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Items: 1 to 20 of 199

1.

Protein kinase Cα inhibitor protects against downregulation of claudin-1 during epithelial-mesenchymal transition of pancreatic cancer.

Kyuno D, Kojima T, Yamaguchi H, Ito T, Kimura Y, Imamura M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N.

Carcinogenesis. 2013 Jun;34(6):1232-43. doi: 10.1093/carcin/bgt057. Epub 2013 Feb 6.

PMID:
23389293
2.

Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells.

Kojima T, Takasawa A, Kyuno D, Ito T, Yamaguchi H, Hirata K, Tsujiwaki M, Murata M, Tanaka S, Sawada N.

Exp Cell Res. 2011 Oct 1;317(16):2288-98. doi: 10.1016/j.yexcr.2011.06.020. Epub 2011 Jul 8.

PMID:
21763689
3.

Protein kinase Cα inhibitor enhances the sensitivity of human pancreatic cancer HPAC cells to Clostridium perfringens enterotoxin via claudin-4.

Kyuno D, Kojima T, Ito T, Yamaguchi H, Tsujiwaki M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N.

Cell Tissue Res. 2011 Dec;346(3):369-81. doi: 10.1007/s00441-011-1287-2. Epub 2011 Dec 13.

PMID:
22160590
4.

Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition.

Ouelaa-Benslama R, De Wever O, Hendrix A, Sabbah M, Lambein K, Land D, Prévost G, Bracke M, Hung MC, Larsen AK, Emami S, Gespach C.

Int J Oncol. 2012 Jul;41(1):189-200. doi: 10.3892/ijo.2012.1457. Epub 2012 Apr 30.

PMID:
22552300
5.

Epidermal growth factor promotes transforming growth factor-β1-induced epithelial-mesenchymal transition in HK-2 cells through a synergistic effect on Snail.

Xiong J, Sun Q, Ji K, Wang Y, Liu H.

Mol Biol Rep. 2014 Jan;41(1):241-50. doi: 10.1007/s11033-013-2857-z. Epub 2013 Nov 8.

PMID:
24203464
6.

A novel molecular pathway for Snail-dependent, SPARC-mediated invasion in non-small cell lung cancer pathogenesis.

Grant JL, Fishbein MC, Hong LS, Krysan K, Minna JD, Shay JW, Walser TC, Dubinett SM.

Cancer Prev Res (Phila). 2014 Jan;7(1):150-60. doi: 10.1158/1940-6207.CAPR-13-0263. Epub 2013 Nov 19.

7.

Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells.

Kojima T, Sawada N.

Ann N Y Acad Sci. 2012 Jun;1257:85-92. doi: 10.1111/j.1749-6632.2012.06579.x.

PMID:
22671593
8.

Snail involves in the transforming growth factor β1-mediated epithelial-mesenchymal transition of retinal pigment epithelial cells.

Li H, Wang H, Wang F, Gu Q, Xu X.

PLoS One. 2011;6(8):e23322. doi: 10.1371/journal.pone.0023322. Epub 2011 Aug 10.

9.

Protein kinase Cα mediates erlotinib resistance in lung cancer cells.

Abera MB, Kazanietz MG.

Mol Pharmacol. 2015 May;87(5):832-41. doi: 10.1124/mol.115.097725. Epub 2015 Feb 27.

10.

Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells.

Yamaguchi H, Kojima T, Ito T, Kimura Y, Imamura M, Son S, Koizumi J, Murata M, Nagayama M, Nobuoka T, Tanaka S, Hirata K, Sawada N.

Am J Pathol. 2010 Aug;177(2):698-712. doi: 10.2353/ajpath.2010.091226. Epub 2010 Jun 21.

11.

SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo.

Nishioka R, Itoh S, Gui T, Gai Z, Oikawa K, Kawai M, Tani M, Yamaue H, Muragaki Y.

Exp Mol Pathol. 2010 Oct;89(2):149-57. doi: 10.1016/j.yexmp.2010.05.008. Epub 2010 Jun 1.

PMID:
20576520
12.

Egr-1 mediates chronic hypoxia-induced renal interstitial fibrosis via the PKC/ERK pathway.

Sun S, Ning X, Zhai Y, Du R, Lu Y, He L, Li R, Wu W, Sun W, Wang H.

Am J Nephrol. 2014;39(5):436-48. doi: 10.1159/000362249. Epub 2014 May 10.

PMID:
24819335
13.

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes.

Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, Mani SA.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15449-54. doi: 10.1073/pnas.1004900107. Epub 2010 Aug 16. Erratum in: Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19132.

14.

The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer.

Wu Y, Sato F, Yamada T, Bhawal UK, Kawamoto T, Fujimoto K, Noshiro M, Seino H, Morohashi S, Hakamada K, Abiko Y, Kato Y, Kijima H.

Int J Oncol. 2012 Oct;41(4):1337-46. doi: 10.3892/ijo.2012.1559. Epub 2012 Jul 18.

PMID:
22825629
15.

Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes.

Kojima T, Takano K, Yamamoto T, Murata M, Son S, Imamura M, Yamaguchi H, Osanai M, Chiba H, Himi T, Sawada N.

Liver Int. 2008 Apr;28(4):534-45. Epub 2007 Nov 21.

PMID:
18031476
16.

TGF-β and EGF induced HLA-I downregulation is associated with epithelial-mesenchymal transition (EMT) through upregulation of snail in prostate cancer cells.

Chen XH, Liu ZC, Zhang G, Wei W, Wang XX, Wang H, Ke HP, Zhang F, Wang HS, Cai SH, Du J.

Mol Immunol. 2015 May;65(1):34-42. doi: 10.1016/j.molimm.2014.12.017. Epub 2015 Jan 22.

PMID:
25618241
18.

Over-expression of lipocalin 2 promotes cell migration and invasion through activating ERK signaling to increase SLUG expression in prostate cancer.

Ding G, Fang J, Tong S, Qu L, Jiang H, Ding Q, Liu J.

Prostate. 2015 Jun 15;75(9):957-68. doi: 10.1002/pros.22978. Epub 2015 Feb 25.

PMID:
25728945
19.
20.

Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells.

Ito T, Kojima T, Yamaguchi H, Kyuno D, Kimura Y, Imamura M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N.

J Cell Biochem. 2011 Jul;112(7):1761-72. doi: 10.1002/jcb.23095.

PMID:
21381080

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