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Items: 1 to 20 of 138

1.

In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli.

Nechemia-Arbely Y, Khamaisi M, Rosenberger C, Koesters R, Shina A, Geva C, Shriki A, Klaus S, Rosen S, Rose-John S, Galun E, Axelrod JH, Heyman SN.

Clin Exp Pharmacol Physiol. 2013 Apr;40(4):262-72. doi: 10.1111/1440-1681.12064.

PMID:
23384058
2.

Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.

Khamaisi M, Toukan H, Axelrod JH, Rosenberger C, Skarzinski G, Shina A, Meidan R, Koesters R, Rosen S, Walkinshaw G, Mimura I, Nangaku M, Heyman SN.

Kidney Int. 2015 Apr;87(4):761-70. doi: 10.1038/ki.2014.362. Epub 2014 Dec 3.

PMID:
25469848
3.

Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner.

Kai S, Tanaka T, Daijo H, Harada H, Kishimoto S, Suzuki K, Takabuchi S, Takenaga K, Fukuda K, Hirota K.

Antioxid Redox Signal. 2012 Feb 1;16(3):203-16. doi: 10.1089/ars.2011.3882. Epub 2011 Oct 17.

4.

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys.

Rosenberger C, Mandriota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU.

J Am Soc Nephrol. 2002 Jul;13(7):1721-32.

5.

Action of hypoxia-inducible factor in liver and kidney from mice with Pax8-rtTA-based deletion of von Hippel-Lindau protein.

Mathia S, Paliege A, Koesters R, Peters H, Neumayer HH, Bachmann S, Rosenberger C.

Acta Physiol (Oxf). 2013 Mar;207(3):565-76. doi: 10.1111/apha.12058.

PMID:
23384425
6.

STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.

Jung JE, Kim HS, Lee CS, Shin YJ, Kim YN, Kang GH, Kim TY, Juhnn YS, Kim SJ, Park JW, Ye SK, Chung MH.

Exp Mol Med. 2008 Oct 31;40(5):479-85.

8.

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.

Cancer Res. 2001 Jul 1;61(13):5215-22.

9.

Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells.

Niu G, Briggs J, Deng J, Ma Y, Lee H, Kortylewski M, Kujawski M, Kay H, Cress WD, Jove R, Yu H.

Mol Cancer Res. 2008 Jul;6(7):1099-105. doi: 10.1158/1541-7786.MCR-07-2177.

10.

eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.

Papadakis AI, Paraskeva E, Peidis P, Muaddi H, Li S, Raptis L, Pantopoulos K, Simos G, Koromilas AE.

Cancer Res. 2010 Oct 15;70(20):7820-9. doi: 10.1158/0008-5472.CAN-10-0215. Epub 2010 Oct 5.

11.

STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells.

Jung JE, Lee HG, Cho IH, Chung DH, Yoon SH, Yang YM, Lee JW, Choi S, Park JW, Ye SK, Chung MH.

FASEB J. 2005 Aug;19(10):1296-8. Epub 2005 May 26.

PMID:
15919761
13.

A perylene derivative regulates HIF-1α and Stat3 signaling pathways.

Chen H, Guan Y, Yuan G, Zhang Q, Jing N.

Bioorg Med Chem. 2014 Feb 15;22(4):1496-505. doi: 10.1016/j.bmc.2013.10.018. Epub 2013 Oct 24.

PMID:
24485121
14.

Mechanisms underlying somatostatin receptor 2 down-regulation of vascular endothelial growth factor expression in response to hypoxia in mouse retinal explants.

Mei S, Cammalleri M, Azara D, Casini G, Bagnoli P, Dal Monte M.

J Pathol. 2012 Feb;226(3):519-33. doi: 10.1002/path.3006. Epub 2011 Dec 13.

PMID:
21960021
16.

Regulation of S100A4 expression via the JAK2-STAT3 pathway in rhomboid-phenotype pulmonary arterial smooth muscle cells exposure to hypoxia.

Liu T, Li Y, Lin K, Yin H, He B, Zheng M, Wang G.

Int J Biochem Cell Biol. 2012 Aug;44(8):1337-45. doi: 10.1016/j.biocel.2012.04.017. Epub 2012 Apr 27.

PMID:
22561747
17.

Suppression of STAT3 and HIF-1 alpha mediates anti-angiogenic activity of betulinic acid in hypoxic PC-3 prostate cancer cells.

Shin J, Lee HJ, Jung DB, Jung JH, Lee HJ, Lee EO, Lee SG, Shim BS, Choi SH, Ko SG, Ahn KS, Jeong SJ, Kim SH.

PLoS One. 2011;6(6):e21492. doi: 10.1371/journal.pone.0021492. Epub 2011 Jun 24.

18.

p53 regulates renal expression of HIF-1{alpha} and pVHL under physiological conditions and after ischemia-reperfusion injury.

Sutton TA, Wilkinson J, Mang HE, Knipe NL, Plotkin Z, Hosein M, Zak K, Wittenborn J, Dagher PC.

Am J Physiol Renal Physiol. 2008 Dec;295(6):F1666-77. doi: 10.1152/ajprenal.90304.2008. Epub 2008 Sep 24.

19.

STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells.

Pawlus MR, Wang L, Hu CJ.

Oncogene. 2014 Mar 27;33(13):1670-9. doi: 10.1038/onc.2013.115. Epub 2013 Apr 22.

20.

Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein.

Lei L, Mason S, Liu D, Huang Y, Marks C, Hickey R, Jovin IS, Pypaert M, Johnson RS, Giordano FJ.

Mol Cell Biol. 2008 Jun;28(11):3790-803. doi: 10.1128/MCB.01580-07. Epub 2008 Feb 19.

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