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Items: 1 to 20 of 302

1.

Modulation of Nrf2/Keap1 system by Wasabi 6-methylthiohexyl isothiocyanate in ARE-mediated NQO1 expression.

Korenori Y, Tanigawa S, Kumamoto T, Qin S, Daikoku Y, Miyamori K, Nagai M, Hou DX.

Mol Nutr Food Res. 2013 May;57(5):854-64. doi: 10.1002/mnfr.201200689. Epub 2013 Feb 6.

PMID:
23390006
2.

Dynamics of Nrf2 and Keap1 in ARE-mediated NQO1 expression by wasabi 6-(methylsulfinyl)hexyl isothiocyanate.

Hou DX, Korenori Y, Tanigawa S, Yamada-Kato T, Nagai M, He X, He J.

J Agric Food Chem. 2011 Nov 23;59(22):11975-82. doi: 10.1021/jf2032439. Epub 2011 Nov 1.

PMID:
22010800
3.

Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin.

Tanigawa S, Fujii M, Hou DX.

Free Radic Biol Med. 2007 Jun 1;42(11):1690-703. Epub 2007 Feb 28.

PMID:
17462537
4.

Baicalein modulates Nrf2/Keap1 system in both Keap1-dependent and Keap1-independent mechanisms.

Qin S, Deng F, Wu W, Jiang L, Yamashiro T, Yano S, Hou DX.

Arch Biochem Biophys. 2014 Oct 1;559:53-61. doi: 10.1016/j.abb.2014.03.011. Epub 2014 Apr 3.

PMID:
24704364
6.

The Nrf2-Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO).

Rinaldi Tosi ME, Bocanegra V, Manucha W, Gil Lorenzo A, Vallés PG.

Cell Stress Chaperones. 2011 Jan;16(1):57-68. doi: 10.1007/s12192-010-0221-y. Epub 2010 Aug 24.

7.

NAD(P)H:quinone oxidoreductase 1 activity reduces hypertrophy in 3T3-L1 adipocytes.

Vomhof-DeKrey EE, Picklo MJ.

Free Radic Biol Med. 2012 Aug 15;53(4):690-700. doi: 10.1016/j.freeradbiomed.2012.05.047. Epub 2012 Jun 8.

PMID:
22683604
8.

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

Anwar-Mohamed A, Elshenawy OH, Soshilov AA, Denison MS, Chris Le X, Klotz LO, El-Kadi AO.

Free Radic Biol Med. 2014 Feb;67:171-87. doi: 10.1016/j.freeradbiomed.2013.10.810. Epub 2013 Oct 24.

PMID:
24161444
9.

Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.

Ohnuma T, Nakayama S, Anan E, Nishiyama T, Ogura K, Hiratsuka A.

Toxicol Appl Pharmacol. 2010 Apr 1;244(1):27-36. doi: 10.1016/j.taap.2009.12.012. Epub 2009 Dec 21.

PMID:
20026152
10.

Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells.

Li CQ, Kim MY, Godoy LC, Thiantanawat A, Trudel LJ, Wogan GN.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14547-51. doi: 10.1073/pnas.0907539106. Epub 2009 Aug 11.

11.

Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.

Zhan L, Zhang H, Zhang Q, Woods CG, Chen Y, Xue P, Dong J, Tokar EJ, Xu Y, Hou Y, Fu J, Yarborough K, Wang A, Qu W, Waalkes MP, Andersen ME, Pi J.

Free Radic Biol Med. 2012 Aug 15;53(4):758-68. doi: 10.1016/j.freeradbiomed.2012.05.041. Epub 2012 Jun 7.

12.

Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system.

Pang C, Zheng Z, Shi L, Sheng Y, Wei H, Wang Z, Ji L.

Free Radic Biol Med. 2016 Feb;91:236-46. doi: 10.1016/j.freeradbiomed.2015.12.024. Epub 2015 Dec 23.

PMID:
26721592
13.

Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2.

Chen YT, Shi D, Yang D, Yan B.

Biochem Pharmacol. 2012 Sep 15;84(6):864-71. doi: 10.1016/j.bcp.2012.06.025. Epub 2012 Jul 6.

14.

A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways.

Gan FF, Ling H, Ang X, Reddy SA, Lee SS, Yang H, Tan SH, Hayes JD, Chui WK, Chew EH.

Toxicol Appl Pharmacol. 2013 Nov 1;272(3):852-62. doi: 10.1016/j.taap.2013.07.011. Epub 2013 Jul 27.

PMID:
23899529
15.

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.

Ungvari Z, Bagi Z, Feher A, Recchia FA, Sonntag WE, Pearson K, de Cabo R, Csiszar A.

Am J Physiol Heart Circ Physiol. 2010 Jul;299(1):H18-24. doi: 10.1152/ajpheart.00260.2010. Epub 2010 Apr 23.

16.

Extract of Ginkgo biloba induces phase 2 genes through Keap1-Nrf2-ARE signaling pathway.

Liu XP, Goldring CE, Copple IM, Wang HY, Wei W, Kitteringham NR, Park BK.

Life Sci. 2007 Apr 3;80(17):1586-91. Epub 2007 Jan 27.

PMID:
17316704
17.

HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway.

Ade N, Leon F, Pallardy M, Peiffer JL, Kerdine-Romer S, Tissier MH, Bonnet PA, Fabre I, Ourlin JC.

Toxicol Sci. 2009 Feb;107(2):451-60. doi: 10.1093/toxsci/kfn243. Epub 2008 Nov 25.

PMID:
19033392
18.

Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling.

Li L, Dong H, Song E, Xu X, Liu L, Song Y.

Chem Biol Interact. 2014 Feb 25;209:56-67. doi: 10.1016/j.cbi.2013.12.005. Epub 2013 Dec 17.

PMID:
24361488
19.

Cytoprotection against beta-amyloid (Aβ) peptide-mediated oxidative damage and autophagy by Keap1 RNAi in human glioma U87mg cells.

Youn P, Chen Y, Furgeson DY.

Neurosci Res. 2015 May;94:70-8. doi: 10.1016/j.neures.2014.12.015. Epub 2015 Jan 20.

PMID:
25612817
20.

Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.

Su C, Zhang P, Song X, Shi Q, Fu J, Xia X, Bai H, Hu L, Xu D, Song E, Song Y.

Chem Res Toxicol. 2015 Apr 20;28(4):765-74. doi: 10.1021/tx500513v. Epub 2015 Mar 11.

PMID:
25742418

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