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Items: 1 to 20 of 105

1.

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

Lauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mužinić A, Novokmet M, Polašek O, Gornik O, Krištić J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, Kolčić I, Lukić IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I.

PLoS Genet. 2013;9(1):e1003225. doi: 10.1371/journal.pgen.1003225. Epub 2013 Jan 31.

2.

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns.

Wahl A, van den Akker E, Klaric L, Štambuk J, Benedetti E, Plomp R, Razdorov G, Trbojević-Akmačić I, Deelen J, van Heemst D, Slagboom PE, Vučković F, Grallert H, Krumsiek J, Strauch K, Peters A, Meitinger T, Hayward C, Wuhrer M, Beekman M, Lauc G, Gieger C.

Front Immunol. 2018 Feb 26;9:277. doi: 10.3389/fimmu.2018.00277. eCollection 2018.

3.

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases.

Witoelar A, Jansen IE, Wang Y, Desikan RS, Gibbs JR, Blauwendraat C, Thompson WK, Hernandez DG, Djurovic S, Schork AJ, Bettella F, Ellinghaus D, Franke A, Lie BA, McEvoy LK, Karlsen TH, Lesage S, Morris HR, Brice A, Wood NW, Heutink P, Hardy J, Singleton AB, Dale AM, Gasser T, Andreassen OA, Sharma M; International Parkinson’s Disease Genomics Consortium (IPDGC), North American Brain Expression Consortium (NABEC), and United Kingdom Brain Expression Consortium (UKBEC) Investigators.

JAMA Neurol. 2017 Jul 1;74(7):780-792. doi: 10.1001/jamaneurol.2017.0469.

4.

A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

Ramos PS, Criswell LA, Moser KL, Comeau ME, Williams AH, Pajewski NM, Chung SA, Graham RR, Zidovetzki R, Kelly JA, Kaufman KM, Jacob CO, Vyse TJ, Tsao BP, Kimberly RP, Gaffney PM, Alarcón-Riquelme ME, Harley JB, Langefeld CD; International Consortium on the Genetics of Systemic Erythematosus.

PLoS Genet. 2011 Dec;7(12):e1002406. doi: 10.1371/journal.pgen.1002406. Epub 2011 Dec 8.

5.

Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease.

Klasić M, Markulin D, Vojta A, Samaržija I, Biruš I, Dobrinić P, Ventham NT, Trbojević-Akmačić I, Šimurina M, Štambuk J, Razdorov G, Kennedy NA, Satsangi J, Dias AM, Pinho S, Annese V, Latiano A, D'Inca R; IBD consortium, Lauc G, Zoldoš V.

Clin Epigenetics. 2018 Jun 4;10:75. doi: 10.1186/s13148-018-0507-y. eCollection 2018.

6.

Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome.

Vučković F, Krištić J, Gudelj I, Teruel M, Keser T, Pezer M, Pučić-Baković M, Štambuk J, Trbojević-Akmačić I, Barrios C, Pavić T, Menni C, Wang Y, Zhou Y, Cui L, Song H, Zeng Q, Guo X, Pons-Estel BA, McKeigue P, Leslie Patrick A, Gornik O, Spector TD, Harjaček M, Alarcon-Riquelme M, Molokhia M, Wang W, Lauc G.

Arthritis Rheumatol. 2015 Nov;67(11):2978-89. doi: 10.1002/art.39273.

7.

Defining the genetic control of human blood plasma N-glycome using genome-wide association study.

Sharapov SZ, Tsepilov YA, Klaric L, Mangino M, Thareja G, Shadrina AS, Simurina M, Dagostino C, Dmitrieva J, Vilaj M, Vuckovic F, Pavic T, Stambuk J, Trbojevic-Akmacic I, Kristic J, Simunovic J, Momcilovic A, Campbell H, Doherty M, Dunlop MG, Farrington SM, Pucic-Bakovic M, Gieger C, Allegri M, Louis E, Georges M, Suhre K, Spector T, Williams FMK, Lauc G, Aulchenko YS.

Hum Mol Genet. 2019 Jun 15;28(12):2062-2077. doi: 10.1093/hmg/ddz054.

8.

Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome.

Trbojević Akmačić I, Ventham NT, Theodoratou E, Vučković F, Kennedy NA, Krištić J, Nimmo ER, Kalla R, Drummond H, Štambuk J, Dunlop MG, Novokmet M, Aulchenko Y, Gornik O, Campbell H, Pučić Baković M, Satsangi J, Lauc G; IBD-BIOM Consortium.

Inflamm Bowel Dis. 2015 Jun;21(6):1237-47. doi: 10.1097/MIB.0000000000000372.

9.

Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.

Yarwood A, Viatte S, Okada Y, Plenge R, Yamamoto K; BRAGGSS, RACI, Barton A, Symmons D, Raychaudhuri S, Klareskog L, Gregersen P, Worthington J, Eyre S.

