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Items: 1 to 20 of 167


Abrogation of galectin-4 expression promotes tumorigenesis in colorectal cancer.

Kim SW, Park KC, Jeon SM, Ohn TB, Kim TI, Kim WH, Cheon JH.

Cell Oncol (Dordr). 2013 Apr;36(2):169-78. doi: 10.1007/s13402-013-0124-x.


A microRNA 221- and 222-mediated feedback loop maintains constitutive activation of NFκB and STAT3 in colorectal cancer cells.

Liu S, Sun X, Wang M, Hou Y, Zhan Y, Jiang Y, Liu Z, Cao X, Chen P, Liu Z, Chen X, Tao Y, Xu C, Mao J, Cheng C, Li C, Hu Y, Wang L, Chin YE, Shi Y, Siebenlist U, Zhang X.

Gastroenterology. 2014 Oct;147(4):847-859.e11. doi: 10.1053/j.gastro.2014.06.006.


HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression.

Li Y, Bavarva JH, Wang Z, Guo J, Qian C, Thibodeau SN, Golemis EA, Liu W.

Oncogene. 2011 Jun 9;30(23):2633-43. doi: 10.1038/onc.2010.632.


Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.

Wang D, Fu L, Sun H, Guo L, DuBois RN.

Gastroenterology. 2015 Dec;149(7):1884-1895.e4. doi: 10.1053/j.gastro.2015.07.064.


Spica prunellae promotes cancer cell apoptosis, inhibits cell proliferation and tumor angiogenesis in a mouse model of colorectal cancer via suppression of stat3 pathway.

Lin W, Zheng L, Zhuang Q, Zhao J, Cao Z, Zeng J, Lin S, Xu W, Peng J.

BMC Complement Altern Med. 2013 Jun 24;13:144. doi: 10.1186/1472-6882-13-144.


Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.

Buchert M, Papin M, Bonnans C, Darido C, Raye WS, Garambois V, Pélegrin A, Bourgaux JF, Pannequin J, Joubert D, Hollande F.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2628-33. doi: 10.1073/pnas.0903747107.


Targeted deletion of miR-139-5p activates MAPK, NF-κB and STAT3 signaling and promotes intestinal inflammation and colorectal cancer.

Zou F, Mao R, Yang L, Lin S, Lei K, Zheng Y, Ding Y, Zhang P, Cai G, Liang X, Liu J.

FEBS J. 2016 Apr;283(8):1438-52. doi: 10.1111/febs.13678.


Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.

De Simone V, Franzè E, Ronchetti G, Colantoni A, Fantini MC, Di Fusco D, Sica GS, Sileri P, MacDonald TT, Pallone F, Monteleone G, Stolfi C.

Oncogene. 2015 Jul;34(27):3493-503. doi: 10.1038/onc.2014.286.


ITF2 prevents activation of the β-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.

Shin HW, Choi H, So D, Kim YI, Cho K, Chung HJ, Lee KH, Chun YS, Cho CH, Kang GH, Kim WH, Park JW.

Gastroenterology. 2014 Aug;147(2):430-442.e8. doi: 10.1053/j.gastro.2014.04.047.


Oroxylin A inhibits colitis-associated carcinogenesis through modulating the IL-6/STAT3 signaling pathway.

Yang X, Zhang F, Wang Y, Cai M, Wang Q, Guo Q, Li Z, Hu R.

Inflamm Bowel Dis. 2013 Aug;19(9):1990-2000. doi: 10.1097/MIB.0b013e318293c5e0.


BCL9-2 promotes early stages of intestinal tumor progression.

Brembeck FH, Wiese M, Zatula N, Grigoryan T, Dai Y, Fritzmann J, Birchmeier W.

Gastroenterology. 2011 Oct;141(4):1359-70, 1370.e1-3. doi: 10.1053/j.gastro.2011.06.039.


Disease-related expression of the IL6/STAT3/SOCS3 signalling pathway in ulcerative colitis and ulcerative colitis-related carcinogenesis.

Li Y, de Haar C, Chen M, Deuring J, Gerrits MM, Smits R, Xia B, Kuipers EJ, van der Woude CJ.

Gut. 2010 Feb;59(2):227-35. doi: 10.1136/gut.2009.184176.


Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.

Wang H, Zhao G, Liu X, Sui A, Yang K, Yao R, Wang Z, Shi Q.

J Exp Clin Cancer Res. 2010 Sep 9;29:123. doi: 10.1186/1756-9966-29-123.


ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines.

Bai R, Shi Z, Zhang JW, Li D, Zhu YL, Zheng S.

J Zhejiang Univ Sci B. 2012 Nov;13(11):884-93. doi: 10.1631/jzus.B1200037.


Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB.

Melisi D, Niu J, Chang Z, Xia Q, Peng B, Ishiyama S, Evans DB, Chiao PJ.

Mol Cancer Res. 2009 May;7(5):624-33. doi: 10.1158/1541-7786.MCR-08-0201.


Epigenetic alteration of PRKCDBP in colorectal cancers and its implication in tumor cell resistance to TNFα-induced apoptosis.

Lee JH, Kang MJ, Han HY, Lee MG, Jeong SI, Ryu BK, Ha TK, Her NG, Han J, Park SJ, Lee KY, Kim HJ, Chi SG.

Clin Cancer Res. 2011 Dec 15;17(24):7551-62. doi: 10.1158/1078-0432.CCR-11-1026.


[Correlations of GRIM-19 and its target gene product STAT3 to malignancy of human colorectal carcinoma].

Gong LB, Luo XL, Liu SY, Tao DD, Gong JP, Hu JB.

Ai Zheng. 2007 Jul;26(7):683-7. Chinese.


Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis.

Yu LZ, Wang HY, Yang SP, Yuan ZP, Xu FY, Sun C, Shi RH.

World J Gastroenterol. 2013 May 7;19(17):2638-49. doi: 10.3748/wjg.v19.i17.2638.


BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis.

Southern SL, Collard TJ, Urban BC, Skeen VR, Smartt HJ, Hague A, Oakley F, Townsend PA, Perkins ND, Paraskeva C, Williams AC.

Oncogene. 2012 May 31;31(22):2761-72. doi: 10.1038/onc.2011.452.


Galectin-1 promotes lung cancer progression and chemoresistance by upregulating p38 MAPK, ERK, and cyclooxygenase-2.

Chung LY, Tang SJ, Sun GH, Chou TY, Yeh TS, Yu SL, Sun KH.

Clin Cancer Res. 2012 Aug 1;18(15):4037-47.

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