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Items: 1 to 20 of 93

1.

Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA.

Liang JH, Lv W, Li XL, An K, Cushman M, Wang H, Xu YC.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1387-93. doi: 10.1016/j.bmcl.2012.12.070. Epub 2013 Jan 4.

PMID:
23375796
2.

Synthesis, antibacterial activity and docking of 14-membered 9-O-(3-arylalkyl) oxime 11,12-cyclic carbonate ketolides.

Liang JH, An K, Lv W, Cushman M, Wang H, Xu YC.

Eur J Med Chem. 2013 Jan;59:54-63. doi: 10.1016/j.ejmech.2012.10.054. Epub 2012 Nov 8.

PMID:
23202851
3.

Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides.

Pavlović D, Mutak S.

J Med Chem. 2010 Aug 12;53(15):5868-80. doi: 10.1021/jm100711p.

PMID:
20684614
4.

Synthesis and antibacterial activities of 6-O-methylerythromycin A 9-O-(3-aryl-2-propenyl) oxime ketolide, 2,3-enol ether, and alkylide analogues.

Liang JH, Dong LJ, Wang H, An K, Li XL, Yang L, Yao GW, Xu YC.

Eur J Med Chem. 2010 Sep;45(9):3627-35. doi: 10.1016/j.ejmech.2010.05.008. Epub 2010 May 12.

PMID:
20627377
5.

9-Oxime-3-ketolides: modification at the C-11,12-diol moiety and antibacterial activities against key respiratory pathogens.

Nomura T, Yasukata T, Narukawa Y, Uotani K.

Bioorg Med Chem. 2005 Nov 1;13(21):6054-63.

PMID:
15994088
6.

Studies on macrolide antibiotics I. Synthesis and antibacterial activity of erythromycin A 9-O-substituted oxime ether derivatives against Mycobacterium avium complex.

Nishimoto A, Narita K, Ohmoto S, Takahashi Y, Yoshizumi S, Yoshida T, Kado N, Okezaki E, Kato H.

Chem Pharm Bull (Tokyo). 2001 Sep;49(9):1120-7.

7.

Synthesis and antibacterial evaluation of a novel series of 10-hydroxyl ketolide derivatives.

Jiang JW, Sun Y, Nie Y, Zhi HJ, Zhang XJ, Li X, Sun HP, You QD.

Bioorg Med Chem Lett. 2013 Jun 1;23(11):3452-7. doi: 10.1016/j.bmcl.2013.03.057. Epub 2013 Apr 3.

PMID:
23591116
8.

Synthesis and antibacterial activity of novel modified 5-O-mycaminose 14-membered ketolides.

Xu Y, Chen X, Zhu D, Liu Y, Zhao Z, Jin L, Liu C, Lei P.

Eur J Med Chem. 2013 Nov;69:174-81. doi: 10.1016/j.ejmech.2013.08.023. Epub 2013 Aug 23.

PMID:
24021890
9.

Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides.

Sugimoto T, Shimazaki Y, Manaka A, Tanikawa T, Suzuki K, Nanaumi K, Kaneda Y, Yamasaki Y, Sugiyama H.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5739-43. doi: 10.1016/j.bmcl.2012.06.092. Epub 2012 Jul 6.

PMID:
22858102
10.
11.

Synthesis and antibacterial activity of novel ketolides with 11,12-sulfur contained aryl alkyl side chains.

Chen XZ, Xu P, Liu L, Zheng D, Lei PS.

Eur J Med Chem. 2011 Jan;46(1):208-17. doi: 10.1016/j.ejmech.2010.11.004. Epub 2010 Nov 10.

PMID:
21130543
12.

Design, synthesis and antibacterial activity of novel ketolides bearing an aryltetrazolyl-substituted alkyl side chain.

Song QL, Guo BQ, Zhang W, Lan P, Sun PH, Chen WM.

J Antibiot (Tokyo). 2011 Aug;64(8):571-81. doi: 10.1038/ja.2011.50. Epub 2011 Jul 20.

PMID:
21772308
13.

Design, synthesis and structure-bactericidal activity relationships of novel 9-oxime ketolides and reductive epimers of acylides.

Tian JC, Han X, Lv W, Li YX, Wang H, Fan BZ, Cushman M, Liang JH.

Bioorg Med Chem Lett. 2017 Apr 1;27(7):1513-1524. doi: 10.1016/j.bmcl.2017.02.041. Epub 2017 Feb 20.

PMID:
28256375
14.

[Advance in synthesis of ketolides, a new class of erythromycin derivatives].

Lei PS, Xu P, Liu L.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Aug;26(4):467-73. Review. Chinese.

PMID:
15379279
15.
16.

Design, synthesis, and anti-Helicobacter pylori activity of erythromycin A (E)-9-oxime ether derivatives.

Nam G, Kang TW, Shin JH, Choi KI.

Bioorg Med Chem Lett. 2006 Feb;16(3):569-72. Epub 2005 Nov 4.

PMID:
16275089
17.

Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity.

Xu P, Liu L, Chen XZ, Li Y, Liu J, Jin ZP, Wang GQ, Lei PS.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4079-83. doi: 10.1016/j.bmcl.2009.06.023. Epub 2009 Jun 13.

PMID:
19560350
18.

Synthesis of 9-oxime-11,12-carbamate ketolides through a novel N-deamination reaction of 11,12-hydrazonocarbamate ketolide.

Denis A, Pejac JM, Bretin F, Bonnefoy A.

Bioorg Med Chem. 2003 May 29;11(11):2389-94.

PMID:
12735984
19.

Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials.

Pavlović D, Fajdetić A, Mutak S.

Bioorg Med Chem. 2010 Dec 15;18(24):8566-82. doi: 10.1016/j.bmc.2010.10.024. Epub 2010 Oct 20.

PMID:
21055953
20.

Synthesis and antibacterial activity of C-12 pyrazolinyl spiro ketolides.

Hu L, Lan P, Song QL, Huang ZJ, Sun PH, Zhuo C, Wang Y, Xiao S, Chen WM.

Eur J Med Chem. 2010 Dec;45(12):5943-9. doi: 10.1016/j.ejmech.2010.09.060. Epub 2010 Oct 7.

PMID:
20970894

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