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Items: 1 to 20 of 138


Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach.

Chung KY, Day PW, Vélez-Ruiz G, Sunahara RK, Kobilka BK.

PLoS One. 2013;8(1):e54942. doi: 10.1371/journal.pone.0054942. Epub 2013 Jan 25.


CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor.

Kittanakom S, Barrios-Rodiles M, Petschnigg J, Arnoldo A, Wong V, Kotlyar M, Heisler LE, Jurisica I, Wrana JL, Nislow C, Stagljar I.

Biochem Biophys Res Commun. 2014 Mar 21;445(4):746-56. doi: 10.1016/j.bbrc.2014.02.033. Epub 2014 Feb 19.


Potential Signal Transduction Regulation by HDL of the β2-Adrenergic Receptor Pathway. Implications in Selected Pathological Situations.

Niesor EJ, Benghozi R.

Arch Med Res. 2015 Jul;46(5):361-71. doi: 10.1016/j.arcmed.2015.05.008. Epub 2015 May 23. Review.


A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.

Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, Sunahara RK.

Proc Natl Acad Sci U S A. 2007 May 1;104(18):7682-7. Epub 2007 Apr 23.


Identification of a novel protein-protein interaction motif mediating interaction of GPCR-associated sorting proteins with G protein-coupled receptors.

Bornert O, Møller TC, Boeuf J, Candusso MP, Wagner R, Martinez KL, Simonin F.

PLoS One. 2013;8(2):e56336. doi: 10.1371/journal.pone.0056336. Epub 2013 Feb 18.


Cell-based high-throughput screening assay system for monitoring G protein-coupled receptor activation using beta-galactosidase enzyme complementation technology.

Yan YX, Boldt-Houle DM, Tillotson BP, Gee MA, D'Eon BJ, Chang XJ, Olesen CE, Palmer MA.

J Biomol Screen. 2002 Oct;7(5):451-9.


Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations.

Seifert R, Wenzel-Seifert K, Gether U, Kobilka BK.

J Pharmacol Exp Ther. 2001 Jun;297(3):1218-26.


Techniques for the discovery of GPCR-associated protein complexes.

Daulat A, Maurice P, Jockers R.

Methods Enzymol. 2013;521:329-45. doi: 10.1016/B978-0-12-391862-8.00018-1.


The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex.

Yao XJ, Vélez Ruiz G, Whorton MR, Rasmussen SG, DeVree BT, Deupi X, Sunahara RK, Kobilka B.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9501-6. doi: 10.1073/pnas.0811437106. Epub 2009 May 22.


Subtype-specific roles of phospholipase C-β via differential interactions with PDZ domain proteins.

Kim JK, Lim S, Kim J, Kim S, Kim JH, Ryu SH, Suh PG.

Adv Enzyme Regul. 2011;51(1):138-51. doi: 10.1016/j.advenzreg.2010.10.004. Epub 2010 Oct 28. Review.


A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

Maurice P, Daulat AM, Broussard C, Mozo J, Clary G, Hotellier F, Chafey P, Guillaume JL, Ferry G, Boutin JA, Delagrange P, Camoin L, Jockers R.

Mol Cell Proteomics. 2008 Aug;7(8):1556-69. doi: 10.1074/mcp.M700435-MCP200. Epub 2008 Apr 29.


MAS C-Terminal Tail Interacting Proteins Identified by Mass Spectrometry- Based Proteomic Approach.

Tirupula KC, Zhang D, Osbourne A, Chatterjee A, Desnoyer R, Willard B, Karnik SS.

PLoS One. 2015 Oct 20;10(10):e0140872. doi: 10.1371/journal.pone.0140872. eCollection 2015.


A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models.

Sgourakis NG, Bagos PG, Papasaikas PK, Hamodrakas SJ.

BMC Bioinformatics. 2005 Apr 22;6:104.


Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery?

Smith TH, Sim-Selley LJ, Selley DE.

Br J Pharmacol. 2010 Jun;160(3):454-66. doi: 10.1111/j.1476-5381.2010.00777.x. Review.


Biochemical Large-Scale Interaction Analysis of Murine Olfactory Receptors and Associated Signaling Proteins with Post-Synaptic Density 95, Drosophila Discs Large, Zona-Occludens 1 (PDZ) Domains.

Jansen F, Kalbe B, Scholz P, Fränzel B, Osterloh M, Wolters D, Hatt H, Neuhaus EM, Osterloh S.

Mol Cell Proteomics. 2015 Aug;14(8):2072-84. doi: 10.1074/mcp.M114.045997. Epub 2015 May 15.


Conformational analysis of g protein-coupled receptor signaling by hydrogen/deuterium exchange mass spectrometry.

Li S, Lee SY, Chung KY.

Methods Enzymol. 2015;557:261-78. doi: 10.1016/bs.mie.2014.12.004. Epub 2015 Mar 29.


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