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Items: 1 to 20 of 90

1.

Metabolomics coupled with proteomics advancing drug discovery toward more agile development of targeted combination therapies.

Wang X, Zhang A, Wang P, Sun H, Wu G, Sun W, Lv H, Jiao G, Xu H, Yuan Y, Liu L, Zou D, Wu Z, Han Y, Yan G, Dong W, Wu F, Dong T, Yu Y, Zhang S, Wu X, Tong X, Meng X.

Mol Cell Proteomics. 2013 May;12(5):1226-38. doi: 10.1074/mcp.M112.021683. Epub 2013 Jan 29.

2.

Metabolomics and proteomics annotate therapeutic properties of geniposide: targeting and regulating multiple perturbed pathways.

Wang X, Zhang A, Yan G, Sun W, Han Y, Sun H.

PLoS One. 2013 Aug 15;8(8):e71403. doi: 10.1371/journal.pone.0071403. eCollection 2013.

3.

An in vivo analysis of the therapeutic and synergistic properties of Chinese medicinal formula Yin-Chen-Hao-Tang based on its active constituents.

Zhang A, Sun H, Yuan Y, Sun W, Jiao G, Wang X.

Fitoterapia. 2011 Dec;82(8):1160-8. doi: 10.1016/j.fitote.2011.07.014. Epub 2011 Jul 29.

PMID:
21835230
4.

Advancing drug discovery and development from active constituents of yinchenhao tang, a famous traditional chinese medicine formula.

Zhang A, Sun H, Qiu S, Wang X.

Evid Based Complement Alternat Med. 2013;2013:257909. doi: 10.1155/2013/257909. Epub 2013 Sep 26. Review.

5.

Simultaneous in vivo RP-HPLC-DAD quantification of multiple-component and drug-drug interaction by pharmacokinetics, using 6,7-dimethylesculetin, geniposide and rhein as examples.

Zhang A, Sun H, Wang X, Jiao G, Yuan Y, Sun W.

Biomed Chromatogr. 2012 Jul;26(7):844-50. doi: 10.1002/bmc.1739. Epub 2011 Nov 8.

PMID:
22068685
6.

Metabolomics coupled with pattern recognition and pathway analysis on potential biomarkers in liver injury and hepatoprotective effects of yinchenhao.

Sun H, Zhang AH, Zou DX, Sun WJ, Wu XH, Wang XJ.

Appl Biochem Biotechnol. 2014 Jun;173(4):857-69. doi: 10.1007/s12010-014-0903-5. Epub 2014 Apr 13.

PMID:
24728784
7.

Potentiating therapeutic effects by enhancing synergism based on active constituents from traditional medicine.

Zhang A, Sun H, Wang X.

Phytother Res. 2014 Apr;28(4):526-33. doi: 10.1002/ptr.5032. Epub 2013 Aug 1. Review.

PMID:
23913598
8.

Ingenuity pathways analysis of urine metabolomics phenotypes toxicity of Chuanwu in Wistar rats by UPLC-Q-TOF-HDMS coupled with pattern recognition methods.

Dong H, Zhang A, Sun H, Wang H, Lu X, Wang M, Ni B, Wang X.

Mol Biosyst. 2012 Apr;8(4):1206-21. doi: 10.1039/c1mb05366c. Epub 2012 Jan 27.

PMID:
22282765
9.
10.

Metabonomic profiles delineate the effect of traditional Chinese medicine sini decoction on myocardial infarction in rats.

Tan G, Liao W, Dong X, Yang G, Zhu Z, Li W, Chai Y, Lou Z.

PLoS One. 2012;7(4):e34157. doi: 10.1371/journal.pone.0034157. Epub 2012 Apr 6.

11.

Investigation of the therapeutic effectiveness of active components in Sini decoction by a comprehensive GC/LC-MS based metabolomics and network pharmacology approaches.

Chen S, Wu S, Li W, Chen X, Dong X, Tan G, Zhang H, Hong Z, Zhu Z, Chai Y.

Mol Biosyst. 2014 Dec;10(12):3310-21. doi: 10.1039/c4mb00048j.

PMID:
25315049
12.

Study on major antitumor components in Yinchenhao decoction in vitro and in vivo based on hollow fiber cell fishing coupled with high performance liquid chromatography.

Wu D, Chen X, Hu S, Bai X.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Aug 15;1060:118-125. doi: 10.1016/j.jchromb.2017.06.003. Epub 2017 Jun 6.

PMID:
28609699
13.

Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases.

Li JY, Cao HY, Sun L, Sun RF, Wu C, Bian YQ, Dong S, Liu P, Sun MY.

World J Gastroenterol. 2017 Feb 21;23(7):1125-1138. doi: 10.3748/wjg.v23.i7.1125. Review.

14.
15.

Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach.

Collins BC, Miller CA, Sposny A, Hewitt P, Wells M, Gallagher WM, Pennington SR.

Mol Cell Proteomics. 2012 Aug;11(8):394-410. doi: 10.1074/mcp.M111.016493. Epub 2012 Apr 23.

16.

Dynamic metabolic profiling of urine biomarkers in rats with alcohol‑induced liver damage following treatment with Zhi‑Zi‑Da‑Huang decoction.

An L, Lang Q, Shen W, Shi Q, Feng F.

Mol Med Rep. 2016 Sep;14(3):2093-100. doi: 10.3892/mmr.2016.5494. Epub 2016 Jul 11.

PMID:
27430289
17.

Metabolomics: towards understanding traditional Chinese medicine.

Zhang A, Sun H, Wang Z, Sun W, Wang P, Wang X.

Planta Med. 2010 Dec;76(17):2026-35. doi: 10.1055/s-0030-1250542. Epub 2010 Nov 5. Review.

PMID:
21058239
18.

Herb medicine Yin-Chen-Hao-Tang ameliorates hepatic fibrosis in bile duct ligation rats.

Lee TY, Chang HH, Chen JH, Hsueh ML, Kuo JJ.

J Ethnopharmacol. 2007 Jan 19;109(2):318-24. Epub 2006 Aug 5.

PMID:
16989967
19.

Proteomic investigation of signatures for geniposide-induced hepatotoxicity.

Wei J, Zhang F, Zhang Y, Cao C, Li X, Li D, Liu X, Yang H, Huang L.

J Proteome Res. 2014 Dec 5;13(12):5724-33. doi: 10.1021/pr5007119. Epub 2014 Oct 30.

PMID:
25336395
20.

Evaluation study on urine metabolomics in yinhuang rat model induced by triplet factors of rhubarb, ethanol, and α-nephthylisothiolyanate.

Tong X, Sun H, Yan GL, Dong W, Sun WJ, Yu Y, Wang P, Han Y, Wang XJ.

Chin J Integr Med. 2011 May;17(5):369-75. doi: 10.1007/s11655-011-0728-9. Epub 2011 May 25.

PMID:
21611901

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