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Items: 1 to 20 of 117

1.

Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases.

Heimfarth L, Loureiro SO, Pierozan P, de Lima BO, Reis KP, Torres EB, Pessoa-Pureur R.

Metab Brain Dis. 2013 Sep;28(3):429-38. doi: 10.1007/s11011-013-9379-1. Epub 2013 Feb 2.

PMID:
23378107
2.

LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells.

Figarola JL, Singhal J, Rahbar S, Awasthi S, Singhal SS.

Apoptosis. 2014 May;19(5):776-88. doi: 10.1007/s10495-014-0974-3.

3.

Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-κB pathway.

Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, Sun B, Song Y, Lin Y, Peng J, Tang Z.

Vascul Pharmacol. 2017 Apr;91:26-35. doi: 10.1016/j.vph.2016.08.012. Epub 2016 Aug 30.

PMID:
27590258
4.

Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta.

Godbout JP, Pesavento J, Hartman ME, Manson SR, Freund GG.

J Biol Chem. 2002 Jan 25;277(4):2554-61. Epub 2001 Nov 13.

5.
7.

Apoptosis induced by the monomers HEMA and TEGDMA involves formation of ROS and differential activation of the MAP-kinases p38, JNK and ERK.

Samuelsen JT, Dahl JE, Karlsson S, Morisbak E, Becher R.

Dent Mater. 2007 Jan;23(1):34-9. Epub 2006 Jan 23.

PMID:
16430953
8.

Intracellular methylglyoxal induces oxidative damage to pancreatic beta cell line INS-1 cell through Ire1α-JNK and mitochondrial apoptotic pathway.

Liu C, Huang Y, Zhang Y, Chen X, Kong X, Dong Y.

Free Radic Res. 2017 Apr;51(4):337-350. doi: 10.1080/10715762.2017.1289376. Epub 2017 May 10.

PMID:
28488455
9.

Piperlongumine induces apoptotic and autophagic death of the primary myeloid leukemia cells from patients via activation of ROS-p38/JNK pathways.

Xiong XX, Liu JM, Qiu XY, Pan F, Yu SB, Chen XQ.

Acta Pharmacol Sin. 2015 Mar;36(3):362-74. doi: 10.1038/aps.2014.141. Epub 2015 Jan 26.

10.

Edaravone protected human brain microvascular endothelial cells from methylglyoxal-induced injury by inhibiting AGEs/RAGE/oxidative stress.

Li W, Xu H, Hu Y, He P, Ni Z, Xu H, Zhang Z, Dai H.

PLoS One. 2013 Sep 30;8(9):e76025. doi: 10.1371/journal.pone.0076025. eCollection 2013.

11.

Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells.

Kyaw M, Yoshizumi M, Tsuchiya K, Kirima K, Tamaki T.

Hypertens Res. 2001 May;24(3):251-61.

12.

Methylglyoxal mediates vascular inflammation via JNK and p38 in human endothelial cells.

Yamawaki H, Saito K, Okada M, Hara Y.

Am J Physiol Cell Physiol. 2008 Dec;295(6):C1510-7. doi: 10.1152/ajpcell.00252.2008. Epub 2008 Oct 8.

13.

The role of cPLA2 in Methylglyoxal-induced cell apoptosis of HUVECs.

Yuan J, Zhu C, Hong Y, Sun Z, Fang X, Wu B, Li S.

Toxicol Appl Pharmacol. 2017 May 15;323:44-52. doi: 10.1016/j.taap.2017.03.020. Epub 2017 Mar 22.

PMID:
28341536
14.

Low concentration of arsenic could induce caspase-3 mediated head kidney macrophage apoptosis with JNK-p38 activation in Clarias batrachus.

Datta S, Mazumder S, Ghosh D, Dey S, Bhattacharya S.

Toxicol Appl Pharmacol. 2009 Dec 15;241(3):329-38. doi: 10.1016/j.taap.2009.09.007. Epub 2009 Sep 24.

PMID:
19782097
15.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60. Epub 2007 Feb 8.

PMID:
17341418
16.

Compounds blocking methylglyoxal-induced protein modification and brain endothelial injury.

Tóth AE, Tóth A, Walter FR, Kiss L, Veszelka S, Ózsvári B, Puskás LG, Heimesaat MM, Dohgu S, Kataoka Y, Rákhely G, Deli MA.

Arch Med Res. 2014 Nov;45(8):753-64. doi: 10.1016/j.arcmed.2014.10.009. Epub 2014 Nov 13.

PMID:
25446614
17.

Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases.

Caughlan A, Newhouse K, Namgung U, Xia Z.

Toxicol Sci. 2004 Mar;78(1):125-34. Epub 2003 Dec 22.

PMID:
14691213
18.

Methylglyoxal, a reactive glucose metabolite, enhances autophagy flux and suppresses proliferation of human retinal pigment epithelial ARPE-19 cells.

Chang YC, Hsieh MC, Wu HJ, Wu WC, Kao YH.

Toxicol In Vitro. 2015 Oct;29(7):1358-68. doi: 10.1016/j.tiv.2015.05.014. Epub 2015 May 27.

PMID:
26021238
19.

Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species.

Palomeque J, Rueda OV, Sapia L, Valverde CA, Salas M, Petroff MV, Mattiazzi A.

Circ Res. 2009 Dec 4;105(12):1204-12. doi: 10.1161/CIRCRESAHA.109.204172. Epub 2009 Oct 22.

20.

Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: involvement of p22phox and reactive oxygen species.

Viedt C, Soto U, Krieger-Brauer HI, Fei J, Elsing C, Kübler W, Kreuzer J.

Arterioscler Thromb Vasc Biol. 2000 Apr;20(4):940-8.

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