1'H)-quinazolin]-4'(3'H)-ones and spiro[piperidine-4,5'(6'H)-[1,2,4]triazolo[1,5-c]quinazolines].

Mustazza C, Borioni A, Sestili I, Sbraccia M, Rodomonte A, Ferretti R, Del Giudice MR.

Chem Pharm Bull (Tokyo). 2006 May;54(5):611-22.

3.

Sequential coupling/desilylation-coupling/cyclization in a single pot under Pd/C-Cu catalysis: synthesis of 2-(hetero)aryl indoles.

Rao RM, Reddy UC, Alinakhi, Mulakayala N, Alvala M, Arunasree MK, Poondra RR, Iqbal J, Pal M.

Org Biomol Chem. 2011 May 21;9(10):3808-16. doi: 10.1039/c0ob01161d. Epub 2011 Mar 29.

PMID:
21448470
4.

Biological activities and quantitative structure-activity relationships of spiro[imidazolidine-4,4'(1'H)-quinazoline]-2,2',5(3'H)-triones as aldose reductase inhibitors.

Yamagishi M, Yamada Y, Ozaki K, Asao M, Shimizu R, Suzuki M, Matsumoto M, Matsuoka Y, Matsumoto K.

J Med Chem. 1992 May 29;35(11):2085-94.

PMID:
1597858
5.

Palladium(II)-catalyzed synthesis of 2H,3'H-spiro[benzofuran-3,2'-naphthoquinones].

Claes P, Jacobs J, Kesteleyn B, Nguyen Van T, De Kimpe N.

J Org Chem. 2013 Sep 6;78(17):8330-9. doi: 10.1021/jo400852z. Epub 2013 Aug 14.

PMID:
23859820
6.

5'-Phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (aggrecanase-2).

Bursavich MG, Gilbert AM, Lombardi S, Georgiadis KE, Reifenberg E, Flannery CR, Morris EA.

Bioorg Med Chem Lett. 2007 Oct 15;17(20):5630-3. Epub 2007 Aug 19.

PMID:
17804234
7.

Total syntheses of (±)-spiroquinazoline, (-)-alantryphenone, (+)-lapatin A, and (-)-quinadoline B.

Wu M, Ma D.

Angew Chem Int Ed Engl. 2013 Sep 9;52(37):9759-62. doi: 10.1002/anie.201303893. Epub 2013 Jul 19. No abstract available.

PMID:
23868659
8.

Domino Pd-catalyzed Heck cyclization and bismuth-catalyzed hydroamination: formal synthesis of elacomine and isoelacomine.

Kamisaki H, Nanjo T, Tsukano C, Takemoto Y.

Chemistry. 2011 Jan 10;17(2):626-33. doi: 10.1002/chem.201002287. Epub 2010 Nov 16.

PMID:
21207582
9.

Synthesis of highly functionalised spiro-indoles by a halogen atom transfer radical cyclization.

Stevens CV, Van Meenen E, Eeckhout Y, Vanderhoydonck B, Hooghe W.

Chem Commun (Camb). 2005 Oct 14;(38):4827-9. Epub 2005 Sep 2.

PMID:
16193128
11.

Oxidative ring expansion of spirocyclic oxindole derivatives.

Bergman J, Arewång CJ, Svensson PH.

J Org Chem. 2014 Oct 3;79(19):9065-73. doi: 10.1021/jo501269f. Epub 2014 Sep 16.

PMID:
25188775
12.

Synthesis of functionalized spiroindolines via palladium-catalyzed methine C-H arylation.

Saget T, Perez D, Cramer N.

Org Lett. 2013 Mar 15;15(6):1354-7. doi: 10.1021/ol400380y. Epub 2013 Mar 1.

PMID:
23452056
13.

Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.

Sakamoto T, Moriya M, Tsuge H, Takahashi T, Haga Y, Nonoshita K, Okamoto O, Takahashi H, Sakuraba A, Hirohashi T, Shibata T, Kanno T, Ito J, Iwaasa H, Gomori A, Ishihara A, Fukuroda T, Kanatani A, Fukami T.

Bioorg Med Chem. 2009 Jul 15;17(14):5015-26. doi: 10.1016/j.bmc.2009.05.064. Epub 2009 Jun 2.

PMID:
19525116
14.

1'-Methylcyclooctane-1-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-2,2''-dione and 1,1'-dimethylpiperidine-3-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-2'',4-dione.

Suresh J, Suresh Kumar R, Perumal S, Natarajan S.

Acta Crystallogr C. 2007 Sep;63(Pt 9):o538-42. Epub 2007 Aug 17.

PMID:
17762127
15.

Efficient Pd-catalyzed domino synthesis of 1-phenyl-1H-indol-2-amine and 5-amino-indolo[1,2-a]quinazoline derivatives.

Jiang M, Xiang H, Zhu F, Xu X, Deng L, Yang C.

Org Biomol Chem. 2015 Oct 28;13(40):10122-6. doi: 10.1039/c5ob01642h. Epub 2015 Sep 17.

PMID:
26377704
16.

1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo.

Tinker AC, Beaton HG, Boughton-Smith N, Cook TR, Cooper SL, Fraser-Rae L, Hallam K, Hamley P, McInally T, Nicholls DJ, Pimm AD, Wallace AV.

J Med Chem. 2003 Mar 13;46(6):913-6.

PMID:
12620067
17.

Silver-promoted, palladium-catalyzed direct arylation of cyclopropanes: facile access to spiro 3,3'-cyclopropyl oxindoles.

Ladd CL, Sustac Roman D, Charette AB.

Org Lett. 2013 Mar 15;15(6):1350-3. doi: 10.1021/ol4003338. Epub 2013 Mar 1.

PMID:
23452033
18.

An Organocatalysis Based Carbocyclic Spiroindoline Synthesis Enables Facile Structure-Activity Relationship (SAR) Study at C2 Position.

Zheng Y, Cleaveland J, Richardson D, Yuan Y.

Org Lett. 2015 Sep 4;17(17):4240-3. doi: 10.1021/acs.orglett.5b02031. Epub 2015 Aug 14.

PMID:
26273894
19.

Construction of polycyclic spiro-indolines via an intramolecular oxidative coupling/cyclization cascade reaction process.

Fan F, Xie W, Ma D.

Org Lett. 2012 Mar 16;14(6):1405-7. doi: 10.1021/ol3003496. Epub 2012 Mar 8.

PMID:
22400980
20.

Palladium-catalyzed tandem Heck reaction/C-H functionalization--preparation of spiro-indane-oxindoles.

Ruck RT, Huffman MA, Kim MM, Shevlin M, Kandur WV, Davies IW.

Angew Chem Int Ed Engl. 2008;47(25):4711-4. doi: 10.1002/anie.200800549. No abstract available.

PMID:
18491340

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