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Items: 1 to 20 of 165

1.

Inhibition of p38/Mk2 signaling pathway improves the anti-inflammatory effect of WIN55 on mouse experimental colitis.

Li YY, Yuece B, Cao HM, Lin HX, Lv S, Chen JC, Ochs S, Sibaev A, Deindl E, Schaefer C, Storr M.

Lab Invest. 2013 Mar;93(3):322-33. doi: 10.1038/labinvest.2012.177. Epub 2013 Feb 4.

2.

Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms.

Michler T, Storr M, Kramer J, Ochs S, Malo A, Reu S, Göke B, Schäfer C.

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15;304(2):G181-92. doi: 10.1152/ajpgi.00133.2012. Epub 2012 Nov 8.

3.

Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK.

Feng YJ, Li YY, Lin XH, Li K, Cao MH.

World J Gastroenterol. 2016 Nov 21;22(43):9515-9524.

4.

Oral administration of the flavonoid myricitrin prevents dextran sulfate sodium-induced experimental colitis in mice through modulation of PI3K/Akt signaling pathway.

Schwanke RC, Marcon R, Meotti FC, Bento AF, Dutra RC, Pizzollatti MG, Calixto JB.

Mol Nutr Food Res. 2013 Nov;57(11):1938-49. doi: 10.1002/mnfr.201300134. Epub 2013 Jul 17.

PMID:
23861337
5.

Cytokine regulation by MAPK activated kinase 2 in keratinocytes exposed to sulfur mustard.

Yego EC, Dillman JF 3rd.

Toxicol In Vitro. 2013 Oct;27(7):2067-75. doi: 10.1016/j.tiv.2013.07.002. Epub 2013 Jul 10.

PMID:
23851002
6.

WIN55,212-2 inhibits production of CX3CL1 by human astrocytes: involvement of p38 MAP kinase.

Sheng WS, Hu S, Ni HT, Rock RB, Peterson PK.

J Neuroimmune Pharmacol. 2009 Jun;4(2):244-8. doi: 10.1007/s11481-009-9147-5. Epub 2009 Feb 12.

7.

Mitogen-activated protein kinase-activated protein kinase 2 deficiency reduces insulin sensitivity in high-fat diet-fed mice.

de Boer JF, Dikkers A, Jurdzinski A, von Felden J, Gaestel M, Bavendiek U, Tietge UJ.

PLoS One. 2014 Sep 18;9(9):e106300. doi: 10.1371/journal.pone.0106300. eCollection 2014.

8.

Post-transcriptional regulation of TNF-induced expression of ICAM-1 and IL-8 in human lung microvascular endothelial cells: an obligatory role for the p38 MAPK-MK2 pathway dissociated with HSP27.

Su X, Ao L, Zou N, Song Y, Yang X, Cai GY, Fullerton DA, Meng X.

Biochim Biophys Acta. 2008 Sep;1783(9):1623-31. doi: 10.1016/j.bbamcr.2008.04.009. Epub 2008 Apr 30.

9.

MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart.

Streicher JM, Ren S, Herschman H, Wang Y.

Circ Res. 2010 Apr 30;106(8):1434-43. doi: 10.1161/CIRCRESAHA.109.213199. Epub 2010 Mar 25.

10.

Dietary squalene supplementation improves DSS-induced acute colitis by downregulating p38 MAPK and NFkB signaling pathways.

Sánchez-Fidalgo S, Villegas I, Rosillo MÁ, Aparicio-Soto M, de la Lastra CA.

Mol Nutr Food Res. 2015 Feb;59(2):284-92. doi: 10.1002/mnfr.201400518. Epub 2014 Dec 12.

PMID:
25387687
11.

Sasa quelpaertensis leaf extract suppresses dextran sulfate sodium-induced colitis in mice by inhibiting the proinflammatory mediators and mitogen-activated protein kinase phosphorylation.

Kim KM, Kim YS, Lim JY, Min SJ, Shin JH, Ko HC, Kim SJ, Lim Y, Kim Y.

Nutr Res. 2014 Oct;34(10):894-905. doi: 10.1016/j.nutres.2014.09.002. Epub 2014 Sep 16.

PMID:
25287291
12.

TRIF signaling stimulates translation of TNF-alpha mRNA via prolonged activation of MK2.

Gais P, Tiedje C, Altmayr F, Gaestel M, Weighardt H, Holzmann B.

J Immunol. 2010 May 15;184(10):5842-8. doi: 10.4049/jimmunol.0902456. Epub 2010 Apr 7.

13.

Regulation of HSP60 and the role of MK2 in a new model of severe experimental pancreatitis.

Li YY, Ochs S, Gao ZR, Malo A, Chen CJ, Lv S, Gallmeier E, Göke B, Schäfer C.

Am J Physiol Gastrointest Liver Physiol. 2009 Nov;297(5):G981-9.

14.

Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway.

O'Dea KP, Dokpesi JO, Tatham KC, Wilson MR, Takata M.

Am J Physiol Lung Cell Mol Physiol. 2011 Nov;301(5):L812-21. doi: 10.1152/ajplung.00092.2011. Epub 2011 Aug 26.

15.

Role of Metallothionein in Post-Burn Inflammation.

Zhang W, Xie Y, Liu W, Xu X, Chen X, Liu H, Liu Y.

Inflammation. 2016 Apr;39(2):768-74. doi: 10.1007/s10753-016-0305-7.

PMID:
26833479
16.

Anti-inflammatory Actions of (+)-3'α-Angeloxy-4'-keto-3',4'-dihydroseselin (Pd-Ib) against Dextran Sulfate Sodium-Induced Colitis in C57BL/6 Mice.

Mu HX, Liu J, Fatima S, Lin CY, Shi XK, Du B, Xiao HT, Fan BM, Bian ZX.

J Nat Prod. 2016 Apr 22;79(4):1056-62. doi: 10.1021/acs.jnatprod.5b01071. Epub 2016 Feb 23.

PMID:
26905227
17.

Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice.

Wang X, Xu L, Wang H, Young PR, Gaestel M, Feuerstein GZ.

J Biol Chem. 2002 Nov 15;277(46):43968-72. Epub 2002 Sep 4.

18.

Activation of protein tyrosine phosphatase non-receptor type 2 by spermidine exerts anti-inflammatory effects in human THP-1 monocytes and in a mouse model of acute colitis.

Morón B, Spalinger M, Kasper S, Atrott K, Frey-Wagner I, Fried M, McCole DF, Rogler G, Scharl M.

PLoS One. 2013 Sep 9;8(9):e73703. doi: 10.1371/journal.pone.0073703. eCollection 2013.

19.

Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.

Zhang J, Dou W, Zhang E, Sun A, Ding L, Wei X, Chou G, Mani S, Wang Z.

Am J Physiol Gastrointest Liver Physiol. 2014 Jan 1;306(1):G27-36. doi: 10.1152/ajpgi.00465.2012. Epub 2013 Nov 14.

20.

Mitogen-activated protein kinase-activated protein kinase 2 in angiotensin II-induced inflammation and hypertension: regulation of oxidative stress.

Ebrahimian T, Li MW, Lemarié CA, Simeone SM, Pagano PJ, Gaestel M, Paradis P, Wassmann S, Schiffrin EL.

Hypertension. 2011 Feb;57(2):245-54. doi: 10.1161/HYPERTENSIONAHA.110.159889. Epub 2010 Dec 20.

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