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A yeast telomerase complex containing the Est1 recruitment protein is assembled early in the cell cycle.

Tucey TM, Lundblad V.

Biochemistry. 2013 Feb 19;52(7):1131-3. doi: 10.1021/bi3015218. Epub 2013 Feb 7. Erratum in: Biochemistry. 2013 Jul 23;52(29):5027.


The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro.

Wu Y, Zakian VA.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20362-9. doi: 10.1073/pnas.1100281108. Epub 2011 Oct 3.


The mechanisms of K. lactis Cdc13 in telomere DNA-binding and telomerase regulation.

Hsu M, Lue NF.

DNA Repair (Amst). 2018 Jan;61:37-45. doi: 10.1016/j.dnarep.2017.11.007. Epub 2017 Nov 28.


Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.

Li S, Makovets S, Matsuguchi T, Blethrow JD, Shokat KM, Blackburn EH.

Cell. 2009 Jan 9;136(1):50-61. doi: 10.1016/j.cell.2008.11.027.


Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication.

Liu CC, Gopalakrishnan V, Poon LF, Yan T, Li S.

Mol Cell Biol. 2014 Jan;34(1):57-70. doi: 10.1128/MCB.01235-13. Epub 2013 Oct 28.


Structural Insights into Yeast Telomerase Recruitment to Telomeres.

Chen H, Xue J, Churikov D, Hass EP, Shi S, Lemon LD, Luciano P, Bertuch AA, Zappulla DC, Géli V, Wu J, Lei M.

Cell. 2018 Jan 11;172(1-2):331-343.e13. doi: 10.1016/j.cell.2017.12.008. Epub 2017 Dec 28.


Est1 and Cdc13 as comediators of telomerase access.

Evans SK, Lundblad V.

Science. 1999 Oct 1;286(5437):117-20.


Cdc13 and telomerase bind through different mechanisms at the lagging- and leading-strand telomeres.

Faure V, Coulon S, Hardy J, Géli V.

Mol Cell. 2010 Jun 25;38(6):842-52. doi: 10.1016/j.molcel.2010.05.016.


Est1 protects telomeres and inhibits subtelomeric y'-element recombination.

Tong XJ, Li QJ, Duan YM, Liu NN, Zhang ML, Zhou JQ.

Mol Cell Biol. 2011 Mar;31(6):1263-74. doi: 10.1128/MCB.00831-10. Epub 2011 Jan 10.


Sequential phosphorylation of CST subunits by different cyclin-Cdk1 complexes orchestrate telomere replication.

Gopalakrishnan V, Tan CR, Li S.

Cell Cycle. 2017 Jul 3;16(13):1271-1287. doi: 10.1080/15384101.2017.1312235. Epub 2017 Jun 26.


Telomerase recruitment in Saccharomyces cerevisiae is not dependent on Tel1-mediated phosphorylation of Cdc13.

Gao H, Toro TB, Paschini M, Braunstein-Ballew B, Cervantes RB, Lundblad V.

Genetics. 2010 Dec;186(4):1147-59. doi: 10.1534/genetics.110.122044. Epub 2010 Sep 13.


Est1p as a cell cycle-regulated activator of telomere-bound telomerase.

Taggart AK, Teng SC, Zakian VA.

Science. 2002 Aug 9;297(5583):1023-6.


The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres.

Williams JM, Ouenzar F, Lemon LD, Chartrand P, Bertuch AA.

Genetics. 2014 Aug;197(4):1123-36. doi: 10.1534/genetics.114.164707. Epub 2014 May 30.


The Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitro.

Tuzon CT, Wu Y, Chan A, Zakian VA.

PLoS Genet. 2011 May;7(5):e1002060. doi: 10.1371/journal.pgen.1002060. Epub 2011 May 5.


Fine tuning the level of the Cdc13 telomere-capping protein for maximal chromosome stability performance.

Mersaoui SY, Wellinger RJ.

Curr Genet. 2019 Feb;65(1):109-118. doi: 10.1007/s00294-018-0871-3. Epub 2018 Jul 31. Review.


Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition.

Puglisi A, Bianchi A, Lemmens L, Damay P, Shore D.

EMBO J. 2008 Sep 3;27(17):2328-39. doi: 10.1038/emboj.2008.158.


SUMOylation regulates telomere length homeostasis by targeting Cdc13.

Hang LE, Liu X, Cheung I, Yang Y, Zhao X.

Nat Struct Mol Biol. 2011 Jul 10;18(8):920-6. doi: 10.1038/nsmb.2100.


The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis.

Sealey DC, Kostic AD, LeBel C, Pryde F, Harrington L.

BMC Mol Biol. 2011 Oct 18;12:45. doi: 10.1186/1471-2199-12-45.

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