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Items: 1 to 20 of 122

1.

Conformational transition pathway in the activation process of allosteric glucokinase.

Huang M, Lu S, Shi T, Zhao Y, Chen Y, Li X, Liu X, Huang Z, Zhang J.

PLoS One. 2013;8(2):e55857. doi: 10.1371/journal.pone.0055857. Epub 2013 Feb 7.

2.

Conformational transition pathway in the allosteric process of human glucokinase.

Zhang J, Li C, Chen K, Zhu W, Shen X, Jiang H.

Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13368-73. Epub 2006 Aug 28.

3.

Binding kinetics of glucose and allosteric activators to human glucokinase reveal multiple conformational states.

Antoine M, Boutin JA, Ferry G.

Biochemistry. 2009 Jun 16;48(23):5466-82. doi: 10.1021/bi900374c.

PMID:
19459610
4.

The active conformation of human glucokinase is not altered by allosteric activators.

Petit P, Antoine M, Ferry G, Boutin JA, Lagarde A, Gluais L, Vincentelli R, Vuillard L.

Acta Crystallogr D Biol Crystallogr. 2011 Nov;67(Pt 11):929-35. doi: 10.1107/S0907444911036729. Epub 2011 Oct 19.

PMID:
22101819
5.

Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis.

Heredia VV, Thomson J, Nettleton D, Sun S.

Biochemistry. 2006 Jun 20;45(24):7553-62.

PMID:
16768451
6.

Catalytic activation of human glucokinase by substrate binding: residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions.

Molnes J, Bjørkhaug L, Søvik O, Njølstad PR, Flatmark T.

FEBS J. 2008 May;275(10):2467-81. doi: 10.1111/j.1742-4658.2008.06391.x. Epub 2008 Apr 7.

7.

Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase.

Choi JM, Seo MH, Kyeong HH, Kim E, Kim HS.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10171-6. doi: 10.1073/pnas.1300457110. Epub 2013 Jun 3.

8.

Modulation of glucokinase by glucose, small-molecule activator and glucokinase regulatory protein: steady-state kinetic and cell-based analysis.

Bourbonais FJ, Chen J, Huang C, Zhang Y, Pfefferkorn JA, Landro JA.

Biochem J. 2012 Feb 1;441(3):881-7. doi: 10.1042/BJ20110721.

PMID:
22044397
9.

Lys169 of human glucokinase is a determinant for glucose phosphorylation: implication for the atomic mechanism of glucokinase catalysis.

Zhang J, Li C, Shi T, Chen K, Shen X, Jiang H.

PLoS One. 2009 Jul 20;4(7):e6304. doi: 10.1371/journal.pone.0006304.

10.

Insights into mechanism of glucokinase activation: observation of multiple distinct protein conformations.

Liu S, Ammirati MJ, Song X, Knafels JD, Zhang J, Greasley SE, Pfefferkorn JA, Qiu X.

J Biol Chem. 2012 Apr 20;287(17):13598-610. doi: 10.1074/jbc.M111.274126. Epub 2012 Feb 1.

11.

Glucose modulation of glucokinase activation by small molecules.

Ralph EC, Thomson J, Almaden J, Sun S.

Biochemistry. 2008 Apr 29;47(17):5028-36. doi: 10.1021/bi702516y. Epub 2008 Mar 28.

PMID:
18370405
12.

Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase.

Kamata K, Mitsuya M, Nishimura T, Eiki J, Nagata Y.

Structure. 2004 Mar;12(3):429-38.

13.

Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations.

Heredia VV, Carlson TJ, Garcia E, Sun S.

J Biol Chem. 2006 Dec 29;281(52):40201-7. Epub 2006 Nov 2.

14.

Homotropic allosteric regulation in monomeric mammalian glucokinase.

Larion M, Miller BG.

Arch Biochem Biophys. 2012 Mar 15;519(2):103-11. doi: 10.1016/j.abb.2011.11.007. Epub 2011 Nov 15. Review.

15.

Mutational analysis of allosteric activation and inhibition of glucokinase.

Zelent B, Odili S, Buettger C, Zelent DK, Chen P, Fenner D, Bass J, Stanley C, Laberge M, Vanderkooi JM, Sarabu R, Grimsby J, Matschinsky FM.

Biochem J. 2011 Dec 1;440(2):203-15. doi: 10.1042/BJ20110440.

16.

A pre-steady state analysis of ligand binding to human glucokinase: evidence for a preexisting equilibrium.

Kim YB, Kalinowski SS, Marcinkeviciene J.

Biochemistry. 2007 Feb 6;46(5):1423-31.

PMID:
17260972
17.

Discovery of Small-Molecule Glucokinase Regulatory Protein Modulators That Restore Glucokinase Activity.

Chen K, Michelsen K, Kurzeja RJ, Han J, Vazir M, St Jean DJ Jr, Hale C, Wahl RC.

J Biomol Screen. 2014 Aug;19(7):1014-23. doi: 10.1177/1087057114530468. Epub 2014 Apr 9.

PMID:
24717911
18.

Identification and analysis of novel R308K mutation in glucokinase of type 2 diabetic patient and its kinetic correlation.

Yellapu NK, Valasani KR, Pasupuleti SK, Gopal S, Potukuchi Venkata Gurunadha Krishna S, Matcha B.

Biotechnol Appl Biochem. 2014 Sep-Oct;61(5):572-81. doi: 10.1002/bab.1209. Epub 2014 Mar 25.

PMID:
24447076
19.

Thermal stability of glucokinase (GK) as influenced by the substrate glucose, an allosteric glucokinase activator drug (GKA) and the osmolytes glycerol and urea.

Zelent B, Buettger C, Grimsby J, Sarabu R, Vanderkooi JM, Wand AJ, Matschinsky FM.

Biochim Biophys Acta. 2012 May;1824(5):769-84. doi: 10.1016/j.bbapap.2012.03.003. Epub 2012 Mar 16.

20.

Binding of ATP at the active site of human pancreatic glucokinase--nucleotide-induced conformational changes with possible implications for its kinetic cooperativity.

Molnes J, Teigen K, Aukrust I, Bjørkhaug L, Søvik O, Flatmark T, Njølstad PR.

FEBS J. 2011 Jul;278(13):2372-86. doi: 10.1111/j.1742-4658.2011.08160.x. Epub 2011 May 31.

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