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3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation.

Yoon JS, Lee JH, Tweedie D, Mughal MR, Chigurupati S, Greig NH, Mattson MP.

J Neurosci Res. 2013 May;91(5):671-80. doi: 10.1002/jnr.23190. Epub 2013 Feb 13.


Mindin is a critical mediator of ischemic brain injury in an experimental stroke model.

Wang L, Lu Y, Zhang X, Zhang Y, Jiang D, Dong X, Deng S, Yang L, Guan Y, Zhu L, Zhou Y, Zhang X, Li H.

Exp Neurol. 2013 Sep;247:506-16. doi: 10.1016/j.expneurol.2013.01.022. Epub 2013 Jan 27.


Omega-3 polyunsaturated fatty acids ameliorate neuroinflammation and mitigate ischemic stroke damage through interactions with astrocytes and microglia.

Zendedel A, Habib P, Dang J, Lammerding L, Hoffmann S, Beyer C, Slowik A.

J Neuroimmunol. 2015 Jan 15;278:200-11. doi: 10.1016/j.jneuroim.2014.11.007. Epub 2014 Nov 14.


TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation.

Belarbi K, Jopson T, Tweedie D, Arellano C, Luo W, Greig NH, Rosi S.

J Neuroinflammation. 2012 Jan 25;9:23. doi: 10.1186/1742-2094-9-23.


Neuroprotection against focal ischemic brain injury by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.

Luo Y, Yin W, Signore AP, Zhang F, Hong Z, Wang S, Graham SH, Chen J.

J Neurochem. 2006 Apr;97(2):435-48. Epub 2006 Mar 15.


Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease.

Tweedie D, Ferguson RA, Fishman K, Frankola KA, Van Praag H, Holloway HW, Luo W, Li Y, Caracciolo L, Russo I, Barlati S, Ray B, Lahiri DK, Bosetti F, Greig NH, Rosi S.

J Neuroinflammation. 2012 May 29;9:106. doi: 10.1186/1742-2094-9-106.


Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms.

Ikeda-Matsuo Y, Tanji H, Narumiya S, Sasaki Y.

J Neuroimmunol. 2011 Sep 15;238(1-2):34-43. doi: 10.1016/j.jneuroim.2011.06.014. Epub 2011 Jul 30.


Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB.

Sun M, Zhao Y, Gu Y, Xu C.

Amino Acids. 2012 May;42(5):1735-47. doi: 10.1007/s00726-011-0885-3. Epub 2011 Mar 16.


Effects of the PPAR-beta agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination.

Defaux A, Zurich MG, Braissant O, Honegger P, Monnet-Tschudi F.

J Neuroinflammation. 2009 May 7;6:15. doi: 10.1186/1742-2094-6-15.


Adjudin protects against cerebral ischemia reperfusion injury by inhibition of neuroinflammation and blood-brain barrier disruption.

Liu T, Zhang T, Yu H, Shen H, Xia W.

J Neuroinflammation. 2014 Jun 14;11:107. doi: 10.1186/1742-2094-11-107.


Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease.

Vitner EB, Farfel-Becker T, Eilam R, Biton I, Futerman AH.

Brain. 2012 Jun;135(Pt 6):1724-35. doi: 10.1093/brain/aws095. Epub 2012 May 7.


Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke.

Raza SS, Khan MM, Ahmad A, Ashafaq M, Khuwaja G, Tabassum R, Javed H, Siddiqui MS, Safhi MM, Islam F.

Brain Res. 2011 Oct 28;1420:93-105. doi: 10.1016/j.brainres.2011.08.047. Epub 2011 Aug 27.


Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion.

Liu Y, Tang G, Li Y, Wang Y, Chen X, Gu X, Zhang Z, Wang Y, Yang GY.

J Neuroinflammation. 2014 Oct 15;11:177. doi: 10.1186/s12974-014-0177-4.


NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects.

Xue H, Zhang XY, Liu JM, Song Y, Liu TT, Chen D.

Brain Res. 2013 Jun 21;1516:83-92. doi: 10.1016/j.brainres.2013.04.016. Epub 2013 Apr 17.


Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in rats.

Kong LL, Wang ZY, Han N, Zhuang XM, Wang ZZ, Li H, Chen NH.

J Neuroinflammation. 2014 Jun 20;11:112. doi: 10.1186/1742-2094-11-112.


Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.

Khan M, Sekhon B, Jatana M, Giri S, Gilg AG, Sekhon C, Singh I, Singh AK.

J Neurosci Res. 2004 May 15;76(4):519-27.


Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke.

Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Lizasoain I.

Circulation. 2007 Mar 27;115(12):1599-608. Epub 2007 Mar 19.


Treatment with AMD3100 attenuates the microglial response and improves outcome after experimental stroke.

Walter HL, van der Maten G, Antunes AR, Wieloch T, Ruscher K.

J Neuroinflammation. 2015 Feb 7;12:24. doi: 10.1186/s12974-014-0232-1.

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