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Items: 1 to 20 of 95

1.

Evaluation of nasal epithelium sampling as a tool in the preclinical development of siRNA-based therapeutics for asthma.

Healey GD, Evans N, Hopkin JM, Davies G, Walker W.

J Cell Mol Med. 2013 Mar;17(3):356-64. doi: 10.1111/jcmm.12014. Epub 2013 Feb 13.

2.

Development of pre-clinical models for evaluating the therapeutic potential of candidate siRNA targeting STAT6.

Healey GD, Lockridge JA, Zinnen S, Hopkin JM, Richards I, Walker W.

PLoS One. 2014 Feb 27;9(2):e90338. doi: 10.1371/journal.pone.0090338. eCollection 2014.

3.

RNA interference of STAT6 rapidly attenuates ongoing interleukin-13-mediated events in lung epithelial cells.

Walker W, Healey GD, Hopkin JM.

Immunology. 2009 Jun;127(2):256-66. doi: 10.1111/j.1365-2567.2008.02951.x. Epub 2008 Oct 29.

4.

STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction.

Rosen MJ, Frey MR, Washington MK, Chaturvedi R, Kuhnhein LA, Matta P, Revetta FL, Wilson KT, Polk DB.

Inflamm Bowel Dis. 2011 Nov;17(11):2224-34. doi: 10.1002/ibd.21628. Epub 2011 Feb 9.

5.

Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice.

Darcan-Nicolaisen Y, Meinicke H, Fels G, Hegend O, Haberland A, Kühl A, Loddenkemper C, Witzenrath M, Kube S, Henke W, Hamelmann E.

J Immunol. 2009 Jun 15;182(12):7501-8. doi: 10.4049/jimmunol.0713433.

6.

[Expression of signal transducer and activator of transcription 6 in rat asthma model and the modulatory effect of dexamethasone].

Li CC, Ye LP, Chen XF, Li SB, Cai XH, Dong L, Luo YC, Zhang ZX.

Zhonghua Er Ke Za Zhi. 2005 Jul;43(7):521-5. Chinese.

PMID:
16083555
7.

Small interfering RNA against transcription factor STAT6 leads to increased cholesterol synthesis in lung cancer cell lines.

Dubey R, Chhabra R, Saini N.

PLoS One. 2011;6(12):e28509. doi: 10.1371/journal.pone.0028509. Epub 2011 Dec 5.

8.

Vitamin E forms inhibit IL-13/STAT6-induced eotaxin-3 secretion by up-regulation of PAR4, an endogenous inhibitor of atypical PKC in human lung epithelial cells.

Wang Y, Moreland M, Wagner JG, Ames BN, Illek B, Peden DB, Jiang Q.

J Nutr Biochem. 2012 Jun;23(6):602-8. doi: 10.1016/j.jnutbio.2011.03.003. Epub 2011 Jul 20.

9.

Potentiation of IL-19 expression in airway epithelia by IL-17A and IL-4/IL-13: important implications in asthma.

Huang F, Wachi S, Thai P, Loukoianov A, Tan KH, Forteza RM, Wu R.

J Allergy Clin Immunol. 2008 Jun;121(6):1415-21, 1421.e1-3. doi: 10.1016/j.jaci.2008.04.016.

10.
11.

Activation of the interleukin-4/signal transducer and activator of transcription 6 signaling pathway and homeodomain-interacting protein kinase 2 production by tonsillar mononuclear cells in IgA nephropathy.

He L, Peng Y, Liu H, Yin W, Chen X, Peng X, Shao J, Liu Y, Liu F.

Am J Nephrol. 2013;38(4):321-32. doi: 10.1159/000355393. Epub 2013 Oct 4.

PMID:
24107646
12.

Gene-expression profiles in human nasal polyp tissues and identification of genetic susceptibility in aspirin-intolerant asthma.

Sekigawa T, Tajima A, Hasegawa T, Hasegawa Y, Inoue H, Sano Y, Matsune S, Kurono Y, Inoue I.

Clin Exp Allergy. 2009 Jul;39(7):972-81. doi: 10.1111/j.1365-2222.2009.03229.x. Epub 2009 Mar 27.

PMID:
19489917
13.

Expression of eotaxins in the material from nasal brushing in asthma, allergic rhinitis and COPD patients.

Paplińska M, Hermanowicz-Salamon J, Nejman-Gryz P, Białek-Gosk K, Rubinsztajn R, Arcimowicz M, Placha G, Góra J, Chazan R, Grubek-Jaworska H.

Cytokine. 2012 Nov;60(2):393-9. doi: 10.1016/j.cyto.2012.07.001. Epub 2012 Jul 28.

PMID:
22846146
14.
15.

Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB.

Xie T, Luo G, Zhang Y, Wang X, Wang X, Wu M, Li G.

Clin Exp Allergy. 2015 Dec;45(12):1812-22. doi: 10.1111/cea.12606.

PMID:
26245530
16.

In vivo expression of signal transducer and activator of transcription factor 6 (STAT6) in nasal mucosa from atopic allergic rhinitis: effect of topical corticosteroids.

Ghaffar O, Christodoulopoulos P, Lamkhioued B, Wright E, Ihaku D, Nakamura Y, Frenkiel S, Hamid Q.

Clin Exp Allergy. 2000 Jan;30(1):86-93.

PMID:
10606935
17.

[Histologic expressions of IL-4/STAT6 in nasal mucosa of guinea pig allergic rhinitis models and effect of glucocorticoid on them].

Zhang H, Geng M, Yan B, Lu X.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Apr;26(8):364-7. Chinese.

PMID:
22730821
18.

[Impact of STAT6 signaling pathway blockade on apoptosis of human colon cancer cells].

Zhang MS, Zhou YF, Xie CH, Zhang WJ, Zhou FX, Qu XJ.

Zhonghua Yi Xue Za Zhi. 2006 Jan 10;86(2):76-81. Chinese.

PMID:
16620708
19.

IL-4-induced Stat6 activities affect apoptosis and gene expression in breast cancer cells.

Zhang WJ, Li BH, Yang XZ, Li PD, Yuan Q, Liu XH, Xu SB, Zhang Y, Yuan J, Gerhard GS, Masker KK, Dong C, Koltun WA, Chorney MJ.

Cytokine. 2008 Apr;42(1):39-47. doi: 10.1016/j.cyto.2008.01.016. Epub 2008 Mar 14.

PMID:
18342537
20.

Interferon-gamma inhibits STAT6 signal transduction and gene expression in human airway epithelial cells.

Heller NM, Matsukura S, Georas SN, Boothby MR, Rothman PB, Stellato C, Schleimer RP.

Am J Respir Cell Mol Biol. 2004 Nov;31(5):573-82. Epub 2004 Aug 5.

PMID:
15297269

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