Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 97

1.

Probing the metabolism of an inducible mammalian expression system using extracellular isotopomer analysis.

Sheikholeslami Z, Jolicoeur M, Henry O.

J Biotechnol. 2013 Apr 15;164(4):469-78. doi: 10.1016/j.jbiotec.2013.01.025.

PMID:
23403402
2.

Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption.

Martínez VS, Dietmair S, Quek LE, Hodson MP, Gray P, Nielsen LK.

Biotechnol Bioeng. 2013 Feb;110(2):660-6. doi: 10.1002/bit.24728.

PMID:
22991240
3.

Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry.

Ahn WS, Antoniewicz MR.

Metab Eng. 2011 Sep;13(5):598-609. doi: 10.1016/j.ymben.2011.07.002.

PMID:
21821143
4.
5.

Metabolic flux analysis of CHO cells in perfusion culture by metabolite balancing and 2D [13C, 1H] COSY NMR spectroscopy.

Goudar C, Biener R, Boisart C, Heidemann R, Piret J, de Graaf A, Konstantinov K.

Metab Eng. 2010 Mar;12(2):138-49. doi: 10.1016/j.ymben.2009.10.007.

PMID:
19896555
6.

Elucidating the role of copper in CHO cell energy metabolism using (13)C metabolic flux analysis.

Nargund S, Qiu J, Goudar CT.

Biotechnol Prog. 2015 Sep-Oct;31(5):1179-86. doi: 10.1002/btpr.2131.

PMID:
26097228
7.

Comparative metabolite analysis to understand lactate metabolism shift in Chinese hamster ovary cell culture process.

Luo J, Vijayasankaran N, Autsen J, Santuray R, Hudson T, Amanullah A, Li F.

Biotechnol Bioeng. 2012 Jan;109(1):146-56. doi: 10.1002/bit.23291.

PMID:
21964570
8.

Metabolic analysis of antibody producing CHO cells in fed-batch production.

Dean J, Reddy P.

Biotechnol Bioeng. 2013 Jun;110(6):1735-47. doi: 10.1002/bit.24826.

PMID:
23296898
9.

Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis.

Strigun A, Wahrheit J, Niklas J, Heinzle E, Noor F.

Toxicol Sci. 2012 Feb;125(2):595-606. doi: 10.1093/toxsci/kfr298.

PMID:
22048646
10.

Enhanced production and isotope enrichment of recombinant glycoproteins produced in cultured mammalian cells.

Skelton D, Goodyear A, Ni D, Walton WJ, Rolle M, Hare JT, Logan TM.

J Biomol NMR. 2010 Oct;48(2):93-102. doi: 10.1007/s10858-010-9440-x.

PMID:
20683638
11.

Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases.

Zhou M, Crawford Y, Ng D, Tung J, Pynn AF, Meier A, Yuk IH, Vijayasankaran N, Leach K, Joly J, Snedecor B, Shen A.

J Biotechnol. 2011 Apr 20;153(1-2):27-34. doi: 10.1016/j.jbiotec.2011.03.003.

PMID:
21392546
12.

Metabolic flux analysis of CHO cell metabolism in the late non-growth phase.

Sengupta N, Rose ST, Morgan JA.

Biotechnol Bioeng. 2011 Jan;108(1):82-92. doi: 10.1002/bit.22890.

PMID:
20672285
13.

Quantification of metabolic limitations during recombinant protein production in Escherichia coli.

Heyland J, Blank LM, Schmid A.

J Biotechnol. 2011 Sep 10;155(2):178-84. doi: 10.1016/j.jbiotec.2011.06.016.

PMID:
21723332
14.

Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis.

Henry O, Jolicoeur M, Kamen A.

Bioprocess Biosyst Eng. 2011 Mar;34(3):263-73. doi: 10.1007/s00449-010-0468-9.

PMID:
20848294
15.

Parallel labeling experiments with [1,2-(13)C]glucose and [U-(13)C]glutamine provide new insights into CHO cell metabolism.

Ahn WS, Antoniewicz MR.

Metab Eng. 2013 Jan;15:34-47. doi: 10.1016/j.ymben.2012.10.001.

PMID:
23111062
16.

Isotopomer distributions in amino acids from a highly expressed protein as a proxy for those from total protein.

Shaikh AS, Tang YJ, Mukhopadhyay A, Keasling JD.

Anal Chem. 2008 Feb 1;80(3):886-90. doi: 10.1021/ac071445+.

PMID:
18179240
17.

Isotopomer analysis of myocardial substrate metabolism: a systems biology approach.

Vo TD, Palsson BO.

Biotechnol Bioeng. 2006 Dec 5;95(5):972-83.

PMID:
16878330
18.

A detailed metabolic flux analysis of an underdetermined network of CHO cells.

Zamorano F, Wouwer AV, Bastin G.

J Biotechnol. 2010 Dec;150(4):497-508. doi: 10.1016/j.jbiotec.2010.09.944.

PMID:
20869402
19.
20.

Metabolic flux analysis in mammalian cell culture.

Quek LE, Dietmair S, Krömer JO, Nielsen LK.

Metab Eng. 2010 Mar;12(2):161-71. doi: 10.1016/j.ymben.2009.09.002. Review.

PMID:
19833223
Items per page

Supplemental Content

Support Center