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Items: 1 to 20 of 302

1.

β-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1.

Alemayehu M, Dragan M, Pape C, Siddiqui I, Sacks DB, Di Guglielmo GM, Babwah AV, Bhattacharya M.

PLoS One. 2013;8(2):e56174. doi: 10.1371/journal.pone.0056174.

2.

Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells.

Li TT, Alemayehu M, Aziziyeh AI, Pape C, Pampillo M, Postovit LM, Mills GB, Babwah AV, Bhattacharya M.

Mol Cancer Res. 2009 Jul;7(7):1064-77. doi: 10.1158/1541-7786.MCR-08-0578.

3.

LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells.

Chen M, Towers LN, O'Connor KL.

Am J Physiol Cell Physiol. 2007 May;292(5):C1927-33.

4.

Negative regulation of cell motile and invasive activities by lysophosphatidic acid receptor-3 in colon cancer HCT116 cells.

Fukui R, Tanabe E, Kitayoshi M, Yoshikawa K, Fukushima N, Tsujiuchi T.

Tumour Biol. 2012 Dec;33(6):1899-905. doi: 10.1007/s13277-012-0450-z.

PMID:
22763559
5.

KISS1R induces invasiveness of estrogen receptor-negative human mammary epithelial and breast cancer cells.

Cvetkovic D, Dragan M, Leith SJ, Mir ZM, Leong HS, Pampillo M, Lewis JD, Babwah AV, Bhattacharya M.

Endocrinology. 2013 Jun;154(6):1999-2014. doi: 10.1210/en.2012-2164.

PMID:
23525242
6.

Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion.

Shida D, Fang X, Kordula T, Takabe K, Lépine S, Alvarez SE, Milstien S, Spiegel S.

Cancer Res. 2008 Aug 15;68(16):6569-77. doi: 10.1158/0008-5472.CAN-08-0411.

7.

IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells.

Zoheir KM, Abd-Rabou AA, Harisa GI, Kumar A, Ahmad SF, Ansari MA, Abd-Allah AR.

Tumour Biol. 2016 Oct;37(10):13927-13939.

PMID:
27488117
8.

Lysophosphatidic acid suppresses endothelial cell CD36 expression and promotes angiogenesis via a PKD-1-dependent signaling pathway.

Ren B, Hale J, Srikanthan S, Silverstein RL.

Blood. 2011 Jun 2;117(22):6036-45. doi: 10.1182/blood-2010-12-326017.

9.

A novel biomarker C6orf106 promotes the malignant progression of breast cancer.

Jiang G, Zhang X, Zhang Y, Wang L, Fan C, Xu H, Miao Y, Wang E.

Tumour Biol. 2015 Sep;36(10):7881-9. doi: 10.1007/s13277-015-3500-5.

PMID:
25953261
10.
12.

Bioactive lipids lysophosphatidic acid and sphingosine 1-phosphate mediate breast cancer cell biological functions through distinct mechanisms.

Boucharaba A, Guillet B, Menaa F, Hneino M, van Wijnen AJ, Clézardin P, Peyruchaud O.

Oncol Res. 2009;18(4):173-84. Erratum in: Oncol Res. 2009;18(7):357. Philippe, Clézardin [corrected to Clézardin, Philippe]; Oliver, Peyruchaud [corrected to Peyruchaud, Oliver].

PMID:
20112503
13.

LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.

Komachi M, Tomura H, Malchinkhuu E, Tobo M, Mogi C, Yamada T, Kimura T, Kuwabara A, Ohta H, Im DS, Kurose H, Takeyoshi I, Sato K, Okajima F.

Carcinogenesis. 2009 Mar;30(3):457-65. doi: 10.1093/carcin/bgp011.

PMID:
19129242
14.
15.

Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells.

Sun K, Duan X, Cai H, Liu X, Yang Y, Li M, Zhang X, Wang J.

Clin Exp Med. 2016 Feb;16(1):37-47. doi: 10.1007/s10238-015-0336-7.

PMID:
25596714
16.

The gep proto-oncogene Gα13 mediates lysophosphatidic acid-mediated migration of pancreatic cancer cells.

Gardner JA, Ha JH, Jayaraman M, Dhanasekaran DN.

Pancreas. 2013 Jul;42(5):819-28. doi: 10.1097/MPA.0b013e318279c577.

17.

Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.

Casteel DE, Turner S, Schwappacher R, Rangaswami H, Su-Yuo J, Zhuang S, Boss GR, Pilz RB.

J Biol Chem. 2012 Nov 2;287(45):38367-78. doi: 10.1074/jbc.M112.377499.

18.
19.

Lysophosphatidic acid stimulates cell migration, invasion, and colony formation as well as tumorigenesis/metastasis of mouse ovarian cancer in immunocompetent mice.

Li H, Wang D, Zhang H, Kirmani K, Zhao Z, Steinmetz R, Xu Y.

Mol Cancer Ther. 2009 Jun;8(6):1692-701. doi: 10.1158/1535-7163.MCT-08-1106.

20.

Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers.

David M, Sahay D, Mege F, Descotes F, Leblanc R, Ribeiro J, Clézardin P, Peyruchaud O.

PLoS One. 2014 May 14;9(5):e97771. doi: 10.1371/journal.pone.0097771.

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