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Items: 1 to 20 of 148

1.

Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration.

Phillips KL, Jordan-Mahy N, Nicklin MJ, Le Maitre CL.

Ann Rheum Dis. 2013 Nov;72(11):1860-7. doi: 10.1136/annrheumdis-2012-202266. Epub 2013 Feb 9.

PMID:
23396662
2.

Mechanical destabilization induced by controlled annular incision of the intervertebral disc dysregulates metalloproteinase expression and induces disc degeneration.

Melrose J, Shu C, Young C, Ho R, Smith MM, Young AA, Smith SS, Gooden B, Dart A, Podadera J, Appleyard RC, Little CB.

Spine (Phila Pa 1976). 2012 Jan 1;37(1):18-25. doi: 10.1097/BRS.0b013e31820cd8d5.

PMID:
22179320
3.

Best paper NASS 2013: link-N can stimulate proteoglycan synthesis in the degenerated human intervertebral discs.

Gawri R, Antoniou J, Ouellet J, Awwad W, Steffen T, Roughley P, Haglund L, Mwale F.

Eur Cell Mater. 2013 Sep 11;26:107-19; discussion 119.

5.

Assessment of the matrix degenerative effects of MMP-3, ADAMTS-4, and HTRA1, injected into a bovine intervertebral disc organ culture model.

Furtwängler T, Chan SC, Bahrenberg G, Richards PJ, Gantenbein-Ritter B.

Spine (Phila Pa 1976). 2013 Oct 15;38(22):E1377-87. doi: 10.1097/BRS.0b013e31829ffde8.

6.

Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration.

Erwin WM, Islam D, Inman RD, Fehlings MG, Tsui FW.

Arthritis Res Ther. 2011;13(6):R215. doi: 10.1186/ar3548. Epub 2011 Dec 29.

7.

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration.

Le Maitre CL, Freemont AJ, Hoyland JA.

Arthritis Res Ther. 2005;7(4):R732-45. Epub 2005 Apr 1.

8.

MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc.

Gu SX, Li X, Hamilton JL, Chee A, Kc R, Chen D, An HS, Kim JS, Oh CD, Ma YZ, van Wijnen AJ, Im HJ.

Gene. 2015 Jan 25;555(2):80-7. doi: 10.1016/j.gene.2014.10.024. Epub 2014 Oct 12.

9.

Expression of proteinase-activated receptor-2 in the intervertebral disc.

Iida R, Akeda K, Kasai Y, Masuda K, Morimoto R, Sakakibara T, Sato M, Uchida A.

Spine (Phila Pa 1976). 2009 Mar 1;34(5):470-8. doi: 10.1097/BRS.0b013e318195a67d.

PMID:
19247167
10.

The action of resveratrol, a phytoestrogen found in grapes, on the intervertebral disc.

Li X, Phillips FM, An HS, Ellman M, Thonar EJ, Wu W, Park D, Im HJ.

Spine (Phila Pa 1976). 2008 Nov 15;33(24):2586-95. doi: 10.1097/BRS.0b013e3181883883.

11.

Fluid-induced, shear stress-regulated extracellular matrix and matrix metalloproteinase genes expression on human annulus fibrosus cells.

Chou PH, Wang ST, Yen MH, Liu CL, Chang MC, Lee OK.

Stem Cell Res Ther. 2016 Feb 27;7:34. doi: 10.1186/s13287-016-0292-5.

12.
14.

Nerve growth factor promotes expression of novel genes in intervertebral disc cells that regulate tissue degradation: Laboratory investigation.

Kao TH, Peng YJ, Tsou HK, Salter DM, Lee HS.

J Neurosurg Spine. 2014 Oct;21(4):653-61. doi: 10.3171/2014.6.SPINE13756. Epub 2014 Jul 25.

PMID:
25062286
16.

Age-related expression of MCP-1 and MMP-3 in mouse intervertebral disc in relation to TWEAK and TNF-α stimulation.

Fujita K, Ando T, Ohba T, Wako M, Sato N, Nakamura Y, Ohnuma Y, Hara Y, Kato R, Nakao A, Haro H.

J Orthop Res. 2012 Apr;30(4):599-605. doi: 10.1002/jor.21560. Epub 2011 Sep 16.

18.

Differential regulation of matrix degrading enzymes in a TNFalpha-induced model of nucleus pulposus tissue degeneration.

Séguin CA, Bojarski M, Pilliar RM, Roughley PJ, Kandel RA.

Matrix Biol. 2006 Sep;25(7):409-18. Epub 2006 Aug 23.

PMID:
16934445
19.
20.

Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration.

Yurube T, Takada T, Suzuki T, Kakutani K, Maeno K, Doita M, Kurosaka M, Nishida K.

Arthritis Res Ther. 2012 Mar 6;14(2):R51. doi: 10.1186/ar3764.

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