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Items: 1 to 20 of 148

1.

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox.

Cordova FM, Aguiar AS Jr, Peres TV, Lopes MW, Gonçalves FM, Pedro DZ, Lopes SC, Pilati C, Prediger RD, Farina M, Erikson KM, Aschner M, Leal RB.

Arch Toxicol. 2013 Jul;87(7):1231-44. doi: 10.1007/s00204-013-1017-5. Epub 2013 Feb 6.

PMID:
23385959
2.

In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function.

Cordova FM, Aguiar AS Jr, Peres TV, Lopes MW, Gonçalves FM, Remor AP, Lopes SC, Pilati C, Latini AS, Prediger RD, Erikson KM, Aschner M, Leal RB.

PLoS One. 2012;7(3):e33057. doi: 10.1371/journal.pone.0033057. Epub 2012 Mar 13.

3.

A possible neuroprotective action of a vinylic telluride against Mn-induced neurotoxicity.

Avila DS, Colle D, Gubert P, Palma AS, Puntel G, Manarin F, Noremberg S, Nascimento PC, Aschner M, Rocha JB, Soares FA.

Toxicol Sci. 2010 May;115(1):194-201. doi: 10.1093/toxsci/kfq036. Epub 2010 Feb 4.

4.

Protection by Edaravone, a Radical Scavenger, against Manganese-Induced Neurotoxicity in Rats.

Apaydin M, Erbas O, Taskiran D.

J Biochem Mol Toxicol. 2016 May;30(5):217-23. doi: 10.1002/jbt.21780. Epub 2016 Jan 18.

PMID:
26778341
5.

Short-term manganese inhalation decreases brain dopamine transporter levels without disrupting motor skills in rats.

Saputra D, Chang J, Lee BJ, Yoon JH, Kim J, Lee K.

J Toxicol Sci. 2016;41(3):391-402. doi: 10.2131/jts.41.391.

6.

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity.

Milatovic D, Zaja-Milatovic S, Gupta RC, Yu Y, Aschner M.

Toxicol Appl Pharmacol. 2009 Oct 15;240(2):219-25. doi: 10.1016/j.taap.2009.07.004. Epub 2009 Jul 14.

7.

Involvement of striatal lipid peroxidation and inhibition of calcium influx into brain slices in neurobehavioral alterations in a rat model of short-term oral exposure to manganese.

Avila DS, Gubert P, Fachinetto R, Wagner C, Aschner M, Rocha JB, Soares FA.

Neurotoxicology. 2008 Nov;29(6):1062-8. doi: 10.1016/j.neuro.2008.08.004. Epub 2008 Aug 20.

PMID:
18778733
8.

Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine.

Garcia E, Limon D, Perez-De La Cruz V, Giordano M, Diaz-Muñoz M, Maldonado PD, Herrera-Mundo MN, Pedraza-Chaverri J, Santamaria A.

Free Radic Res. 2008 Oct;42(10):892-902. doi: 10.1080/10715760802506356. Erratum in: Free Radic Res. 2009 Feb;43(2):193.

PMID:
18985488
9.

Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury.

Milatovic D, Gupta RC, Yu Y, Zaja-Milatovic S, Aschner M.

Toxicol Appl Pharmacol. 2011 Nov 1;256(3):219-26. doi: 10.1016/j.taap.2011.06.001. Epub 2011 Jun 13.

10.

Developmental exposure to manganese induces lasting motor and cognitive impairment in rats.

Peres TV, Eyng H, Lopes SC, Colle D, Gonçalves FM, Venske DK, Lopes MW, Ben J, Bornhorst J, Schwerdtle T, Aschner M, Farina M, Prediger RD, Leal RB.

Neurotoxicology. 2015 Sep;50:28-37. doi: 10.1016/j.neuro.2015.07.005. Epub 2015 Jul 26.

PMID:
26215118
11.
12.

α-Synuclein overexpression enhances manganese-induced neurotoxicity through the NF-κB-mediated pathway.

Prabhakaran K, Chapman GD, Gunasekar PG.

Toxicol Mech Methods. 2011 Jul;21(6):435-43. doi: 10.3109/15376516.2011.560210. Epub 2011 Mar 21.

PMID:
21417633
13.

Manganese-induced oxidative DNA damage in neuronal SH-SY5Y cells: attenuation of thymine base lesions by glutathione and N-acetylcysteine.

Stephenson AP, Schneider JA, Nelson BC, Atha DH, Jain A, Soliman KF, Aschner M, Mazzio E, Renee Reams R.

Toxicol Lett. 2013 Apr 26;218(3):299-307. doi: 10.1016/j.toxlet.2012.12.024. Epub 2013 Jan 4.

14.

Neurotoxicity of manganese chloride in neonatal and adult CD rats following subchronic (21-day) high-dose oral exposure.

Dorman DC, Struve MF, Vitarella D, Byerly FL, Goetz J, Miller R.

J Appl Toxicol. 2000 May-Jun;20(3):179-87.

PMID:
10797470
15.

Manganese-induced developmental neurotoxicity in the CD rat: is oxidative damage a mechanism of action?

Brenneman KA, Cattley RC, Ali SF, Dorman DC.

Neurotoxicology. 1999 Apr-Jun;20(2-3):477-87.

PMID:
10385906
16.

Role of neurosteroids in experimental 3-nitropropionic acid induced neurotoxicity in rats.

Kumar P, Kumar P, Khan A, Deshmukh R, Lal Sharma P.

Eur J Pharmacol. 2014 Jan 15;723:38-45. doi: 10.1016/j.ejphar.2013.11.036. Epub 2013 Dec 10.

PMID:
24333475
17.

Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity.

Santos AP, Lucas RL, Andrade V, Mateus ML, Milatovic D, Aschner M, Batoreu MC.

Toxicol Appl Pharmacol. 2012 Feb 1;258(3):394-402. doi: 10.1016/j.taap.2011.12.003. Epub 2011 Dec 9.

PMID:
22178737
18.

Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures.

Exil V, Ping L, Yu Y, Chakraborty S, Caito SW, Wells KS, Karki P, Lee E, Aschner M.

PLoS One. 2014 May 2;9(5):e94753. doi: 10.1371/journal.pone.0094753. eCollection 2014.

19.

Postnatal manganese exposure alters dopamine transporter function in adult rats: Potential impact on nonassociative and associative processes.

McDougall SA, Reichel CM, Farley CM, Flesher MM, Der-Ghazarian T, Cortez AM, Wacan JJ, Martinez CE, Varela FA, Butt AE, Crawford CA.

Neuroscience. 2008 Jun 23;154(2):848-60. doi: 10.1016/j.neuroscience.2008.03.070. Epub 2008 Apr 7.

20.

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