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Items: 1 to 20 of 110

1.
2.

Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W).

Kim JH, Yoon S, Park M, Park HO, Ko JJ, Lee K, Bae J.

Oncogene. 2011 Apr 7;30(14):1653-63. doi: 10.1038/onc.2010.541.

PMID:
21119601
3.

Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter.

Fleming NI, Knower KC, Lazarus KA, Fuller PJ, Simpson ER, Clyne CD.

PLoS One. 2010 Dec 20;5(12):e14389. doi: 10.1371/journal.pone.0014389.

4.

FOXL2, GATA4, and SMAD3 co-operatively modulate gene expression, cell viability and apoptosis in ovarian granulosa cell tumor cells.

Anttonen M, Pihlajoki M, Andersson N, Georges A, L'hôte D, Vattulainen S, Färkkilä A, Unkila-Kallio L, Veitia RA, Heikinheimo M.

PLoS One. 2014 Jan 9;9(1):e85545. doi: 10.1371/journal.pone.0085545.

5.

The transcriptional targets of mutant FOXL2 in granulosa cell tumours.

Rosario R, Araki H, Print CG, Shelling AN.

PLoS One. 2012;7(9):e46270. doi: 10.1371/journal.pone.0046270.

6.

FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors.

Cheng JC, Chang HM, Qiu X, Fang L, Leung PC.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):537-42. doi: 10.1016/j.bbrc.2013.12.010.

PMID:
24332943
7.

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

Shah SP, Köbel M, Senz J, Morin RD, Clarke BA, Wiegand KC, Leung G, Zayed A, Mehl E, Kalloger SE, Sun M, Giuliany R, Yorida E, Jones S, Varhol R, Swenerton KD, Miller D, Clement PB, Crane C, Madore J, Provencher D, Leung P, DeFazio A, Khattra J, Turashvili G, Zhao Y, Zeng T, Glover JN, Vanderhyden B, Zhao C, Parkinson CA, Jimenez-Linan M, Bowtell DD, Mes-Masson AM, Brenton JD, Aparicio SA, Boyd N, Hirst M, Gilks CB, Marra M, Huntsman DG.

N Engl J Med. 2009 Jun 25;360(26):2719-29. doi: 10.1056/NEJMoa0902542.

8.

The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary.

Jamieson S, Butzow R, Andersson N, Alexiadis M, Unkila-Kallio L, Heikinheimo M, Fuller PJ, Anttonen M.

Mod Pathol. 2010 Nov;23(11):1477-85. doi: 10.1038/modpathol.2010.145.

9.

The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.

Schrader KA, Gorbatcheva B, Senz J, Heravi-Moussavi A, Melnyk N, Salamanca C, Maines-Bandiera S, Cooke SL, Leung P, Brenton JD, Gilks CB, Monahan J, Huntsman DG.

PLoS One. 2009 Nov 24;4(11):e7988. doi: 10.1371/journal.pone.0007988.

10.

Mutational analysis of FOXL2 p.C134W and expression of bone morphogenetic protein 2 in Japanese patients with granulosa cell tumor of ovary.

Oseto K, Suzumori N, Nishikawa R, Nishikawa H, Arakawa A, Ozaki Y, Asai H, Kawai M, Mizuno K, Takahashi S, Shirai T, Yamada-Namikawa C, Nakanishi M, Kajiyama H, Kikkawa F, Sugiura-Ogasawara M.

J Obstet Gynaecol Res. 2014 May;40(5):1197-204. doi: 10.1111/jog.12324.

PMID:
24689977
11.

The FOXL2 mutation (c.402C>G) in adult-type ovarian granulosa cell tumors of three Japanese patients: clinical report and review of the literature.

Takahashi A, Kimura F, Yamanaka A, Takebayashi A, Kita N, Takahashi K, Murakami T.

Tohoku J Exp Med. 2013;231(4):243-50. Review.

12.

Absence of a FOXL2 mutation (402C→G) in the blood of adult-type granulosa cell tumor patients possessing the FOXL2 mutation.

Lee S, Kim TH, Won M, Ko JJ, Rho J, Lee K, Bae J.

Int J Gynecol Cancer. 2010 Nov;20(8):1341-3. doi: 10.1111/IGC.0b013e3181ff3e73.

PMID:
21051974
13.

Functional exploration of the adult ovarian granulosa cell tumor-associated somatic FOXL2 mutation p.Cys134Trp (c.402C>G).

Benayoun BA, Caburet S, Dipietromaria A, Georges A, D'Haene B, Pandaranayaka PJ, L'Hôte D, Todeschini AL, Krishnaswamy S, Fellous M, De Baere E, Veitia RA.

PLoS One. 2010 Jan 20;5(1):e8789. doi: 10.1371/journal.pone.0008789.

14.

The role of FOXL2 in the pathogenesis of adult ovarian granulosa cell tumours.

Rosario R, Cohen PA, Shelling AN.

Gynecol Oncol. 2014 May;133(2):382-7. doi: 10.1016/j.ygyno.2013.12.012. Review.

PMID:
24342437
15.

Identification and Validation of Differential Phosphorylation Sites of the Nuclear FOXL2 Protein as Potential Novel Biomarkers for Adult-Type Granulosa Cell Tumors.

Suh DS, Oh HK, Kim JH, Park S, Shin E, Lee K, Kim YH, Bae J.

J Proteome Res. 2015 Jun 5;14(6):2446-56. doi: 10.1021/pr501230b.

PMID:
25871347
16.

Comparative study of microRNA regulation on FOXL2 between adult-type and juvenile-type granulosa cell tumours in vitro.

Rosario R, Blenkiron C, Shelling AN.

Gynecol Oncol. 2013 Apr;129(1):209-15. doi: 10.1016/j.ygyno.2012.12.034.

PMID:
23280087
17.

Mutational analysis (c.402C>G) of the FOXL2 gene and immunohistochemical expression of the FOXL2 protein in testicular adult type granulosa cell tumors and incompletely differentiated sex cord stromal tumors.

Hes O, Vaněček T, Petersson F, Grossmann P, Hora M, Perez Montiel DM, Steiner P, Dvořák M, Michal M.

Appl Immunohistochem Mol Morphol. 2011 Jul;19(4):347-51. doi: 10.1097/PAI.0b013e3182039ef2.

PMID:
21293260
18.
19.

Effects of an inhibitor of the γ-secretase complex on proliferation and apoptotic parameters in a FOXL2-mutated granulosa tumor cell line (KGN).

Irusta G, Pazos MC, Abramovich D, De Zúñiga I, Parborell F, Tesone M.

Biol Reprod. 2013 Jul 11;89(1):9. doi: 10.1095/biolreprod.113.108100. Erratum in: Biol Reprod. 2014 Dec;91(6):138. Maidana, Camila Pazos [corrected to Pazos, Maria Camila].

PMID:
23699387
20.

Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors.

Leung DT, Fuller PJ, Chu S.

Int J Biochem Cell Biol. 2016 Mar;72:51-4. doi: 10.1016/j.biocel.2016.01.003. Review.

PMID:
26791928

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