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Items: 1 to 20 of 85

1.

Activation of apoptosis in hepatocellular carcinoma by the Chinese traditional medicine Hu Qisan.

Zeng X, Li X, Xue X, Shi ZM, Feng P, Wang P, Wang XJ.

Exp Ther Med. 2013 Mar;5(3):695-700. Epub 2012 Dec 18.

2.

Omi/HtrA2 pro-apoptotic marker differs in various hepatocellular carcinoma cell lines owing to ped/pea-15 expression level.

Xu Z, Chen Y, Xu G, Peng C, Liu E, Li Y, Niu J, Li C.

Oncol Rep. 2015 Feb;33(2):905-12. doi: 10.3892/or.2014.3656. Epub 2014 Dec 8.

PMID:
25484138
3.

Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways.

Suzuki Y, Takahashi-Niki K, Akagi T, Hashikawa T, Takahashi R.

Cell Death Differ. 2004 Feb;11(2):208-16.

4.

Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injury.

Wang K, Zhang J, Liu J, Tian J, Wu Y, Wang X, Quan L, Xu H, Wang W, Liu H.

Age (Dordr). 2013 Jun;35(3):733-46. doi: 10.1007/s11357-012-9406-x. Epub 2012 Apr 26.

5.

Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis.

Zhao J, Chen X, Lin W, Wu G, Zhuang Q, Zhong X, Hong Z, Peng J.

Int J Oncol. 2013 Mar;42(3):971-8. doi: 10.3892/ijo.2013.1779. Epub 2013 Jan 18.

PMID:
23338043
6.

High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma.

Duan XY, Pan Q, Yan SY, Ding WJ, Fan JG, Qiao L.

BMC Gastroenterol. 2014 Nov 20;14:195. doi: 10.1186/s12876-014-0195-9.

7.

Modulation of energy metabolic enzyme expression in N-nitrosodiethylamine-mediated hepatocarcinogenesis by Chinese herbs, Huqi San.

Wen Z, Shi Z, Feng P, Xue X, Dong K, Wang X.

Biofactors. 2008;34(4):303-12. doi: 10.3233/BIO-2009-1084.

PMID:
19850985
8.

The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion.

Althaus J, Siegelin MD, Dehghani F, Cilenti L, Zervos AS, Rami A.

Neurochem Int. 2007 Jan;50(1):172-80. Epub 2006 Sep 15.

PMID:
16978742
9.

Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2.

Srinivasula SM, Gupta S, Datta P, Zhang Z, Hegde R, Cheong N, Fernandes-Alnemri T, Alnemri ES.

J Biol Chem. 2003 Aug 22;278(34):31469-72. Epub 2003 Jun 30.

10.

HQS-3, a newly synthesized flavonoid, possesses potent anti-tumor effect in vivo and in vitro.

Zhou Y, Lu N, Zhang H, Wei L, Tao L, Dai Q, Zhao L, Lin B, Ding Q, Guo Q.

Eur J Pharm Sci. 2013 Jul 16;49(4):649-58. doi: 10.1016/j.ejps.2013.04.016. Epub 2013 Apr 22.

PMID:
23619285
11.

Regulation of HtrA2/Omi by X-linked inhibitor of apoptosis protein in chemoresistance in human ovarian cancer cells.

Yang X, Xing H, Gao Q, Chen G, Lu Y, Wang S, Ma D.

Gynecol Oncol. 2005 May;97(2):413-21.

PMID:
15863139
13.

Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats.

Fujii Y, Segawa R, Kimura M, Wang L, Ishii Y, Yamamoto R, Morita R, Mitsumori K, Shibutani M.

Chem Biol Interact. 2013 Sep 25;205(2):108-18. doi: 10.1016/j.cbi.2013.06.017. Epub 2013 Jul 2.

PMID:
23830814
14.

Enhanced HtrA2/Omi expression in oxidative injury to retinal pigment epithelial cells and murine models of neurodegeneration.

Ding X, Patel M, Shen D, Herzlich AA, Cao X, Villasmil R, Klupsch K, Tuo J, Downward J, Chan CC.

Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4957-66. doi: 10.1167/iovs.09-3381. Epub 2009 May 14.

15.
16.

Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet).

Taha MM, Abdul AB, Abdullah R, Ibrahim TA, Abdelwahab SI, Mohan S.

Chem Biol Interact. 2010 Aug 5;186(3):295-305. doi: 10.1016/j.cbi.2010.04.029. Epub 2010 May 7.

PMID:
20452335
17.

JA, a new type of polyunsaturated fatty acid isolated from Juglans mandshurica Maxim, limits the survival and induces apoptosis of heptocarcinoma cells.

Gao XL, Lin H, Zhao W, Hou YQ, Bao YL, Song ZB, Sun LG, Tian SY, Liu B, Li YX.

Apoptosis. 2016 Mar;21(3):340-50. doi: 10.1007/s10495-015-1202-5.

PMID:
26621097
19.

Protective effects of Celastrol on diethylnitrosamine-induced hepatocellular carcinoma in rats and its mechanisms.

Chang W, He W, Li PP, Song SS, Yuan PF, Lu JT, Wei W.

Eur J Pharmacol. 2016 Aug 5;784:173-80. doi: 10.1016/j.ejphar.2016.04.045. Epub 2016 May 12.

PMID:
27181068
20.

NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

National Toxicology Program .

Natl Toxicol Program Tech Rep Ser. 1993 Sep;422:1-340.

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