Ann Rheum Dis. 2016 Jan;75(1):317-20. doi: 10.1136/annrheumdis-2014-207210. Epub 2015 Sep 17.

10.

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation.

Shen X, Klarić L, Sharapov S, Mangino M, Ning Z, Wu D, Trbojević-Akmačić I, Pučić-Baković M, Rudan I, Polašek O, Hayward C, Spector TD, Wilson JF, Lauc G, Aulchenko YS.

Nat Commun. 2017 Sep 6;8(1):447. doi: 10.1038/s41467-017-00453-3.

11.

Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases.

Šimurina M, de Haan N, Vučković F, Kennedy NA, Štambuk J, Falck D, Trbojević-Akmačić I, Clerc F, Razdorov G, Khon A, Latiano A, D'Incà R, Danese S, Targan S, Landers C, Dubinsky M; Inflammatory Bowel Disease Biomarkers Consortium, McGovern DPB, Annese V, Wuhrer M, Lauc G.

Gastroenterology. 2018 Apr;154(5):1320-1333.e10. doi: 10.1053/j.gastro.2018.01.002. Epub 2018 Jan 6.

12.

Polyclonal Immunoglobulin G N-Glycosylation in the Pathogenesis of Plasma Cell Disorders.

Mittermayr S, Lê GN, Clarke C, Millán Martín S, Larkin AM, O'Gorman P, Bones J.

J Proteome Res. 2017 Feb 3;16(2):748-762. doi: 10.1021/acs.jproteome.6b00768. Epub 2016 Dec 12.

PMID:
27936757
13.

Altered glycosylation of complexed native IgG molecules is associated with disease activity of systemic lupus erythematosus.

Sjöwall C, Zapf J, von Löhneysen S, Magorivska I, Biermann M, Janko C, Winkler S, Bilyy R, Schett G, Herrmann M, Muñoz LE.

Lupus. 2015 May;24(6):569-81. doi: 10.1177/0961203314558861. Epub 2014 Nov 11.

PMID:
25389233
14.

Characterization of IgG N-glycome profile in colorectal cancer progression by MALDI-TOF-MS.

Liu S, Cheng L, Fu Y, Liu BF, Liu X.

J Proteomics. 2018 Jun 15;181:225-237. doi: 10.1016/j.jprot.2018.04.026. Epub 2018 Apr 23.

PMID:
29698801
15.

Characterization of IgG glycosylation in rheumatoid arthritis patients by MALDI-TOF-MSn and capillary electrophoresis.

Huang C, Liu Y, Wu H, Sun D, Li Y.

Anal Bioanal Chem. 2017 Jun;409(15):3731-3739. doi: 10.1007/s00216-017-0302-1. Epub 2017 Apr 10.

PMID:
28397166
16.

Serum immunoglobulin G Fc region N-glycosylation profiling by matrix-assisted laser desorption/ionization mass spectrometry can distinguish breast cancer patients from cancer-free controls.

Kawaguchi-Sakita N, Kaneshiro-Nakagawa K, Kawashima M, Sugimoto M, Tokiwa M, Suzuki E, Kajihara S, Fujita Y, Iwamoto S, Tanaka K, Toi M.

Biochem Biophys Res Commun. 2016 Jan 22;469(4):1140-5. doi: 10.1016/j.bbrc.2015.12.114. Epub 2015 Dec 29.

PMID:
26740182
17.

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles-Part 2: Mass spectrometric methods.

Reusch D, Haberger M, Falck D, Peter B, Maier B, Gassner J, Hook M, Wagner K, Bonnington L, Bulau P, Wuhrer M.

MAbs. 2015;7(4):732-42. doi: 10.1080/19420862.2015.1045173.

18.

Sialylated Autoantigen-Reactive IgG Antibodies Attenuate Disease Development in Autoimmune Mouse Models of Lupus Nephritis and Rheumatoid Arthritis.

Bartsch YC, Rahmöller J, Mertes MMM, Eiglmeier S, Lorenz FKM, Stoehr AD, Braumann D, Lorenz AK, Winkler A, Lilienthal GM, Petry J, Hobusch J, Steinhaus M, Hess C, Holecska V, Schoen CT, Oefner CM, Leliavski A, Blanchard V, Ehlers M.

Front Immunol. 2018 Jun 6;9:1183. doi: 10.3389/fimmu.2018.01183. eCollection 2018.

19.

Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits.

Corradin O, Saiakhova A, Akhtar-Zaidi B, Myeroff L, Willis J, Cowper-Sal lari R, Lupien M, Markowitz S, Scacheri PC.

Genome Res. 2014 Jan;24(1):1-13. doi: 10.1101/gr.164079.113. Epub 2013 Nov 6.

20.

Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid.

Wuhrer M, Selman MH, McDonnell LA, Kümpfel T, Derfuss T, Khademi M, Olsson T, Hohlfeld R, Meinl E, Krumbholz M.

J Neuroinflammation. 2015 Dec 18;12:235. doi: 10.1186/s12974-015-0450-1.

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