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Items: 1 to 20 of 96

1.

Conjugates of modified cryptophycins and RGD-peptides enter target cells by endocytosis.

Nahrwold M, Weiß C, Bogner T, Mertink F, Conradi J, Sammet B, Palmisano R, Royo Gracia S, Preuße T, Sewald N.

J Med Chem. 2013 Mar 14;56(5):1853-64. doi: 10.1021/jm301346z. Epub 2013 Feb 22.

PMID:
23387527
2.

Recent approaches for the synthesis of modified cryptophycins.

Weiss C, Sammet B, Sewald N.

Nat Prod Rep. 2013 Jul;30(7):924-40. doi: 10.1039/c3np70022d. Review.

PMID:
23732943
3.

Efficient synthesis of cryptophycin-52 and novel para-alkoxymethyl unit A analogues.

Eissler S, Bogner T, Nahrwold M, Sewald N.

Chemistry. 2009 Oct 26;15(42):11273-87. doi: 10.1002/chem.200901750.

PMID:
19760734
4.

Approaches for the synthesis of functionalized cryptophycins.

Sammet B, Bogner T, Nahrwold M, Weiss C, Sewald N.

J Org Chem. 2010 Oct 15;75(20):6953-60. doi: 10.1021/jo101563s.

PMID:
20857920
5.

Cryptophycins: a novel class of potent antimitotic antitumor depsipeptides.

Shih C, Teicher BA.

Curr Pharm Des. 2001 Sep;7(13):1259-76. Review.

PMID:
11472266
6.

Three new cryptophycins from Nostoc sp. GSV 224.

Subbaraju GV, Golakoti T, Patterson GM, Moore RE.

J Nat Prod. 1997 Mar;60(3):302-5.

PMID:
9090872
7.

Efficient and versatile stereoselective synthesis of cryptophycins.

Mast CA, Eissler S, Stoncius A, Stammler HG, Neumann B, Sewald N.

Chemistry. 2005 Aug 5;11(16):4667-77.

PMID:
15915529
8.

Isolation and structure determination of cryptophycins 38, 326, and 327 from the terrestrial cyanobacterium Nostoc sp. GSV 224.

Chaganty S, Golakoti T, Heltzel C, Moore RE, Yoshida WY.

J Nat Prod. 2004 Aug;67(8):1403-6.

PMID:
15332864
9.

Localization of the antimitotic peptide and depsipeptide binding site on beta-tubulin.

Mitra A, Sept D.

Biochemistry. 2004 Nov 9;43(44):13955-62.

PMID:
15518544
10.

Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging.

Mickler FM, Vachutinsky Y, Oba M, Miyata K, Nishiyama N, Kataoka K, Bräuchle C, Ruthardt N.

J Control Release. 2011 Dec 20;156(3):364-73. doi: 10.1016/j.jconrel.2011.08.003. Epub 2011 Aug 6.

PMID:
21843561
11.

Total synthesis and anti-tubulin activity of epi-c3 analogues of cryptophycin-24.

Buck SB, Huff JK, Himes RH, Georg GI.

J Med Chem. 2004 Jul 1;47(14):3697-9.

PMID:
15214797
12.

Cryptophycins-309, 249 and other cryptophycin analogs: preclinical efficacy studies with mouse and human tumors.

Liang J, Moore RE, Moher ED, Munroe JE, Al-awar RS, Hay DA, Varie DL, Zhang TY, Aikins JA, Martinelli MJ, Shih C, Ray JE, Gibson LL, Vasudevan V, Polin L, White K, Kushner J, Simpson C, Pugh S, Corbett TH.

Invest New Drugs. 2005 Jun;23(3):213-24.

PMID:
15868377
13.

Total synthesis and biological evaluation of fluorinated cryptophycins.

Weiß C, Bogner T, Sammet B, Sewald N.

Beilstein J Org Chem. 2012;8:2060-6. doi: 10.3762/bjoc.8.231. Epub 2012 Nov 23.

14.

Design and synthesis of a new class of cryptophycins based tubulin inhibitors.

Kumar A, Kumar M, Sharma S, Guru SK, Bhushan S, Shah BA.

Eur J Med Chem. 2015 Mar 26;93:55-63. doi: 10.1016/j.ejmech.2014.11.068. Epub 2015 Jan 28.

PMID:
25647428
15.

Total synthesis of cryptophycin analogues via a scaffold approach.

McCubbin JA, Maddess ML, Lautens M.

Org Lett. 2006 Jul 6;8(14):2993-6.

PMID:
16805535
16.

Cryptophycins: cytotoxic cyclodepsipeptides with potential for tumor targeting.

Weiss C, Figueras E, Borbely AN, Sewald N.

J Pept Sci. 2017 Jun 29. doi: 10.1002/psc.3015. [Epub ahead of print]

PMID:
28661555
17.

Biological evaluation of cryptophycin 52 fragment A analogues: effect of the multidrug resistance ATP binding cassette transporters on antitumor activity.

Al-Awar RS, Corbett TH, Ray JE, Polin L, Kennedy JH, Wagner MM, Williams DC.

Mol Cancer Ther. 2004 Sep;3(9):1061-7.

18.

Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates.

Sutherland MS, Sanderson RJ, Gordon KA, Andreyka J, Cerveny CG, Yu C, Lewis TS, Meyer DL, Zabinski RF, Doronina SO, Senter PD, Law CL, Wahl AF.

J Biol Chem. 2006 Apr 14;281(15):10540-7. Epub 2006 Feb 16.

19.

Water-soluble polymers for targeted drug delivery to human squamous carcinoma of head and neck.

Nan A, Ghandehari H, Hebert C, Siavash H, Nikitakis N, Reynolds M, Sauk JJ.

J Drug Target. 2005 Apr;13(3):189-97.

PMID:
16036307
20.

Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts.

Magarvey NA, Beck ZQ, Golakoti T, Ding Y, Huber U, Hemscheidt TK, Abelson D, Moore RE, Sherman DH.

ACS Chem Biol. 2006 Dec 15;1(12):766-79.

PMID:
17240975

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