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Items: 1 to 20 of 114


Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences.

Günther K, Rust M, Leers J, Boettger T, Scharfe M, Jarek M, Bartkuhn M, Renkawitz R.

Nucleic Acids Res. 2013 Mar 1;41(5):3010-21. doi: 10.1093/nar/gkt035. Epub 2013 Jan 29.


MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.

Jin SG, Jiang CL, Rauch T, Li H, Pfeifer GP.

J Biol Chem. 2005 Apr 1;280(13):12700-9. Epub 2005 Jan 27.


Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.

Hendrich B, Guy J, Ramsahoye B, Wilson VA, Bird A.

Genes Dev. 2001 Mar 15;15(6):710-23.


MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

Le Guezennec X, Vermeulen M, Brinkman AB, Hoeijmakers WA, Cohen A, Lasonder E, Stunnenberg HG.

Mol Cell Biol. 2006 Feb;26(3):843-51.


MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex.

Jiang CL, Jin SG, Pfeifer GP.

J Biol Chem. 2004 Dec 10;279(50):52456-64. Epub 2004 Sep 28.


DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells.

Hainer SJ, McCannell KN, Yu J, Ee LS, Zhu LJ, Rando OJ, Fazzio TG.

Elife. 2016 Nov 16;5. pii: e21964. doi: 10.7554/eLife.21964.


MBD3 localizes at promoters, gene bodies and enhancers of active genes.

Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA.

PLoS Genet. 2013;9(12):e1004028. doi: 10.1371/journal.pgen.1004028. Epub 2013 Dec 26.


Probing the dynamic distribution of bound states for methylcytosine-binding domains on DNA.

Cramer JM, Scarsdale JN, Walavalkar NM, Buchwald WA, Ginder GD, Williams DC Jr.

J Biol Chem. 2014 Jan 17;289(3):1294-302. doi: 10.1074/jbc.M113.512236. Epub 2013 Dec 4.


CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level.

Pan H, Bilinovich SM, Kaur P, Riehn R, Wang H, Williams DC Jr.

Nucleic Acids Res. 2017 Sep 6;45(15):9164-9177. doi: 10.1093/nar/gkx548.


Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression.

Ghoshal K, Majumder S, Datta J, Motiwala T, Bai S, Sharma SM, Frankel W, Jacob ST.

J Biol Chem. 2004 Feb 20;279(8):6783-93. Epub 2003 Nov 10.


Genome-wide binding of MBD2 reveals strong preference for highly methylated loci.

Menafra R, Brinkman AB, Matarese F, Franci G, Bartels SJ, Nguyen L, Shimbo T, Wade PA, Hubner NC, Stunnenberg HG.

PLoS One. 2014 Jun 13;9(6):e99603. doi: 10.1371/journal.pone.0099603. eCollection 2014.


Preferential binding of the methyl-CpG binding domain protein 2 at methylated transcriptional start site regions.

Chatagnon A, Perriaud L, Nazaret N, Croze S, Benhattar J, Lachuer J, Dante R.

Epigenetics. 2011 Nov;6(11):1295-307. doi: 10.4161/epi.6.11.17875. Epub 2011 Nov 1.


Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer.

Stirzaker C, Song JZ, Ng W, Du Q, Armstrong NJ, Locke WJ, Statham AL, French H, Pidsley R, Valdes-Mora F, Zotenko E, Clark SJ.

Oncogene. 2017 Mar;36(10):1328-1338. doi: 10.1038/onc.2016.297. Epub 2016 Sep 5.


Reduced mRNA expression levels of MBD2 and MBD3 in gastric carcinogenesis.

Pontes TB, Chen ES, Gigek CO, Calcagno DQ, Wisnieski F, Leal MF, Demachki S, Assumpção PP, Artigiani R, Lourenço LG, Burbano RR, Arruda Cardoso Smith M.

Tumour Biol. 2014 Apr;35(4):3447-53. doi: 10.1007/s13277-013-1455-y. Epub 2013 Dec 13.


Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy.

Cui Y, Irudayaraj J.

Nucleic Acids Res. 2015 Mar 31;43(6):3046-55. doi: 10.1093/nar/gkv098. Epub 2015 Mar 9.


Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.

Zhang Y, Ng HH, Erdjument-Bromage H, Tempst P, Bird A, Reinberg D.

Genes Dev. 1999 Aug 1;13(15):1924-35.


The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.

Choi WI, Jeon BN, Yoon JH, Koh DI, Kim MH, Yu MY, Lee KM, Kim Y, Kim K, Hur SS, Lee CE, Kim KS, Hur MW.

Nucleic Acids Res. 2013 Jul;41(13):6403-20. doi: 10.1093/nar/gkt359. Epub 2013 May 8.

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