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Items: 1 to 20 of 176

1.

Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents.

Menendez JA, Joven J, Aragonès G, Barrajón-Catalán E, Beltrán-Debón R, Borrás-Linares I, Camps J, Corominas-Faja B, Cufí S, Fernández-Arroyo S, Garcia-Heredia A, Hernández-Aguilera A, Herranz-López M, Jiménez-Sánchez C, López-Bonet E, Lozano-Sánchez J, Luciano-Mateo F, Martin-Castillo B, Martin-Paredero V, Pérez-Sánchez A, Oliveras-Ferraros C, Riera-Borrull M, Rodríguez-Gallego E, Quirantes-Piné R, Rull A, Tomás-Menor L, Vazquez-Martin A, Alonso-Villaverde C, Micol V, Segura-Carretero A.

Cell Cycle. 2013 Feb 15;12(4):555-78. doi: 10.4161/cc.23756. Epub 2013 Jan 31.

2.

Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals.

Vazquez-Martin A, Fernández-Arroyo S, Cufí S, Oliveras-Ferraros C, Lozano-Sánchez J, Vellón L, Micol V, Joven J, Segura-Carretero A, Menendez JA.

Rejuvenation Res. 2012 Feb;15(1):3-21. doi: 10.1089/rej.2011.1203. Epub 2012 Jan 9.

3.
4.

Computer-aided discovery of biological activity spectra for anti-aging and anti-cancer olive oil oleuropeins.

Corominas-Faja B, Santangelo E, Cuyàs E, Micol V, Joven J, Ariza X, Segura-Carretero A, García J, Menendez JA.

Aging (Albany NY). 2014 Sep;6(9):731-41.

5.

tabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO).

Menendez JA, Vazquez-Martin A, Garcia-Villalba R, Carrasco-Pancorbo A, Oliveras-Ferraros C, Fernandez-Gutierrez A, Segura-Carretero A.

BMC Cancer. 2008 Dec 18;8:377. doi: 10.1186/1471-2407-8-377.

6.

Crude phenolic extracts from extra virgin olive oil circumvent de novo breast cancer resistance to HER1/HER2-targeting drugs by inducing GADD45-sensed cellular stress, G2/M arrest and hyperacetylation of Histone H3.

Oliveras-Ferraros C, Fernández-Arroyo S, Vazquez-Martin A, Lozano-Sánchez J, Cufí S, Joven J, Micol V, Fernández-Gutiérrez A, Segura-Carretero A, Menendez JA.

Int J Oncol. 2011 Jun;38(6):1533-47. doi: 10.3892/ijo.2011.993. Epub 2011 Mar 30.

PMID:
21455577
7.

Nutraceutical properties of extra-virgin olive oil: a natural remedy for age-related disease?

Virruso C, Accardi G, Colonna-Romano G, Candore G, Vasto S, Caruso C.

Rejuvenation Res. 2014 Apr;17(2):217-20. doi: 10.1089/rej.2013.1532. Review.

PMID:
24219356
8.

Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells.

Menendez JA, Vazquez-Martin A, Colomer R, Brunet J, Carrasco-Pancorbo A, Garcia-Villalba R, Fernandez-Gutierrez A, Segura-Carretero A.

BMC Cancer. 2007 May 9;7:80.

9.

The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology.

Grossi C, Rigacci S, Ambrosini S, Ed Dami T, Luccarini I, Traini C, Failli P, Berti A, Casamenti F, Stefani M.

PLoS One. 2013 Aug 8;8(8):e71702. doi: 10.1371/journal.pone.0071702. eCollection 2013.

10.

Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.

Menendez JA, Vazquez-Martin A, Oliveras-Ferraros C, Garcia-Villalba R, Carrasco-Pancorbo A, Fernandez-Gutierrez A, Segura-Carretero A.

Int J Mol Med. 2008 Oct;22(4):433-9.

PMID:
18813848
11.

Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight.

Rigacci S, Miceli C, Nediani C, Berti A, Cascella R, Pantano D, Nardiello P, Luccarini I, Casamenti F, Stefani M.

Oncotarget. 2015 Nov 3;6(34):35344-57. doi: 10.18632/oncotarget.6119.

12.

Extra virgin olive oil intake delays the development of amyotrophic lateral sclerosis associated with reduced reticulum stress and autophagy in muscle of SOD1G93A mice.

Oliván S, Martínez-Beamonte R, Calvo AC, Surra JC, Manzano R, Arnal C, Osta R, Osada J.

J Nutr Biochem. 2014 Aug;25(8):885-92. doi: 10.1016/j.jnutbio.2014.04.005. Epub 2014 May 2.

PMID:
24917047
13.

Literature review on production process to obtain extra virgin olive oil enriched in bioactive compounds. Potential use of byproducts as alternative sources of polyphenols.

Frankel E, Bakhouche A, Lozano-Sánchez J, Segura-Carretero A, Fernández-Gutiérrez A.

J Agric Food Chem. 2013 Jun 5;61(22):5179-88. doi: 10.1021/jf400806z. Epub 2013 May 20. Review.

PMID:
23656613
14.

Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines.

Fini L, Hotchkiss E, Fogliano V, Graziani G, Romano M, De Vol EB, Qin H, Selgrad M, Boland CR, Ricciardiello L.

Carcinogenesis. 2008 Jan;29(1):139-46. Epub 2007 Nov 13.

PMID:
17999988
15.

In vitro effects of extracts of extra virgin olive oil on human colon cancer cells.

Pampaloni B, Mavilia C, Fabbri S, Romani A, Ieri F, Tanini A, Tonelli F, Brandi ML.

Nutr Cancer. 2014;66(7):1228-36. doi: 10.1080/01635581.2014.951727. Epub 2014 Sep 10.

PMID:
25207387
16.

Olive Oil and the Hallmarks of Aging.

Fernández del Río L, Gutiérrez-Casado E, Varela-López A, Villalba JM.

Molecules. 2016 Jan 29;21(2):163. doi: 10.3390/molecules21020163. Review.

17.

Extra virgin olive oil polyphenolic extracts downregulate inflammatory responses in LPS-activated murine peritoneal macrophages suppressing NFκB and MAPK signalling pathways.

Cárdeno A, Sánchez-Hidalgo M, Aparicio-Soto M, Sánchez-Fidalgo S, Alarcón-de-la-Lastra C.

Food Funct. 2014 Jun;5(6):1270-7. doi: 10.1039/c4fo00014e. Epub 2014 Apr 17.

PMID:
24740524
18.

Long-term dietary extra-virgin olive oil rich in polyphenols reverses age-related dysfunctions in motor coordination and contextual memory in mice: role of oxidative stress.

Pitozzi V, Jacomelli M, Catelan D, Servili M, Taticchi A, Biggeri A, Dolara P, Giovannelli L.

Rejuvenation Res. 2012 Dec;15(6):601-12. doi: 10.1089/rej.2012.1346. Epub 2012 Nov 16.

PMID:
22950431
19.

Alternariol-induced cytotoxicity in Caco-2 cells. Protective effect of the phenolic fraction from virgin olive oil.

Chiesi C, Fernandez-Blanco C, Cossignani L, Font G, Ruiz MJ.

Toxicon. 2015 Jan;93:103-11. doi: 10.1016/j.toxicon.2014.11.230. Epub 2014 Nov 21.

PMID:
25451539
20.

Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers.

Karkoula E, Skantzari A, Melliou E, Magiatis P.

J Agric Food Chem. 2014 Jan 22;62(3):600-7. doi: 10.1021/jf404421p. Epub 2014 Jan 13.

PMID:
24384036

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