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Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis.

Ghosh S, DeCoffe D, Brown K, Rajendiran E, Estaki M, Dai C, Yip A, Gibson DL.

PLoS One. 2013;8(2):e55468. doi: 10.1371/journal.pone.0055468. Epub 2013 Feb 6.


Dietary oils modify the host immune response and colonic tissue damage following Citrobacter rodentium infection in mice.

Hekmatdoost A, Wu X, Morampudi V, Innis SM, Jacobson K.

Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G917-28. doi: 10.1152/ajpgi.00292.2012. Epub 2013 Mar 21.


Diets rich in n-6 PUFA induce intestinal microbial dysbiosis in aged mice.

Ghosh S, Molcan E, DeCoffe D, Dai C, Gibson DL.

Br J Nutr. 2013 Aug 28;110(3):515-23. doi: 10.1017/S0007114512005326. Epub 2013 Jan 8.


Intestinal anti-inflammatory activity of combined quercitrin and dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, in rats with DSS-induced colitis.

Camuesco D, Comalada M, Concha A, Nieto A, Sierra S, Xaus J, Zarzuelo A, Gálvez J.

Clin Nutr. 2006 Jun;25(3):466-76. Epub 2006 May 15.


A soybean and fish oil mixture with different n-6/n-3 PUFA ratios modulates the inflammatory reaction in mice with dextran sulfate sodium-induced acute colitis.

Huang CH, Hou YC, Yeh CL, Yeh SL.

Clin Nutr. 2015 Oct;34(5):1018-24. doi: 10.1016/j.clnu.2014.11.008. Epub 2014 Nov 18.


Dietary vitamin D3 deficiency alters intestinal mucosal defense and increases susceptibility to Citrobacter rodentium-induced colitis.

Ryz NR, Lochner A, Bhullar K, Ma C, Huang T, Bhinder G, Bosman E, Wu X, Innis SM, Jacobson K, Vallance BA.

Am J Physiol Gastrointest Liver Physiol. 2015 Nov 1;309(9):G730-42. doi: 10.1152/ajpgi.00006.2015. Epub 2015 Sep 3.


Medicinal lavender modulates the enteric microbiota to protect against Citrobacter rodentium-induced colitis.

Baker J, Brown K, Rajendiran E, Yip A, DeCoffe D, Dai C, Molcan E, Chittick SA, Ghosh S, Mahmoud S, Gibson DL.

Am J Physiol Gastrointest Liver Physiol. 2012 Oct;303(7):G825-36. doi: 10.1152/ajpgi.00327.2011. Epub 2012 Jul 19.


Dietary flaxseed intake exacerbates acute colonic mucosal injury and inflammation induced by dextran sodium sulfate.

Zarepoor L, Lu JT, Zhang C, Wu W, Lepp D, Robinson L, Wanasundara J, Cui S, Villeneuve S, Fofana B, Tsao R, Wood GA, Power KA.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 15;306(12):G1042-55. doi: 10.1152/ajpgi.00253.2013. Epub 2014 Apr 24.


[Effects of the diet ratio of polyunsaturated fatty acids ω-3/ω-6 on experimental colitis in mice].

Tian Y, Tian YL, Li JX, Dai Y, Wang HH, Liu XG.

Beijing Da Xue Xue Bao. 2013 Apr 18;45(2):227-32. Chinese.


Maternal and neonatal dietary intake of balanced n-6/n-3 fatty acids modulates experimental colitis in young adult rats.

Reddy KV, Naidu KA.

Eur J Nutr. 2016 Aug;55(5):1875-90. doi: 10.1007/s00394-015-1004-0. Epub 2015 Aug 6.


Dietary Lipid Type, Rather Than Total Number of Calories, Alters Outcomes of Enteric Infection in Mice.

DeCoffe D, Quin C, Gill SK, Tasnim N, Brown K, Godovannyi A, Dai C, Abulizi N, Chan YK, Ghosh S, Gibson DL.

J Infect Dis. 2016 Jun 1;213(11):1846-56. doi: 10.1093/infdis/jiw084. Epub 2016 Apr 10.


Effect of dietary fat on intestinal inflammatory diseases.

Hokari R, Matsunaga H, Miura S.

J Gastroenterol Hepatol. 2013 Dec;28 Suppl 4:33-6. doi: 10.1111/jgh.12252. Review.


Fish oil enhances intestinal integrity and inhibits TLR4 and NOD2 signaling pathways in weaned pigs after LPS challenge.

Liu Y, Chen F, Odle J, Lin X, Jacobi SK, Zhu H, Wu Z, Hou Y.

J Nutr. 2012 Nov;142(11):2017-24. doi: 10.3945/jn.112.164947. Epub 2012 Sep 26.


Omega-3 fatty acids exacerbate DSS-induced colitis through decreased adiponectin in colonic subepithelial myofibroblasts.

Matsunaga H, Hokari R, Kurihara C, Okada Y, Takebayashi K, Okudaira K, Watanabe C, Komoto S, Nakamura M, Tsuzuki Y, Kawaguchi A, Nagao S, Itoh K, Miura S.

Inflamm Bowel Dis. 2008 Oct;14(10):1348-57. doi: 10.1002/ibd.20491.


Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis.

Camuesco D, Gálvez J, Nieto A, Comalada M, Rodríguez-Cabezas ME, Concha A, Xaus J, Zarzuelo A.

J Nutr. 2005 Apr;135(4):687-94.


Probiotics are effective for the prevention and treatment of Citrobacter rodentium-induced colitis in mice.

Rodrigues DM, Sousa AJ, Johnson-Henry KC, Sherman PM, Gareau MG.

J Infect Dis. 2012 Jul 1;206(1):99-109. doi: 10.1093/infdis/jis177. Epub 2012 Mar 19.


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