Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 142

1.

Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease.

Pan P, Vermelho AB, Capaci Rodrigues G, Scozzafava A, Tolvanen ME, Parkkila S, Capasso C, Supuran CT.

J Med Chem. 2013 Feb 28;56(4):1761-71. doi: 10.1021/jm4000616. Epub 2013 Feb 19.

PMID:
23391336
2.

A class of sulfonamides with strong inhibitory action against the α-carbonic anhydrase from Trypanosoma cruzi.

Güzel-Akdemir Ö, Akdemir A, Pan P, Vermelho AB, Parkkila S, Scozzafava A, Capasso C, Supuran CT.

J Med Chem. 2013 Jul 25;56(14):5773-81. doi: 10.1021/jm400418p. Epub 2013 Jul 10.

PMID:
23815159
3.

Inhibition of carbonic anhydrase from Trypanosoma cruzi for the management of Chagas disease: an underexplored therapeutic opportunity.

Supuran CT.

Future Med Chem. 2016;8(3):311-24. doi: 10.4155/fmc.15.185. Epub 2016 Feb 22. Review.

PMID:
26898220
4.

Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease.

Pan P, Vermelho AB, Scozzafava A, Parkkila S, Capasso C, Supuran CT.

Bioorg Med Chem. 2013 Aug 1;21(15):4472-6. doi: 10.1016/j.bmc.2013.05.058. Epub 2013 Jun 6.

PMID:
23790722
5.
6.

Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.

Nishimori I, Vullo D, Minakuchi T, Morimoto K, Onishi S, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett. 2006 Apr 15;16(8):2182-8. Epub 2006 Feb 3.

PMID:
16459077
7.

A new class of quinazoline-sulfonamides acting as efficient inhibitors against the α-carbonic anhydrase from Trypanosoma cruzi.

Alafeefy AM, Ceruso M, Al-Jaber NA, Parkkila S, Vermelho AB, Supuran CT.

J Enzyme Inhib Med Chem. 2015;30(4):581-5. doi: 10.3109/14756366.2014.956309. Epub 2014 Nov 6.

PMID:
25373503
8.

Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.

Saczewski F, Innocenti A, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Scozzafava A, Temperini C, Supuran CT.

Bioorg Med Chem. 2008 Apr 1;16(7):3933-40. doi: 10.1016/j.bmc.2008.01.034. Epub 2008 Jan 26.

PMID:
18242998
9.

Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis.

Syrjänen L, Vermelho AB, Rodrigues Ide A, Corte-Real S, Salonen T, Pan P, Vullo D, Parkkila S, Capasso C, Supuran CT.

J Med Chem. 2013 Sep 26;56(18):7372-81. doi: 10.1021/jm400939k. Epub 2013 Sep 13.

PMID:
23977960
10.

Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.

Vullo D, Voipio J, Innocenti A, Rivera C, Ranki H, Scozzafava A, Kaila K, Supuran CT.

Bioorg Med Chem Lett. 2005 Feb 15;15(4):971-6.

PMID:
15686895
11.

Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors.

Güzel O, Innocenti A, Scozzafava A, Salman A, Supuran CT.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3170-3. doi: 10.1016/j.bmcl.2009.04.123. Epub 2009 May 3.

PMID:
19435663
12.

Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.

Nishimori I, Minakuchi T, Morimoto K, Sano S, Onishi S, Takeuchi H, Vullo D, Scozzafava A, Supuran CT.

J Med Chem. 2006 Mar 23;49(6):2117-26.

PMID:
16539401
13.

Amide derivatives with pyrazole carboxylic acids of 5-amino-1,3,4-thiadiazole 2-sulfonamide as new carbonic anhydrase inhibitors: synthesis and investigation of inhibitory effects.

Bülbül M, Kasimoğullari R, Küfrevioğlu OI.

J Enzyme Inhib Med Chem. 2008 Dec;23(6):895-900. doi: 10.1080/14756360701626173 .

PMID:
18618324
14.

Design, synthesis, and evaluation of hydroxamic acid derivatives as promising agents for the management of Chagas disease.

Rodrigues GC, Feijó DF, Bozza MT, Pan P, Vullo D, Parkkila S, Supuran CT, Capasso C, Aguiar AP, Vermelho AB.

J Med Chem. 2014 Jan 23;57(2):298-308. doi: 10.1021/jm400902y. Epub 2013 Dec 13.

PMID:
24299463
15.

Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.

Güzel O, Innocenti A, Scozzafava A, Salman A, Supuran CT.

Bioorg Med Chem. 2009 Jul 15;17(14):4894-9. doi: 10.1016/j.bmc.2009.06.006. Epub 2009 Jun 9.

PMID:
19539481
16.

Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.

Vullo D, De Luca V, Del Prete S, Carginale V, Scozzafava A, Capasso C, Supuran CT.

Bioorg Med Chem Lett. 2015 Sep 1;25(17):3550-5. doi: 10.1016/j.bmcl.2015.06.079. Epub 2015 Jul 3.

PMID:
26174556
19.
20.

Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.

Nishimori I, Vullo D, Minakuchi T, Scozzafava A, Capasso C, Supuran CT.

Bioorg Med Chem. 2014 Jun 1;22(11):2939-46. doi: 10.1016/j.bmc.2014.04.006. Epub 2014 Apr 13.

PMID:
24792813

Supplemental Content

Support Center