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Items: 1 to 20 of 131

1.

Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.

Atkinson SC, Dogovski C, Downton MT, Czabotar PE, Dobson RC, Gerrard JA, Wagner J, Perugini MA.

Plant Mol Biol. 2013 Mar;81(4-5):431-46. doi: 10.1007/s11103-013-0014-7.

PMID:
23354837
2.

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.

Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, Perugini MA, Gerrard JA, Weiss MS, Dobson RC.

Biochem J. 2008 Apr 15;411(2):351-60.

PMID:
18062777
3.

Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine.

Atkinson SC, Dogovski C, Downton MT, Pearce FG, Reboul CF, Buckle AM, Gerrard JA, Dobson RC, Wagner J, Perugini MA.

PLoS One. 2012;7(6):e38318. doi: 10.1371/journal.pone.0038318.

4.

Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine.

Conly CJ, Skovpen YV, Li S, Palmer DR, Sanders DA.

Biochemistry. 2014 Dec 2;53(47):7396-406. doi: 10.1021/bi5012157.

PMID:
25369463
5.
6.

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera.

Atkinson SC, Dogovski C, Newman J, Dobson RC, Perugini MA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1537-41. doi: 10.1107/S1744309111038395.

7.

Characterization of a thermostable dihydrodipicolinate synthase from Thermoanaerobacter tengcongensis.

Wolterink-van Loo S, Levisson M, Cabrières MC, Franssen MC, van der Oost J.

Extremophiles. 2008 May;12(3):461-9. doi: 10.1007/s00792-008-0152-z.

PMID:
18340401
8.

Feedback inhibition of dihydrodipicolinate synthase enzymes by L-lysine.

Blickling S, Knäblein J.

Biol Chem. 1997 Mar-Apr;378(3-4):207-10. Review.

PMID:
9165072
9.

How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?

Soares da Costa TP, Muscroft-Taylor AC, Dobson RC, Devenish SR, Jameson GB, Gerrard JA.

Biochimie. 2010 Jul;92(7):837-45. doi: 10.1016/j.biochi.2010.03.004.

PMID:
20353808
10.
11.

New insights into the mechanism of dihydrodipicolinate synthase using isothermal titration calorimetry.

Muscroft-Taylor AC, Soares da Costa TP, Gerrard JA.

Biochimie. 2010 Mar;92(3):254-62. doi: 10.1016/j.biochi.2009.12.004.

PMID:
20025926
13.

Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production.

Geng F, Chen Z, Zheng P, Sun J, Zeng AP.

Appl Microbiol Biotechnol. 2013 Mar;97(5):1963-71. doi: 10.1007/s00253-012-4062-8.

PMID:
22644522
14.
15.

Structural and dynamic requirements for optimal activity of the essential bacterial enzyme dihydrodipicolinate synthase.

Reboul CF, Porebski BT, Griffin MD, Dobson RC, Perugini MA, Gerrard JA, Buckle AM.

PLoS Comput Biol. 2012;8(6):e1002537. doi: 10.1371/journal.pcbi.1002537.

17.

Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase.

Girish TS, Sharma E, Gopal B.

FEBS Lett. 2008 Aug 20;582(19):2923-30. doi: 10.1016/j.febslet.2008.07.035.

18.

Structure of dihydrodipicolinate synthase of Nicotiana sylvestris reveals novel quaternary structure.

Blickling S, Beisel HG, Bozic D, Knäblein J, Laber B, Huber R.

J Mol Biol. 1997 Dec 12;274(4):608-21.

PMID:
9417939
19.

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.

Domigan LJ, Scally SW, Fogg MJ, Hutton CA, Perugini MA, Dobson RC, Muscroft-Taylor AC, Gerrard JA, Devenish SR.

Biochim Biophys Acta. 2009 Oct;1794(10):1510-6. doi: 10.1016/j.bbapap.2009.06.020.

PMID:
19595801
20.

Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana.

Griffin MD, Billakanti JM, Wason A, Keller S, Mertens HD, Atkinson SC, Dobson RC, Perugini MA, Gerrard JA, Pearce FG.

PLoS One. 2012;7(7):e40318. doi: 10.1371/journal.pone.0040318.

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