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Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.

Dong J, Chen Y, Xu X, Jin R, Teng F, Yan F, Tang H, Li P, Sun X, Li Y, Wu H, Zhang Y, Ge Q.

PLoS One. 2013;8(2):e56378. doi: 10.1371/journal.pone.0056378. Epub 2013 Feb 11.


Retention and tolerance of autoreactive CD4(+) recent thymic emigrants in the liver.

Xu X, Zhang S, Jin R, Wang K, Li P, Lin L, Dong J, Hao J, Zhang Y, Sun X, Pang X, Qian X, Zhang J, Wu H, Zhang Y, Ge Q.

J Autoimmun. 2015 Jan;56:87-97. doi: 10.1016/j.jaut.2014.10.006. Epub 2014 Nov 14.


Identification of a developmentally regulated phase of postselection expansion driven by thymic epithelium.

Hare KJ, Wilkinson RW, Jenkinson EJ, Anderson G.

J Immunol. 1998 Apr 15;160(8):3666-72.


Thymic output in aged mice.

Hale JS, Boursalian TE, Turk GL, Fink PJ.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8447-52. Epub 2006 May 22.


The transient expression of C-C chemokine receptor 8 in thymus identifies a thymocyte subset committed to become CD4+ single-positive T cells.

Kremer L, Carramolino L, Goya I, Zaballos A, Gutiérrez J, Moreno-Ortiz M del C, Martínez-A C, Márquez G.

J Immunol. 2001 Jan 1;166(1):218-25.


A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus.

Vianello F, Kraft P, Mok YT, Hart WK, White N, Poznansky MC.

J Immunol. 2005 Oct 15;175(8):5115-25.


MHC class II molecules are required for initiation of positive selection but not during terminal differentiation of human CD4 single positive thymocytes.

Vanhecke D, Verhasselt B, De Smedt M, De Paepe B, Leclercq G, Plum J, Vandekerckhove B.

J Immunol. 1997 Apr 15;158(8):3730-7.


Recent thymic emigrants are distinct from most medullary thymocytes.

Gabor MJ, Godfrey DI, Scollay R.

Eur J Immunol. 1997 Aug;27(8):2010-5.


Liver sinusoidal endothelial cells induce tolerance of autoreactive CD4+ recent thymic emigrants.

Xu X, Jin R, Li M, Wang K, Zhang S, Hao J, Sun X, Zhang Y, Wu H, Zhang J, Ge Q.

Sci Rep. 2016 Jan 22;6:19861. doi: 10.1038/srep19861.


CD69 expression discriminates MHC-dependent and -independent stages of thymocyte positive selection.

Hare KJ, Jenkinson EJ, Anderson G.

J Immunol. 1999 Apr 1;162(7):3978-83.


Redox balance of mouse medullary CD4 single-positive thymocytes.

Jin R, Teng F, Xu X, Yao Y, Zhang S, Sun X, Zhang Y, Ge Q.

Immunol Cell Biol. 2013 Nov-Dec;91(10):634-41. doi: 10.1038/icb.2013.57. Epub 2013 Oct 8.


TCR triggering modulates the responsiveness and homeostatic proliferation of CD4+ thymic emigrants to IL-7 therapy.

Hennion-Tscheltzoff O, Leboeuf D, Gauthier SD, Dupuis M, Assouline B, Grégoire A, Thiant S, Guimond M.

Blood. 2013 Jun 6;121(23):4684-93. doi: 10.1182/blood-2012-09-458174. Epub 2013 Apr 23.


Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis.

Jaleco S, Swainson L, Dardalhon V, Burjanadze M, Kinet S, Taylor N.

J Immunol. 2003 Jul 1;171(1):61-8.


Distinct IL-7 signaling in recent thymic emigrants versus mature naïve T cells controls T-cell homeostasis.

Kim HK, Waickman AT, Castro E, Flomerfelt FA, Hawk NV, Kapoor V, Telford WG, Gress RE.

Eur J Immunol. 2016 Jul;46(7):1669-80. doi: 10.1002/eji.201546214. Epub 2016 May 17.


Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus.

Watanabe N, Wang YH, Lee HK, Ito T, Wang YH, Cao W, Liu YJ.

Nature. 2005 Aug 25;436(7054):1181-5.

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