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Items: 1 to 20 of 95

1.

In vitro toxicological characterization of perfluorinated carboxylic acids with different carbon chain lengths.

Buhrke T, Kibellus A, Lampen A.

Toxicol Lett. 2013 Apr 12;218(2):97-104. doi: 10.1016/j.toxlet.2013.01.025. Epub 2013 Feb 4.

PMID:
23391484
2.

Perfluorooctanoic acid (PFOA) affects distinct molecular signalling pathways in human primary hepatocytes.

Buhrke T, Krüger E, Pevny S, Rößler M, Bitter K, Lampen A.

Toxicology. 2015 Jul 3;333:53-62. doi: 10.1016/j.tox.2015.04.004. Epub 2015 Apr 11.

PMID:
25868421
4.

Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths.

Wolf CJ, Takacs ML, Schmid JE, Lau C, Abbott BD.

Toxicol Sci. 2008 Nov;106(1):162-71. doi: 10.1093/toxsci/kfn166. Epub 2008 Aug 18.

PMID:
18713766
5.
6.
7.

Perfluorooctanoic acid induces apoptosis through the p53-dependent mitochondrial pathway in human hepatic cells: a proteomic study.

Huang Q, Zhang J, Martin FL, Peng S, Tian M, Mu X, Shen H.

Toxicol Lett. 2013 Nov 25;223(2):211-20. doi: 10.1016/j.toxlet.2013.09.002. Epub 2013 Sep 12.

PMID:
24035753
8.

Perfluorooctanoic acid affects the activity of the hepatocyte nuclear factor 4 alpha (HNF4α).

Scharmach E, Buhrke T, Lichtenstein D, Lampen A.

Toxicol Lett. 2012 Jul 20;212(2):106-12. doi: 10.1016/j.toxlet.2012.05.007. Epub 2012 May 16.

PMID:
22609092
9.

Comparative hepatic effects of perfluorooctanoic acid and WY 14,643 in PPAR-alpha knockout and wild-type mice.

Wolf DC, Moore T, Abbott BD, Rosen MB, Das KP, Zehr RD, Lindstrom AB, Strynar MJ, Lau C.

Toxicol Pathol. 2008 Jun;36(4):632-9. doi: 10.1177/0192623308318216. Epub 2008 May 8.

PMID:
18467680
10.

Structure-dependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ.

Zhang L, Ren XM, Wan B, Guo LH.

Toxicol Appl Pharmacol. 2014 Sep 15;279(3):275-83. doi: 10.1016/j.taap.2014.06.020. Epub 2014 Jul 3.

PMID:
24998974
11.

Hepatic Mitochondrial Alteration in CD-1 Mice Associated with Prenatal Exposures to Low Doses of Perfluorooctanoic Acid (PFOA).

Quist EM, Filgo AJ, Cummings CA, Kissling GE, Hoenerhoff MJ, Fenton SE.

Toxicol Pathol. 2015 Jun;43(4):546-57. doi: 10.1177/0192623314551841. Epub 2014 Oct 16.

12.

Perfluorooctanoic Acid (PFOA)-induced Liver Lesions in Two Strains of Mice Following Developmental Exposures: PPARα Is Not Required.

Filgo AJ, Quist EM, Hoenerhoff MJ, Brix AE, Kissling GE, Fenton SE.

Toxicol Pathol. 2015 Jun;43(4):558-68. doi: 10.1177/0192623314558463. Epub 2014 Nov 14.

13.

Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha.

Abbott BD, Wolf CJ, Schmid JE, Das KP, Zehr RD, Helfant L, Nakayama S, Lindstrom AB, Strynar MJ, Lau C.

Toxicol Sci. 2007 Aug;98(2):571-81. Epub 2007 May 7.

PMID:
17488742
14.
15.

Impacts of two perfluorinated compounds (PFOS and PFOA) on human hepatoma cells: cytotoxicity but no genotoxicity?

Florentin A, Deblonde T, Diguio N, Hautemaniere A, Hartemann P.

Int J Hyg Environ Health. 2011 Nov;214(6):493-9. doi: 10.1016/j.ijheh.2011.05.010. Epub 2011 Jun 14.

PMID:
21676652
16.

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.

Albrecht PP, Torsell NE, Krishnan P, Ehresman DJ, Frame SR, Chang SC, Butenhoff JL, Kennedy GL, Gonzalez FJ, Peters JM.

Toxicol Sci. 2013 Feb;131(2):568-82. doi: 10.1093/toxsci/kfs318. Epub 2012 Nov 9.

PMID:
23143925
17.

Suppression of antigen-specific antibody responses in mice exposed to perfluorooctanoic acid: Role of PPARα and T- and B-cell targeting.

DeWitt JC, Williams WC, Creech NJ, Luebke RW.

J Immunotoxicol. 2016;13(1):38-45. doi: 10.3109/1547691X.2014.996682. Epub 2015 Jan 16.

PMID:
25594567
18.

Perfluorooctanoic acid effects on steroid hormone and growth factor levels mediate stimulation of peripubertal mammary gland development in C57BL/6 mice.

Zhao Y, Tan YS, Haslam SZ, Yang C.

Toxicol Sci. 2010 May;115(1):214-24. doi: 10.1093/toxsci/kfq030. Epub 2010 Jan 29.

19.

Immunotoxicity of perfluorooctanoic acid and perfluorooctane sulfonate and the role of peroxisome proliferator-activated receptor alpha.

DeWitt JC, Shnyra A, Badr MZ, Loveless SE, Hoban D, Frame SR, Cunard R, Anderson SE, Meade BJ, Peden-Adams MM, Luebke RW, Luster MI.

Crit Rev Toxicol. 2009;39(1):76-94. doi: 10.1080/10408440802209804 . Review.

PMID:
18802816
20.

Analysis of structure-cytotoxicity in vitro relationship (SAR) for perfluorinated carboxylic acids.

Kleszczyński K, Gardzielewski P, Mulkiewicz E, Stepnowski P, Składanowski AC.

Toxicol In Vitro. 2007 Sep;21(6):1206-11. Epub 2007 May 10.

PMID:
17572060

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