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Items: 1 to 20 of 132

1.

Regulatory T cells migrate to airways via CCR4 and attenuate the severity of airway allergic inflammation.

Faustino L, da Fonseca DM, Takenaka MC, Mirotti L, Florsheim EB, Guereschi MG, Silva JS, Basso AS, Russo M.

J Immunol. 2013 Mar 15;190(6):2614-21. doi: 10.4049/jimmunol.1202354. Epub 2013 Feb 6.

2.

Differential regulatory function of resting and preactivated allergen-specific CD4+ CD25+ regulatory T cells in Th2-type airway inflammation.

Saito K, Torii M, Ma N, Tsuchiya T, Wang L, Hori T, Nagakubo D, Nitta N, Kanegasaki S, Hieshima K, Yoshie O, Gabazza EC, Katayama N, Shiku H, Kuribayashi K, Kato T.

J Immunol. 2008 Nov 15;181(10):6889-97.

3.

Selective down-regulation of Th2 cell-mediated airway inflammation in mice by pharmacological intervention of CCR4.

Kaminuma O, Ohtomo T, Mori A, Nagakubo D, Hieshima K, Ohmachi Y, Noda Y, Katayama K, Suzuki K, Motoi Y, Kitamura N, Saeki M, Nishimura T, Yoshie O, Hiroi T.

Clin Exp Allergy. 2012 Feb;42(2):315-25. doi: 10.1111/j.1365-2222.2011.03847.x. Epub 2011 Sep 1.

PMID:
22092376
4.

Regulatory T cells accumulate in the lung allergic inflammation and efficiently suppress T-cell proliferation but not Th2 cytokine production.

Faustino L, Mucida D, Keller AC, Demengeot J, Bortoluci K, Sardinha LR, Carla Takenaka M, Basso AS, Faria AM, Russo M.

Clin Dev Immunol. 2012;2012:721817. doi: 10.1155/2012/721817. Epub 2011 Nov 15.

5.

Inhibitory effect of the new orally active CCR4 antagonist K327 on CCR4+CD4+ T cell migration into the lung of mice with ovalbumin-induced lung allergic inflammation.

Sato T, Komai M, Iwase M, Kobayashi K, Tahara H, Ohshima E, Arai H, Miki I.

Pharmacology. 2009;84(3):171-82. doi: 10.1159/000235748. Epub 2009 Aug 27.

PMID:
19713720
6.

Contribution of CCR4 and CCR8 to antigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation.

Mikhak Z, Fukui M, Farsidjani A, Medoff BD, Tager AM, Luster AD.

J Allergy Clin Immunol. 2009 Jan;123(1):67-73.e3. doi: 10.1016/j.jaci.2008.09.049. Epub 2008 Dec 4.

7.

Compartmentalized chemokine-dependent regulatory T-cell inhibition of allergic pulmonary inflammation.

Afshar R, Strassner JP, Seung E, Causton B, Cho JL, Harris RS, Hamilos DL, Medoff BD, Luster AD.

J Allergy Clin Immunol. 2013 Jun;131(6):1644-52. doi: 10.1016/j.jaci.2013.03.002. Epub 2013 Apr 28.

8.

MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung.

Malmhäll C, Alawieh S, Lu Y, Sjöstrand M, Bossios A, Eldh M, Rådinger M.

J Allergy Clin Immunol. 2014 May;133(5):1429-38, 1438.e1-7. doi: 10.1016/j.jaci.2013.11.008. Epub 2013 Dec 24.

PMID:
24373357
9.

High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism.

Nakagome K, Imamura M, Kawahata K, Harada H, Okunishi K, Matsumoto T, Sasaki O, Tanaka R, Kano MR, Chang H, Hanawa H, Miyazaki J, Yamamoto K, Dohi M.

J Immunol. 2011 Nov 15;187(10):5077-89. doi: 10.4049/jimmunol.1001560. Epub 2011 Oct 12.

10.

Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis.

Gonzalo JA, Qiu Y, Lora JM, Al-Garawi A, Villeval JL, Boyce JA, Martinez-A C, Marquez G, Goya I, Hamid Q, Fraser CC, Picarella D, Cote-Sierra J, Hodge MR, Gutierrez-Ramos JC, Kolbeck R, Coyle AJ.

J Immunol. 2007 Aug 1;179(3):1740-50.

12.

Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patients.

Vijayanand P, Durkin K, Hartmann G, Morjaria J, Seumois G, Staples KJ, Hall D, Bessant C, Bartholomew M, Howarth PH, Friedmann PS, Djukanovic R.

J Immunol. 2010 Apr 15;184(8):4568-74. doi: 10.4049/jimmunol.0901342. Epub 2010 Mar 17.

13.

Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice.

Seto Y, Nakajima H, Suto A, Shimoda K, Saito Y, Nakayama KI, Iwamoto I.

J Immunol. 2003 Jan 15;170(2):1077-83.

14.

CD4+CD25+ T cells regulate airway eosinophilic inflammation by modulating the Th2 cell phenotype.

Jaffar Z, Sivakuru T, Roberts K.

J Immunol. 2004 Mar 15;172(6):3842-9.

15.

Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN-gamma-dependent mechanism.

Tang C, Inman MD, van Rooijen N, Yang P, Shen H, Matsumoto K, O'Byrne PM.

J Immunol. 2001 Feb 1;166(3):1471-81.

16.

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice.

Miyazaki Y, Inoue H, Matsumura M, Matsumoto K, Nakano T, Tsuda M, Hamano S, Yoshimura A, Yoshida H.

J Immunol. 2005 Aug 15;175(4):2401-7.

17.

Resolution of Der p1-induced allergic airway inflammation is dependent on CD4+CD25+Foxp3+ regulatory cells.

Leech MD, Benson RA, De Vries A, Fitch PM, Howie SE.

J Immunol. 2007 Nov 15;179(10):7050-8.

18.

Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation.

Perros F, Hoogsteden HC, Coyle AJ, Lambrecht BN, Hammad H.

Allergy. 2009 Jul;64(7):995-1002. doi: 10.1111/j.1398-9995.2009.02095.x.

19.

CD4-mediated regulatory T-cell activation inhibits the development of disease in a humanized mouse model of allergic airway disease.

Martin H, Reuter S, Dehzad N, Heinz A, Bellinghausen I, Saloga J, Haasler I, Korn S, Jonuleit H, Buhl R, Becker C, Taube C.

J Allergy Clin Immunol. 2012 Feb;129(2):521-8, 528.e1-7. doi: 10.1016/j.jaci.2011.09.038. Epub 2011 Nov 10.

PMID:
22078574
20.

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

Katoh S, Oomizu S, Niki T, Shimizu H, Obase Y, Korenaga M, Oka M, Hirashima M.

Int Arch Allergy Immunol. 2012;158 Suppl 1:58-65. doi: 10.1159/000337769. Epub 2012 May 15.

PMID:
22627368

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