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Items: 1 to 20 of 68

1.

High frequency targeted mutagenesis using engineered endonucleases and DNA-end processing enzymes.

Delacôte F, Perez C, Guyot V, Duhamel M, Rochon C, Ollivier N, Macmaster R, Silva GH, Pâques F, Daboussi F, Duchateau P.

PLoS One. 2013;8(1):e53217. doi: 10.1371/journal.pone.0053217.

2.

Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways.

Qi Y, Zhang Y, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF.

Genome Res. 2013 Mar;23(3):547-54. doi: 10.1101/gr.145557.112.

3.

Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases.

Kawai N, Ochiai H, Sakuma T, Yamada L, Sawada H, Yamamoto T, Sasakura Y.

Dev Growth Differ. 2012 Jun;54(5):535-45. doi: 10.1111/j.1440-169X.2012.01355.x.

PMID:
22640377
4.

Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana.

Fauser F, Schiml S, Puchta H.

Plant J. 2014 Jul;79(2):348-59. doi: 10.1111/tpj.12554.

5.

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.

Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, Scharenberg AM.

Nat Methods. 2012 Oct;9(10):973-5. doi: 10.1038/nmeth.2177.

6.
7.

Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells.

Morton J, Davis MW, Jorgensen EM, Carroll D.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16370-5.

8.

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases.

Redondo P, Prieto J, Muñoz IG, Alibés A, Stricher F, Serrano L, Cabaniols JP, Daboussi F, Arnould S, Perez C, Duchateau P, Pâques F, Blanco FJ, Montoya G.

Nature. 2008 Nov 6;456(7218):107-11. doi: 10.1038/nature07343.

PMID:
18987743
9.

Lipofection and nucleofection of substrate plasmid can generate widely different readings of DNA end-joining efficiency in different cell lines.

Magin S, Saha J, Wang M, Mladenova V, Coym N, Iliakis G.

DNA Repair (Amst). 2013 Feb 1;12(2):148-60. doi: 10.1016/j.dnarep.2012.11.008.

PMID:
23286905
10.
11.

Targeted mutagenesis in Arabidopsis using zinc-finger nucleases.

Zhang F, Voytas DF.

Methods Mol Biol. 2011;701:167-77. doi: 10.1007/978-1-61737-957-4_9.

PMID:
21181530
12.

Biological and biomedical applications of engineered nucleases.

Pan Y, Xiao L, Li AS, Zhang X, Sirois P, Zhang J, Li K.

Mol Biotechnol. 2013 Sep;55(1):54-62. doi: 10.1007/s12033-012-9613-9. Review.

PMID:
23089945
13.

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.

Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK.

Nucleic Acids Res. 2012 Jul;40(12):5560-8. doi: 10.1093/nar/gks179.

15.

A rapid assay to quantify the cleavage efficiency of custom-designed nucleases in planta.

Johnson RA, Gurevich V, Levy AA.

Plant Mol Biol. 2013 Jun;82(3):207-21. doi: 10.1007/s11103-013-0052-1.

PMID:
23625357
16.

Non-homologous end joining is the responsible pathway for the repair of fludarabine-induced DNA double strand breaks in mammalian cells.

de Campos-Nebel M, Larripa I, González-Cid M.

Mutat Res. 2008 Nov 10;646(1-2):8-16. doi: 10.1016/j.mrfmmm.2008.08.013.

PMID:
18812179
17.
18.

Biochemical mechanisms of chromosomal translocations resulting from DNA double-strand breaks.

Povirk LF.

DNA Repair (Amst). 2006 Sep 8;5(9-10):1199-212. Review.

PMID:
16822725
19.

Cyclin-dependent kinase-dependent phosphorylation of Lif1 and Sae2 controls imprecise nonhomologous end joining accompanied by double-strand break resection.

Matsuzaki K, Terasawa M, Iwasaki D, Higashide M, Shinohara M.

Genes Cells. 2012 Jun;17(6):473-93. doi: 10.1111/j.1365-2443.2012.01602.x.

20.

Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres.

Morrish TA, Garcia-Perez JL, Stamato TD, Taccioli GE, Sekiguchi J, Moran JV.

Nature. 2007 Mar 8;446(7132):208-12.

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